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Annals of the New York Academy of Sciences, 1990
The poxvirus family, subfamily Chordopoxviridae, contains six genera. The basic criteria distinguishing membership in a genus is cross-neutralization and host-range predilection. Members of the genus Orthopoxvirus (vaccinia) and of the genus Avipoxvirus (fowlpox) have been genetically engineered to express genes from heterologous pathogens, thus ...
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The poxvirus family, subfamily Chordopoxviridae, contains six genera. The basic criteria distinguishing membership in a genus is cross-neutralization and host-range predilection. Members of the genus Orthopoxvirus (vaccinia) and of the genus Avipoxvirus (fowlpox) have been genetically engineered to express genes from heterologous pathogens, thus ...
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The Evolution of Poxvirus Vaccines [PDF]
Viruses, 2015 After Edward Jenner established human vaccination over 200 years ago, attenuated poxviruses became key players to contain the deadliest virus of its own family: Variola virus (VARV), the causative agent of smallpox. Cowpox virus (CPXV) and horsepox virus (HSPV) were extensively used to this end, passaged in cattle and humans until the appearance of ...
Beatriz Perdiguero +2 more
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2004
Biochemical and functional analysis of poxvirus genomes, genes, and proteins has entered a new era with the recent sequencing of more than 30 poxvirus genomes. The management and analysis of this volume of sequence data in an efficient and effective manner requires specialized computer software.
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Biochemical and functional analysis of poxvirus genomes, genes, and proteins has entered a new era with the recent sequencing of more than 30 poxvirus genomes. The management and analysis of this volume of sequence data in an efficient and effective manner requires specialized computer software.
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1969
Only a short time has elapsed since the poxvirus literature was reviewed in a most thorough and comprehensive fashion (Joklik, 1966). It is the purpose of this communication to focus in somewhat more detail on a single facet of the overall picture, the poxvirus-coded proteins or antigens.
W C, Wilcox, G H, Cohen
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Only a short time has elapsed since the poxvirus literature was reviewed in a most thorough and comprehensive fashion (Joklik, 1966). It is the purpose of this communication to focus in somewhat more detail on a single facet of the overall picture, the poxvirus-coded proteins or antigens.
W C, Wilcox, G H, Cohen
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Current Opinion in Virology, 2012
Poxviruses are characterized by their large size, complex composition, and cytoplasmic life cycle. They produce two types of infectious particles: mature virions (MVs) and extracellular virions (EVs). Both MVs and EVs of vaccinia virus, the model poxvirus, take advantage of host cell endocytosis for internalization: they activate macropinocytosis-the ...
Schmidt Florian I. +2 more
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Poxviruses are characterized by their large size, complex composition, and cytoplasmic life cycle. They produce two types of infectious particles: mature virions (MVs) and extracellular virions (EVs). Both MVs and EVs of vaccinia virus, the model poxvirus, take advantage of host cell endocytosis for internalization: they activate macropinocytosis-the ...
Schmidt Florian I. +2 more
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POXVIRUS INFECTION AND APOPTOSIS
International Reviews of Immunology, 2004The following excellent reviews have been published on poxviruses and apoptosis during the last few years: P.C. Turner and R.W. Moyer, Semin. Virology, 8: 453-469, 1998; J.L. Shisler and B. Moss, Semin. Immunol., 13: 67-72, 2001; and H. Everett and G. McFadden, Curr. Opin. Microbiol., 5: 395-402, 2002.
Beatriz G-T, Pogo +2 more
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1992
The poxviruses form a large family of complex DNA viruses that infect both vertebrate and invertebrate hosts. The most notorious member, variola virus, was responsible for smallpox, one of the most dreaded of all infectious diseases. In the late 18th century, Edward Jenner demonstrated that smallpox could be prevented by immunization with a more benign
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The poxviruses form a large family of complex DNA viruses that infect both vertebrate and invertebrate hosts. The most notorious member, variola virus, was responsible for smallpox, one of the most dreaded of all infectious diseases. In the late 18th century, Edward Jenner demonstrated that smallpox could be prevented by immunization with a more benign
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Illnesses caused by poxviruses have plagued humanity for millennia. The most notable are caused by viruses comprising the orthopoxvirus genus. Smallpox (caused by Variola virus) became the first eradicated disease in 1980. Devotion to smallpox eradication required significant orthopoxvirus research and discovery including vaccine and medical ...
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