Results 41 to 50 of about 2,366 (165)

Atomic structure of the human cytomegalovirus capsid with its securing tegument layer of pp150 [PDF]

open access: yesScience, 2017
Strong under pressure Human cytomegalovirus (HCMV) is a member of the herpesvirus family that can cause life-threatening infections in those who are immunocompromised. HCMV encodes a genome that is about 50% larger than that of herpes simplex virus 1 (the virus that causes cold sores), but these two viruses have ...
Xuekui Yu   +3 more
openaire   +4 more sources

Highly quantitative serological detection of anti-cytomegalovirus (CMV) antibodies

open access: yesVirology Journal, 2009
Background Human cytomegalovirus infection is associated with a variety of pathological conditions including retinitis, pneumonia, hepatitis and encephalitis that may be transmitted congenitally, horizontally and parenterally and occurs both as a primary
Alter Harvey J   +6 more
doaj   +1 more source

Prokaryotic Expression of Immunogenic Polypeptides of the Large Phosphoprotein (pp150) of Human Cytomegalovirus

open access: yesJournal of General Virology, 1988
The large phosphorylated matrix protein pp150 of human cytomegalovirus (HCMV) is the polypeptide most frequently reactive in immunoblotting analyses with human antisera when compared with other viral proteins. Several defined regions of pp150 were expressed as beta-galactosidase fusion proteins and these were tested for their immunoreactivity with ...
B C, Scholl   +5 more
openaire   +2 more sources

Establishment of an indirect ELISA method for detection of human cytomegalovirus [PDF]

open access: yes精准医学杂志
Objective To establish an indirect ELISA method for the detection of human cytomegalovirus (HCMV) based on HCMV IE1/pp65/pp150 recombinant protein. Methods From June to December 2024, 5 serum samples from HCMV IgG-positive patients, 50 serum samples from
LI Xu, WANG Shan, HUANG Huan, WANG Bin, QIAN Dongmeng
doaj   +1 more source

NKG2C+CD57+ Natural Killer Cell Expansion Parallels Cytomegalovirus‐Specific CD8+ T Cell Evolution towards Senescence

open access: yesJournal of Immunology Research, Volume 2016, Issue 1, 2016., 2016
Objective. Measuring NKG2C+CD57+ natural killer (NK) cell expansion to investigate NK responses against human cytomegalovirus (HCMV) and assessing relationships with adaptive immunity against HCMV. Methods. Expansion of NKG2C+CD57+ NK was measured in peripheral blood mononuclear cells (PBMC) from groups distinguished by HCMV and human immunodeficiency ...
John Heath   +6 more
wiley   +1 more source

Hybrid P2P Architecture for Transaction Management [PDF]

open access: yes, 2013
In contrast with many centralised schemes P2P systems are flexible, scalable and highly dynamic. They offer an attractive distributed platform despite concerns over security.
Anane, Rachid, Marrocco, S.
core   +1 more source

Human Cytomegalovirus and Autoimmune Disease

open access: yesBioMed Research International, Volume 2014, Issue 1, 2014., 2014
Human cytomegalovirus (HCMV) represents a prototypic pathogenic member of the β‐subgroup of the herpesvirus family. A range of HCMV features like its lytic replication in multiple tissues, the lifelong persistence through periods of latency and intermitting reactivation, the extraordinary large proteome, and extensive manipulation of adaptive and ...
Anne Halenius   +2 more
wiley   +1 more source

Multiplex immunoassay for detection of immunoglobulin G to herpes simplex virus types 1, 2 and cytomegalovirus based on PHOSPHAN technology

open access: yesВопросы вирусологии, 2017
We have developed a multiplex immunoassay test (immunochip) based on PHOSPHAN technology for the detection of immunoglobulin G to herpes simplex virus (HSV) types 1, 2 and cytomegalovirus (CMV).
A. V. Nikitina   +3 more
doaj   +1 more source

Human cytomegalovirus exploits interferon-induced transmembrane proteins to facilitate morphogenesis of the virion assembly compartment [PDF]

open access: yes, 2014
Recently, interferon-induced transmembrane proteins (IFITMs) have been identified to be key effector molecules in the host type I interferon defense system.
Li, Bin   +9 more
core   +2 more sources

RNA-binding protein CPEB1 remodels host and viral RNA landscapes. [PDF]

open access: yes, 2016
Host and virus interactions occurring at the post-transcriptional level are critical for infection but remain poorly understood. Here, we performed comprehensive transcriptome-wide analyses revealing that human cytomegalovirus (HCMV) infection results in
Aigner, Stefan   +17 more
core   +2 more sources

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