Results 91 to 100 of about 14,919 (212)

Exploring neuroprotective effects of PP2 in ischemic stroke via bioinformatics and experimental validation

Neurological Research
Ischemic stroke is a leading cause of mortality and disability worldwide, yet effective therapeutic options remain limited. In this study, bioinformatics analyses were used to identify potential therapeutic targets and small-molecule compounds for ischemic stroke.
Shiyan Zhao, Jun Lu, Yanyan Zhao, Chang Qi, Chunrong Han   +4 more
openaire   +2 more sources

Src family kinase inhibitor PP2 accelerates differentiation in human intestinal epithelial cells

Biochemical and Biophysical Research Communications, 2013
The proto-oncogene Src is an important protein tyrosine kinase involved in signaling pathways that control cell adhesion, growth, migration and survival. Here, we investigated the involvement of Src family kinases (SFKs) in human intestinal cell differentiation.
Seltana, Amira, Guezguez, Amel, Lepage, Manon, Basora, Nuria, Beaulieu, Jean-François   +4 more
openaire   +2 more sources

IP-FCM detects the specific inhibition of antigen-inducible ZAP70 recruitment by the small molecule src-family kinase inhibitor, PP2.

, 2013
OT1 TCR transgenic T cells were pre-incubated with 10 µM of either PP2, a known src-kinase inhibitor, or one of several other small-molecule control compounds.
Steven E. Patterson (306340), Diana Gil (306341), Anya T. Bida (306335), Hugues Sicotte (14304), Tessa R. Davis (306338), Adam G. Schrum (306342), Stephen E. P. Smith (306332)   +6 more
core   +1 more source

CY1 VIGS vector targeting mRNA of 2 PP2 family members decreases CY1 accumulation in systemic leaves.

(A) Hairpin used to target the 2 PP2 mRNAs and similarly sized random hairpin. Hairpins replaced the natural hairpin at position 2220. Agrobacteria constructs harboring either PEMV2, CY1 WT, CY1-PP2, or CY1-random were agroinfiltrated into N. benthamiana
Xiaobao Ying (18446889), Sayanta Bera (18446892), Jinyuan Liu (132153), Jovia Ho (18446898), Roberto Toscano-Morales (678967), Stephen Yang (8780722), Chanyong Jang (18446895), Anne E. Simon (5988461)   +7 more
core   +1 more source

PP2 promotes expression of genes involved in glycosaminoglycan synthesis

, 2011
Copyright information:Taken from "Src kinase inhibition promotes the chondrocyte phenotype"http://arthritis-research.com/content/9/5/R105Arthritis Research & Therapy 2007;9(5):R105-R105.Published online 10 Oct 2007PMCID:PMC2212572.
Claudine G James (39174), Anita Woods (39173), Andrew Leask (18879), Frank Beier (28381), Laura Bursell (39172), Daphne Pala (39175)   +5 more
core   +1 more source

CD38 and CD11b expression, cell cycle progression, and p47^phox expression in control, PP2- and/or RA-treated R38+ and R38− HL60 cells.

, 2013
Error bars represent standard error of at least three repeats. P values were calculated using a student’s t test and are compared between untreated respective control unless otherwise indicated.
Johanna Congleton (390457), Lauren E. Styskal (390455), Rodica P. Bunaciu (390456), Ryan Tasseff (253998), Andrew Yen (390458), Holly A. Jensen (390454), Jeffrey D. Varner (197251)   +6 more
core   +1 more source

Adubação do milho com superfosfato triplo em Latossolo Vermelho sob efeito residual de fontes alternativas de fósforo

Revista de Ciências Agroveterinárias, 2018
O uso de fontes alternativas na adubação fosfatada em solos de carga variável pode influenciar a adubação com fosfato solúvel. O objetivo do trabalho foi avaliar a eficiência na disponibilidade de fósforo (P) para a cultura do milho em resposta a ...
Caio Vilela Cruz, Dirceu Maximino fernandes, Marco Andre Grohskopf, Igor Vilela Cruz   +3 more
doaj   +1 more source

(A) Effect of PP2 on PKCδ tyrosine phosphorylation.

, 2013
Human washed platelets were treated with 0.1 or 1 U/ml thrombin for 1 min in the presence or absence of PP2 (10 µM, 5 min). Immunoprecipitations and reprobes were carried out as described in the methods.
Majd B. Protty (375672), Kelly Thornber (375670), Andrew C. Pearce (375673), Jocelyn M. Auger (249578), Beata Grygielska (375671), Steve P. Watson (74991), Craig E. Hughes (108775), Catherine J. Pears (364958)   +7 more
core   +1 more source

Identification and expression characterization of the Phloem Protein 2 (PP2) genes in ramie (Boehmeria nivea L. Gaudich)

Scientific Reports, 2018
Phloem protein 2 (PP2) is one of the most abundant and enigmatic proteins in sieve elements and companion cells, which play important roles in the maintenance of morphology, photoassimilate transportation and wound protection in higher plants, but to ...
Pingan Guo, Yancheng Zheng, Dingxiang Peng, Lijun Liu, Lunjin Dai, Cong Chen, Bo Wang   +6 more
doaj   +1 more source

RBD-induced neurite sprouting is blocked in primary sensory neurons pre-treated with a Src-family kinase inhibitor, PP2.

, 2013
A, Phase-contrast images of cultured sensory neurons after 2 weeks of treatment. Note the reduction of sprouting in RBD (100 nM) treated cultures, but not NGF (50 ng/ml) treated cultures with treatment of PP2 (1 µM) for 30 min prior to the addition of ...
Tomonori Yamauchi (462278), Kenneth Henry (299008), Elisabetta Mantuano (462279), Kazuyo Yamauchi (462277), Kenichi Murakami (462280), Kazuhisa Takahashi (118725), Wendy Marie Campana (462281)   +6 more
core   +1 more source