Results 71 to 80 of about 113,385 (285)

The relationship between form and function of the carnivore mandible

open access: yesThe Anatomical Record, EarlyView.
Abstract Dietary morphology diversified extensively in Carnivoraformes (living Carnivora and their stem relatives) during the Cenozoic (the last 66 million years) as they evolved to capture, handle, and process new animal and plant diets. We used 3D geometric morphometrics, mechanical advantage, and finite element analysis to test the evolutionary ...
Charles J. Salcido, P. David Polly
wiley   +1 more source

Economic Benefit of Aflibercept 8 mg Versus Faricimab for Neovascular Age-Related Macular Degeneration or Diabetic Macular Edema in the US

open access: yesOphthalmology and Therapy
Introduction The aim of this study was to compare the estimated direct and indirect costs with aflibercept 8 mg and faricimab in patients with neovascular age-related macular degeneration (nAMD) or diabetic macular edema (DME) over 5 years.
Andreas Kuznik   +5 more
doaj   +1 more source

Paraphenylenediamine Poisoning in Tunisia: A Case Report

open access: yesArab Journal of Forensic Sciences & Forensic Medicine, 2015
Paraphenylenediamine (PPD) represents the main active substance in the color of hair dyes. In Tunisia, PPD poisoning is very common, especially in rural areas where the consequences linked to this toxic substance are still unknown.
Dorra Amira   +8 more
doaj   +1 more source

Zuranolone: A case study in (regulatory) rush to judgement?

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove   +4 more
wiley   +1 more source

Development of a conceptual model of early systemic sclerosis (scleroderma)

open access: yesOrphanet Journal of Rare Diseases
Background Systemic sclerosis (SSc) is a rare connective tissue disorder with heterogeneous manifestations. Two predominant subtypes, limited cutaneous SSc (lcSSc) and diffuse cutaneous SSc (dcSSc), are distinguished based on skin involvement ...
William R. Lenderking   +7 more
doaj   +1 more source

Effect of chromosome 3B gene/s of Česká Přesívka on vernalisation response, photoperiod sensitivity and earliness of wheat

open access: yesCzech Journal of Genetics and Plant Breeding, 2002
Substitution lines with the chromosome 3B of the Czech alternative cultivar Česká Přesívka (CP) in the genetic background of the wheat cultivars Zdar, Vala, Košutka, Jara and Sandra, differing in their requirements of vernalisation and photoperiod, were ...
J. Košner, K. Pánková
doaj   +1 more source

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

open access: yesBMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma   +9 more
wiley   +1 more source

Evaluation of Tuberculin Skin Test Seroconversion Among the Staff in Qaemshahr Razi Hospital, 2015-2017

open access: yesJournal of Mazandaran University of Medical Sciences, 2018
Background and purpose: Tuberculosis is a contagious disease caused by mycobacterium tuberculosis. Approximately 30% of the world's population is infected, 5-10% of whom develop active tuberculosis.
Lotfollah Davoodi   +3 more
doaj  

Activation of 5-HT 2A Receptor Disrupts Rat Maternal Behavior [PDF]

open access: yes, 2019
Serotonin 5-HT2A receptor is widely distributed in the central nervous system and plays an important role in sensorimotor function, emotion regulation, motivation, executive control, learning and memory. We investigated its role in rat maternal behavior,
Davis, Collin   +3 more
core   +1 more source

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