Results 51 to 60 of about 37,147 (263)

Seasonal variations of peach fruit fly, Bactrocera zonata Saunder under the impact of host fruits and meteorological factors

open access: yesРастениевъдни науки, 2021
Peach fruit fly, Bactrocera zonata is a widely distributed and devastating pest of fruit with global significance. Its population dynamics are greatly influenced by the climatic factors and availability of fruits.
Ahmed Khan   +2 more
doaj  

Zuranolone: A case study in (regulatory) rush to judgement?

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove   +4 more
wiley   +1 more source

Development of a conceptual model of early systemic sclerosis (scleroderma)

open access: yesOrphanet Journal of Rare Diseases
Background Systemic sclerosis (SSc) is a rare connective tissue disorder with heterogeneous manifestations. Two predominant subtypes, limited cutaneous SSc (lcSSc) and diffuse cutaneous SSc (dcSSc), are distinguished based on skin involvement ...
William R. Lenderking   +7 more
doaj   +1 more source

Safety and pharmacokinetics of mosliciguat, a new, inhaled soluble guanylate cyclase activator, in healthy adult subjects

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mosliciguat (BAY 1237592), the first soluble guanylate cyclase (sGC) activator in a dry powder inhaler (DPI), could potentially treat pulmonary hypertension with a more targeted delivery than systemic sGC stimulators. We report safety and tolerability of mosliciguat in healthy men.
Johannes Nagelschmitz   +7 more
wiley   +1 more source

Evaluation of Tuberculin Skin Test Seroconversion Among the Staff in Qaemshahr Razi Hospital, 2015-2017

open access: yesJournal of Mazandaran University of Medical Sciences, 2018
Background and purpose: Tuberculosis is a contagious disease caused by mycobacterium tuberculosis. Approximately 30% of the world's population is infected, 5-10% of whom develop active tuberculosis.
Lotfollah Davoodi   +3 more
doaj  

Economic Benefit of Aflibercept 8 mg Versus Faricimab for Neovascular Age-Related Macular Degeneration or Diabetic Macular Edema in the US

open access: yesOphthalmology and Therapy
Introduction The aim of this study was to compare the estimated direct and indirect costs with aflibercept 8 mg and faricimab in patients with neovascular age-related macular degeneration (nAMD) or diabetic macular edema (DME) over 5 years.
Andreas Kuznik   +5 more
doaj   +1 more source

Paraphenylenediamine Poisoning in Tunisia: A Case Report

open access: yesArab Journal of Forensic Sciences & Forensic Medicine, 2015
Paraphenylenediamine (PPD) represents the main active substance in the color of hair dyes. In Tunisia, PPD poisoning is very common, especially in rural areas where the consequences linked to this toxic substance are still unknown.
Dorra Amira   +8 more
doaj   +1 more source

Development of a nalmefene formulation suitable for a community‐use auto‐injector

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Time to onset of reversal is critical when treating opioid‐induced respiratory depression and hypoxia. This study aimed to develop a formulation of the opioid antagonist nalmefene with an increased absorption rate and reduced time to onset of reversal following intramuscular administration. Methods Several absorption enhancers were screened in rats,
Alessandra Cipriano   +6 more
wiley   +1 more source

Development of the Patient Satisfaction with Medication for Diabetes (PSMD) questionnaire

open access: yesJournal of Patient-Reported Outcomes
Background Recent advances in treatment for type 1 (T1D) and type 2 diabetes (T2D) may have an impact on patients’ treatment satisfaction, which can affect adherence and outcomes.
Kristina S. Boye   +7 more
doaj   +1 more source

Effect of chromosome 3B gene/s of Česká Přesívka on vernalisation response, photoperiod sensitivity and earliness of wheat

open access: yesCzech Journal of Genetics and Plant Breeding, 2002
Substitution lines with the chromosome 3B of the Czech alternative cultivar Česká Přesívka (CP) in the genetic background of the wheat cultivars Zdar, Vala, Košutka, Jara and Sandra, differing in their requirements of vernalisation and photoperiod, were ...
J. Košner, K. Pánková
doaj   +1 more source

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