Results 51 to 60 of about 37,147 (263)
Peach fruit fly, Bactrocera zonata is a widely distributed and devastating pest of fruit with global significance. Its population dynamics are greatly influenced by the climatic factors and availability of fruits.
Ahmed Khan +2 more
doaj
Zuranolone: A case study in (regulatory) rush to judgement?
Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove +4 more
wiley +1 more source
Development of a conceptual model of early systemic sclerosis (scleroderma)
Background Systemic sclerosis (SSc) is a rare connective tissue disorder with heterogeneous manifestations. Two predominant subtypes, limited cutaneous SSc (lcSSc) and diffuse cutaneous SSc (dcSSc), are distinguished based on skin involvement ...
William R. Lenderking +7 more
doaj +1 more source
Abstract Aim Mosliciguat (BAY 1237592), the first soluble guanylate cyclase (sGC) activator in a dry powder inhaler (DPI), could potentially treat pulmonary hypertension with a more targeted delivery than systemic sGC stimulators. We report safety and tolerability of mosliciguat in healthy men.
Johannes Nagelschmitz +7 more
wiley +1 more source
Background and purpose: Tuberculosis is a contagious disease caused by mycobacterium tuberculosis. Approximately 30% of the world's population is infected, 5-10% of whom develop active tuberculosis.
Lotfollah Davoodi +3 more
doaj
Introduction The aim of this study was to compare the estimated direct and indirect costs with aflibercept 8 mg and faricimab in patients with neovascular age-related macular degeneration (nAMD) or diabetic macular edema (DME) over 5 years.
Andreas Kuznik +5 more
doaj +1 more source
Paraphenylenediamine Poisoning in Tunisia: A Case Report
Paraphenylenediamine (PPD) represents the main active substance in the color of hair dyes. In Tunisia, PPD poisoning is very common, especially in rural areas where the consequences linked to this toxic substance are still unknown.
Dorra Amira +8 more
doaj +1 more source
Development of a nalmefene formulation suitable for a community‐use auto‐injector
Aim Time to onset of reversal is critical when treating opioid‐induced respiratory depression and hypoxia. This study aimed to develop a formulation of the opioid antagonist nalmefene with an increased absorption rate and reduced time to onset of reversal following intramuscular administration. Methods Several absorption enhancers were screened in rats,
Alessandra Cipriano +6 more
wiley +1 more source
Development of the Patient Satisfaction with Medication for Diabetes (PSMD) questionnaire
Background Recent advances in treatment for type 1 (T1D) and type 2 diabetes (T2D) may have an impact on patients’ treatment satisfaction, which can affect adherence and outcomes.
Kristina S. Boye +7 more
doaj +1 more source
Substitution lines with the chromosome 3B of the Czech alternative cultivar Česká Přesívka (CP) in the genetic background of the wheat cultivars Zdar, Vala, Košutka, Jara and Sandra, differing in their requirements of vernalisation and photoperiod, were ...
J. Košner, K. Pánková
doaj +1 more source

