Results 31 to 40 of about 37,147 (263)

“My dream is to not have to be on a diet”: a qualitative study on burdens of classical homocystinuria (HCU) from the patient perspective

Orphanet Journal of Rare Diseases
Background Patients with classical homocystinuria (HCU) are unable to metabolize homocysteine and rely on dietary treatment to reduce their risk of complications (e.g., thromboembolism, cognitive impairment).
Robin Pokrzywinski, Danaé Bartke, Claudine Clucas, Kathy Machuzak, Lionel Pinto   +4 more
doaj   +1 more source

Synergistic Ni Single Atoms/Nanoparticles on CeO2 for High‐Performance and Durable SOFC Hydrogen Electrodes

Advanced Science, EarlyView.
Combination of UiO‐66(Ce) metal organic framework‐templated synthesis and in‐situ exsolution creates porous CeO2‐based anode decorated with Ni single atoms/nanoparticles, synergy of which leads to enhanced electronic/ionic transport, accelerated H2 oxidation, improved stability, and finally outstanding peak power density among oxide‐based SOFC anodes ...
Mengting Liu, Fengyang Yu, Qian Yang, Li Li, Yuesong Shen, Ling Huang   +5 more
wiley   +1 more source

Patient Preferences for Self-Injectable Preventive Treatment for Migraine: A Multi-country Discrete Choice Experiment

Neurology and Therapy
Introduction Self-injectable calcitonin gene-related peptide monoclonal antibodies (CGRP mAbs) and oral CGRP antagonists are currently available for migraine prevention.
Jaein Seo, Caitlin Thomas, Tommi Tervonen, Nicolas Krucien, Janet H. Ford, Virginia L. Stauffer, Robert A. Nicholson, Kevin Harrison Duffy, Antje Tockhorn-Heidenreich   +8 more
doaj   +1 more source

Thermophysiological Comfort of Surgeons and Patient in an Operating Room Based on PMV-PPD and PHS Indexes

Applied Sciences, 2020
There are different actors in an operating room (OR), who have controversial requirements for the indoor thermal environment. While the patient is at risk of perioperative hypothermia, the surgeons are in a state of thermophysiological discomfort.
Radostina A. Angelova, Rositsa Velichkova   +1 more
doaj   +1 more source

Polarization Engineering in Vinylene‐Linked COFs Toward Efficient Neuromorphic Computing

Advanced Science, EarlyView.
A vinyl‐linked covalent organic framework (COF‐DIBPY) was synthesized on a conductive substrate for memristor applications. Redox reactions and bromide migration enable low‐voltage (0.5V) conductance switching with high analog on/off ratio (15.7). The device was further integrated into a speech emotion recognition system for acoustic simulation and ...
Hao Wang, Lei Zhao, Haoyuan Yao, Qiongshan Zhang, Fuzhen Xuan, Bin Zhang   +5 more
wiley   +1 more source

Cost-effectiveness of Nivolumab + Platinum Doublet Chemotherapy as Neoadjuvant Treatment for Resectable Non-Small Cell Lung Cancer in England

Oncology and Therapy
Introduction This study aimed to assess the cost-effectiveness of neoadjuvant nivolumab + platinum doublet chemotherapy (PDC) versus relevant comparators in the treatment of patients with non-metastatic (stage IB–IIIA), resectable, non-small cell lung ...
Joel Russell, Mack Harris, Ariel Sun, Benjamin White, Thor-Henrik Brodtkorb, James Brockbank, Stefano Lucherini, Lien Vo, Sandra Milev   +8 more
doaj   +1 more source

Multiplex LC-MS/MS Assays for Clinical Bioanalysis of MEDI4276, an Antibody-Drug Conjugate of Tubulysin Analogue Attached via Cleavable Linker to a Biparatopic Humanized Antibody against HER-2

Antibodies, 2019
Bioanalysis of complex biotherapeutics, such as antibody-drug conjugates (ADCs), is challenging and requires multiple assays to describe their pharmacokinetic (PK) profiles.
Morse Faria, Marlking Peay, Brandon Lam, Eric Ma, Moucun Yuan, Michael Waldron, William R. Mylott, Meina Liang, Anton I. Rosenbaum   +8 more
doaj   +1 more source

Architecture‐Engineered Semi‐Crystalline Microporous Polymer Membranes for Precise Molecular Separation

Advanced Science, EarlyView.
Guided by a Random Forest model, a π–π‐driven ordered stacking strategy deploys functionally distinct substructures to restrict chain segment motion and increase free volume, while preserving the intermolecular interactions that maintain structural integrity.
Zi‐Meng Xu, Hao Zhuo, Song‐Hui Zhi, Xiao‐Feng Zhong, Pan‐Pan Zhang, Si‐Yuan Yang, Wen‐Yong Yang, Guang‐Yong Shen, Ya‐Zhao Li, Yi Li, Ming Xue   +10 more
wiley   +1 more source

A qualitative exploration of the patient disease and treatment burden of end stage renal failure, Post-Renal transplantation and antibody mediated rejection (AMR)

BMC Nephrology
Background End stage renal disease (ESRD) is the irreversible decline in an individual’s kidney function. In severe cases it can be fatal if dialysis or transplantation is not sought.
Nicola Barnes, Joshua Maher, Jane R. Wells, Amy Clark, Nashmel Sargalo, Paul Cordero   +5 more
doaj   +1 more source

Battery‐Inspired Electrochemical Synapses for Neuromorphic Applications

Advanced Science, EarlyView.
Battery‐ion‐inspired synaptic devices integrate diverse electrolyte systems (solid, ion‐gel, liquid) with transition metal oxides, two‐dimensional materials, and organic channels to regulate ion‐electron coupling. By tailoring ion transport and host interactions, these platforms enable controllable plasticity and energy‐efficient implementations for ...
Won Woo Lee, SeongCheol Jang, Wangmyung Choi, Jaewon Park, Jaehyun Hur, Hocheon Yoo, Hyun‐Suk Kim   +6 more
wiley   +1 more source