Results 121 to 130 of about 280,167 (308)

An Experimental Investigation on the Effects of Forming Temperature and Sintering Schedule to the Final Characteristics of Fe92Cu7.5Al0.5 Powder Compacts [PDF]

open access: yes, 2016
This paper presents the development of FeCuAl powder compacts through warm compaction process. A lab-scale uni-axial die compaction rig was designed and fabricated which enabled the powder forming at elevated temperature.
Rahman, Md Mujibur; Universiti Tenaga Nasional, Putrajaya Campus   +2 more
core  

Modulating Calcium Homeostasis via a Biomimetic Scaffold to Rescue Diabetic Ischemic Wounds

open access: yesAdvanced Science, EarlyView.
This strategy addresses impaired microcirculation and loss of extracellular matrix (ECM) guidance in diabetic wound healing. Musc@CP, a nanofibrous dressing combining an ECM‐mimetic chitosan‐pullulan scaffold with muscone, enhances perfusion by attenuating intracellular Ca2+ overload‐associated endothelial dysfunction.
Xiang Zheng   +14 more
wiley   +1 more source

Failure of Bottom-Up Implementation: A Case Study the Improving Welfare Program in West Java [PDF]

open access: yes, 2015
Policy implementation is one of the stages in public policy process. This process often faces diverse issues and challenges. This paper aims to analyse models of policy implementation in a governance system in Indonesia.
Khalid, Kartini Aboo Talib; Institute of Ethnic Studies Universiti Kebangsaan Malaysia, Selangor   +1 more
core  

Miro1 Protects Against Acute Kidney Injury Through Modulating Mitochondrial Homeostasis via Interaction With Sirt6

open access: yesAdvanced Science, EarlyView.
Ischemia‐reperfusion reduces Sirt6 activity, thereby increasing Miro1 acetylation. Hyperacetylated Miro1 exhibits perinuclear distribution and degradation, thereby inducing mitochondrial dysfunction and promoting apoptosis in renal tubular epithelial cells. This pathway reveals a mechanistic link between Sirt6‐mediated deacetylation and Miro1 stability
Lin Wu   +12 more
wiley   +1 more source

Ahcy Acts as an Effector of Hnf4a‐Driven Super‐Enhancer Activation to Alleviate MASLD During Intermittent Fasting

open access: yesAdvanced Science, EarlyView.
Our study identifies an Hnf4a‐driven super‐enhancer of hepatic Ahcy that mediates the protective effects of intermittent fasting against MASLD. Disruption of the Ahcy super‐enhancer reduces Ahcy expression and exacerbates lipid accumulation. This pathway prevents aberrant promoter hypermethylation by maintaining the SAM/SAH balance, as exemplified by ...
Huafeng Chen   +6 more
wiley   +1 more source

PPI Network

open access: yes
Protein-protein interaction (PPI) is a highly specific physical contact established between two or more protein molecules, which results from biochemical events generated by the interaction. These interactions include electrostatic forces, hydrogen bonding and hydrophobic effect.
openaire   +2 more sources

The Analysis of Health System in Malaysia and Indonesia [PDF]

open access: yes, 2015
Health service is the one of an important yardstick will be the progress and stability of a country. This is a descriptive, qualitative study using the social-legal approach.
Arsih, Budi; Universitas Darul Ulum Islamic Centre Sudirman Guppi, Semarang
core  

Crosstalk Between CTSB+ Glioblastoma Cells and S100A10+ Macrophages: A Self‐Reinforcing Circuit Promotes Immune Evasion and Limits Response to Immunotherapy

open access: yesAdvanced Science, EarlyView.
In glioblastoma, M2‐polarized macrophages secrete IL‐6, which activates STAT3 signaling in tumor cells to upregulate CTSB. Tumor‐derived CTSB binds the C‐terminus of macrophage S100A10, reinforcing M2 polarization and further IL‐6 secretion, thereby establishing a feedforward IL‐6/STAT3/CTSB/S100A10 loop. This cascade drives tumor growth, invasion, and
Hao Zhang   +11 more
wiley   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

open access: yesAdvanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni   +17 more
wiley   +1 more source

: Analisis Distribusi Ikan di Tiga Pelabuhan Perikanan Kabupaten Indramayu (Studi Kasus: PPI Tegal Agung, PPI Karangsong dan PPI Eretan Kulon)

open access: yes, 2012
Kabupaten Indramayu memiliki 14 Pangkalan Pendaratan Ikan (PPI) yang strategis yaitu: PPI Tegalagung, Dadap, Juntinyuat, Lombang, Limbangan, Majakerta, Brondong, Singaraja, Karangsong, Cangkring, Eretan Wetan, Eretan Kulon, Sukahaji dan Ujung Gebang ...
Tanjung, Akbar
core   +1 more source

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