Results 131 to 140 of about 280,167 (308)
An α‐helical peptide, TAB12, designed to mimic the TRIM28 binding interface, competitively disrupts the TRIM28‐BRD7 interaction, thereby blocking ubiquitin‐mediated degradation of the tumor suppressor BRD7. This stabilization unleashes potent anti‐tumor effects across multiple tumor types with a favorable safety profile, offering a feasible strategy ...
Qingqing Wei +10 more
wiley +1 more source
Perspective of Teacher in Dumai-Riau Indonesia Suitability National Examination as A Picture Quality Student [PDF]
The national test is one method that is chosen by the Indonesian government to determine the stage and picture quality of education in Indonesia. However, in reality the national exam is also used as a measure for the condition continue to the next level
Rozamuri, Arif Murti; Universiti Kebangsaan Malaysia Bangi, Selangor. +1 more
core
TIPE1m NPs nanoparticles restore TIPE1 expression, promote RAB7A ubiquitination and degradation, suppress autophagic flux, and resensitize paclitaxel‐resistant triple‐negative breast cancer to therapy. ABSTRACT Acquired paclitaxel (PTX) resistance remains a major obstacle in triple‐negative breast cancer (TNBC) treatment.
Wei Hu +9 more
wiley +1 more source
Treatment Options in Eosinophilic Oesophagitis
Eosinophilic oesophagitis (EoE) is an increasingly prevalent chronic inflammatory disorder diagnosed by the presence of oesophageal symptoms and eosinophilic inflammation on endoscopic histology.
Anna M. Lipowska +2 more
doaj
Integration of DC Households System Generated by Single-Phase Rooftop PVs into Unbalanced Three-Phase Residential Feeder [PDF]
This paper mitigates the integration of DC households that generated by single-phase photovoltaic (PV) into the unbalanced three-phase residential feeder.
Yusman, Yusman; Department of Electrical Engineering, Politeknik Negeri Lhokseumawe +4 more
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CuPB@HA is a CD44‐associated, plaque‐targeted nanozyme that alleviates oxidative stress, inflammation, and lipid accumulation in macrophages. By reducing CD36‐dependent lipid uptake and promoting ABCA1/ABCG1‐mediated cholesterol handling, it improves macrophage function, preferentially accumulates in atherosclerotic lesions, reduces plaque burden, and ...
Jianliang Ou +14 more
wiley +1 more source
The Study of Economic and Social Karst Region East Kutai Regency [PDF]
Karst Mountains is a landscape of limestone mountains are concatenated to form a corridor-biodiversity, ecosystem where the lives of millions of species of flora and fauna supporting life balance.
Irwan, Irwan; Faculty of Forestry, Mulawarman University, Samarinda 75516 East Kalimantan +1 more
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PTEN knockdown activates AKT phosphorylation, promoting Nrf2 nuclear translocation and STAT3 activation, which upregulates GPX4 and antioxidant enzymes HO‐1, SOD1, SOD2, and NQO1. These coordinated changes reduce lipid peroxidation and ROS, inhibit ferroptosis, and ultimately ameliorate cognitive impairment in APP/PS1 transgenic mice, highlighting a ...
Da‐Wei Wang +5 more
wiley +1 more source
Code to run simulations from the publication 'A computational framework for the investigation of phosphoinositide regulation'.
openaire +1 more source
Bayesian Model Averaging. An Application to Forecast Inflation in Colombia [PDF]
An application of Bayesian Model Averaging, BMA, is implemented to construct combined forecasts for the colombian inflation for the short and medium run. A model selection algorithm is applied over a set of linear models with a large dataset of potencial
Eliana González
core

