Results 161 to 170 of about 148,011 (215)

SNOOPPI: a sequence-normalized database of on- and off-target protein-protein interactions. [PDF]

Bioinformatics
Vincoff S, Chatterjee P.
europepmc   +1 more source

Construction Trade Work Is Associated With Accelerated Decline in Kidney Function

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Background Construction workers are exposed to airborne particulates, organic solvents, and metals—agents linked to elevated risk of chronic kidney disease (CKD). Few studies have evaluated whether construction trade work is associated with longitudinal changes in estimated glomerular filtration rate (eGFR), a key indicator of kidney function.
Sammy Almashat, John M. Dement, Marianne Cloeren, Knut Ringen, Miles Fisher, Richard Rinehart   +5 more
wiley   +1 more source

An IscS Persulfide Donates the Sulfur for Ribosomal Protein uL16 Thioamidation

Angewandte Chemie, EarlyView.
YcaO‐catalyzed thioamidation of the ribosomal subunit protein uL16 is widespread in Pseudomonadota bacteria. We identify the iron–sulfur cluster cysteine desulfurase IscS as the sulfur donor via an IscS persulfide and observe direct IscS–uL16 interactions.
Yanqing Xue, Markus W. Voehler, Douglas A. Mitchell   +2 more
wiley   +2 more sources

Baihe Zhimu Decoction ameliorates anxious depression via PI3K/AKT/mTOR pathway‐mediated neuroprotection and inhibition of hippocampal neuronal apoptosis

Animal Models and Experimental Medicine, EarlyView.
Baihe Zhimu Decoction alleviates anxious depression‐like behaviors and protects hippocampal neurons. Chemical profiling and network pharmacology reveal multiple active components acting via the PI3K/AKT/mTOR pathway, enhancing neuronal survival and function, as confirmed by multi‐level in vitro and in vivo validation.
Yuanshan Han, Kexin He, Haolan Yang, Jiacheng Dai, Ronglin Chen, Yang Liu, Yuhong Wang, Lin Tang, Hongqing Zhao   +8 more
wiley   +1 more source

Polyproline: A Synthetic Polypeptide With Unique Properties

Angewandte Chemie, EarlyView.
Poly‐L‐proline is a unique polypeptide distinguished by its well‐defined secondary structures and unusual thermal behavior. This mini review highlights recent advances in the synthesis of poly‐L‐proline by N‐carboxyanhydride (NCA) polymerization, the formation of structurally defined architectures and nanostructures, and emerging strategies that ...
Rosanna Le Scouarnec, Josué M. Galindo, Colin Bonduelle, Andreas Heise   +3 more
wiley   +2 more sources

Proton pump inhibitor use and long-term outcomes in SSc: a real-life analysis from the EUSTAR database. [PDF]

Rheumatology (Oxford)
Bonomi F, Bandini G, Campochiaro C, De Silvestri V, Agachi S, Bergmann C, Distler O, Granel B, Henes J, Iannone F, Idolazzi L, Kerzberg E, Naffaa ME, Poormoghim H, Radic M, Truchetet ME, Bellando Randone S, Matucci Cerinic M, McMahan ZH, Hughes M, EUSTAR Group .   +20 more
europepmc   +1 more source

Impact of an IV proton pump inhibitor restriction policy on prescribing patterns and estimated drug cost. [PDF]

Front Pharmacol
Ibrahim ARN, Alqahtani SA, Alghamdi WA.
europepmc   +1 more source

Physiological, Transcriptional, and Metabolic Responses Associated with Pyrophosphate-Mediated Alleviation of Cadmium Stress in Arabidopsis. [PDF]

Plants (Basel)
Yang Y, Wang L, He P, Wang J, Wang C, Wang C, Jiao Z.   +6 more
europepmc   +1 more source