Results 71 to 80 of about 280,167 (308)

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

Advanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang, Qiang Chen, Aihua Jin, Xiaoqi Yang, Hui Zhou, Weiquan Gong, Jin Cheng, Jun Dai, Minjin Wang, Meihua Piao, Yuanyi Wang, Nan Zhou   +11 more
wiley   +1 more source

Preference Testing in Medical Devices: Current Framework and Regulatory Gaps

Medical Devices: Evidence and Research, 2022
Amy Lewis,1 Despoina Douka,1 Angeliki Koukoura,1 Vasiliki Valla,1 Amie Smirthwaite,2 Susanne Holm Faarbaek,3 Efstathios Vassiliadis1 1Evnia, Copenhagen, Denmark; 2RQM+, Nottingham, England; 3BK Medical, Herlev, DenmarkCorrespondence: Amy Lewis, Email ...
Lewis A, Douka D, Koukoura A, Valla V, Smirthwaite A, Faarbaek SH, Vassiliadis E   +6 more
doaj  

Microglial Deubiquitinase OTUD7B Stabilizes STAT3 to Promote Neuroinflammation and Cognitive Decline in Alzheimer's Disease

Advanced Science, EarlyView.
. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li, Hao Tang, Qin Yu, Yuyang Zhang, Binglu Shi, Ying Kong, Leiyu Xu, Jingjing Shao, Chenghong Hu, Lingyu She, Zhe Wang, Haiyi Chen, Aleksandr V. Samorodov, Gang Cao, Xia Zhao, Yi Wang   +15 more
wiley   +1 more source

Celastrol‐Loaded Conductive Hydrogel Mitigates Myocardial Ischemia‐Reperfusion Injury and Restores Electrophysiological Function

Advanced Science, EarlyView.
Schematic illustration of the Pluronic F127 diacrylate/gelatin methacryloyl/poly(3,4‐ethylenedioxythiophene):poly(styrenesulfonate)/celastrol hydrogel (FGPC) for localized myocardial ischemia–reperfusion injury treatment. FGPC combines sustained celastrol delivery with PEDOT:PSS‐mediated conductive support to attenuate acute oxidative/inflammatory ...
Shixin Wang, Shaojie Chen, Chengzong Li, Hongyi Cheng, Jincheng Jiao, Xiafeng Peng, Yike Zhang, Wei Sun, Feng Zhang, Chang Cui, Minglong Chen   +10 more
wiley   +1 more source

Pramipexole in addition to mood stabilisers for treatment-resistant bipolar depression: the PAX-BD randomised double-blind placebo-controlled trial

Health Technology Assessment
Background There are limited options currently recommended in National Institute for Health and Care Excellence guidelines for the treatment of bipolar depression.
Hamish McAllister-Williams, Nicola Goudie, Lumbini Azim, Victoria Bartle, Michael Berger, Chrissie Butcher, Thomas Chadwick, Emily Clare, Paul Courtney, Lyndsey Dixon, Nichola Duffelen, Tony Fouweather, William Gann, John Geddes, Sumeet Gupta, Beth Hall, Timea Helter, Paul Hindmarch, Eva-Maria Holstein, Ward Lawrence, Phil Mawson, Iain McKinnon, Adam Milne, Aisling Molloy, Abigail Moore, Richard Morriss, Anisha Nakulan, Judit Simon, Daniel Smith, Bryony Stokes-Crossley, Paul Stokes, Andrew Swain, Zoë Walmsley, Christopher Weetman, Allan H Young, Stuart Watson   +35 more
doaj   +1 more source

oguerrer/ppi: PPI release

The model of Policy Priority ...
Omar Guerrero
core   +1 more source

Classification and prediction of dengue fever from microarray samples by LDA based on PPI network [PDF]

, 2018
Modern Bioinformatics tools have a tremendous contribution in gene analysis, Protein-Protein Interaction (PPI) Network creation and Drug design. It's been a big challenge to pick out a small subset of informative data from a large microarray dataset and ...
Md. Binyamin, et al., Nahida Habib, Kawsar Ahmed   +2 more
core   +1 more source

Assessment of the Impact of the Crisis on New PPI Projects - Update 4 : New Private Infrastructure Activity in Developing Countries Recovered in the First Half of 2009 Thanks to the Electricity Sector, But the Crisis Continues to Impact Projects

, 2009
This review of new private participation in infrastructure (PPI) projects, covering the period up to June 2009, sheds some light on the recent activity and the short-term impact of the financial crisis, compared ...
World Bank
core   +1 more source

Bending‐Resistant Intimate 3D Graphene–Metal Heterojunctions for Highly Sensitive and Robust Flexible Sensors

Advanced Science, EarlyView.
A reservoir‐guided silver‐nanoparticle soldering strategy is developed for bending‐resistant 3D graphene–metal heterojunctions. Controlled hot‐plate evaporation confines conductive ink within the metal reservoir, suppressing spreading and protecting the LIG interface from deformation‐induced fracture.
Saeyoung Park, Yoo‐Kyum Shin, Na‐Kyoung Yang, Gyeong‐Hwan Park, Somi Lee, Min‐Ho Seo   +5 more
wiley   +1 more source

The role of health research charities in PPI: results of a HRCI member survey [PDF]

In late 2023, HRCI sent a survey to our members, to capture information about how they undertake and support PPI and the barriers and facilitators that they encounter. It has some overlap with a similar HRCI survey conducted in 2018. 26 members responded
Health Research Charities Ireland
core