Results 61 to 70 of about 280,167 (308)

Buenas prácticas en la enseñanza del inglés como lengua extranjera: estudiantes de Práctica Profesional I - UPNFM - Honduras

Revista Digital de Políticas Lingüísticas, 2021
La práctica profesional es un espacio formativo en la que los futuros docentes del sistema educativo hondureño muestran las competencias adquiridas durante los años de formación teórica en las aulas de la Universidad Pedagógica Nacional Francisco Morazán
Clara Elizabeth Chávez Suazo
doaj  

El hexagrama, entre el centro y la periferia crónica estesiográfica

Revista Académica Estesis, 2016
Este texto es una crónica que cuenta la experiencia del montaje final del PPI (Pro-yecto Pedagógico Integrador) Hexahedron 2015, de la Escuela Superior Tecnológica de Artes Débora Arango.
Juan Esteban Valencia
doaj   +1 more source

Deep Contrastive Learning for High‐Throughput Prediction of Drug Resistance Mutations from Sequences

Advanced Science, EarlyView.
This study presents DeepMutDTA, a deep learning framework aimed at predicting mutation‐induced changes in protein‐drug interactions and prioritizing variants potentially linked to drug resistance. Trained on large‐scale data, it incorporates SimSiam‐MuTF, a label‐aware contrastive fine‐tuning strategy that encourages separation between WT and MT ...
Xiaowen Hu, Pan Zhang, Shangqian Wu, Hao Sun, Minwei Li, Sophia Tsoka, Zizhang Sheng, Lei Deng   +7 more
wiley   +1 more source

In silico prediction of differentially expressed genes and functionally grouped networks in patients with inflamed pulp for screening pulpitis biomarkers

European Oral Research
Purpose: Pulpitis is one of the most common oral inflammatory diseases. There are many limitations in the traditional methods of diagnosing pulpitis. By replacing new diagnostic ways based on biomarkers, it is possible to quickly and accurately identify ...
Azizeh Asadzadeh, Fatemeh Shams Moattar, Azam Moshfegh   +2 more
doaj   +1 more source

Randomised controlled trial of silk therapeutic garments for the management of atopic eczema in children: the CLOTHES trial

Health Technology Assessment, 2017
Background: Atopic eczema (AE) is a chronic, itchy, inflammatory skin condition that affects the quality of life of children and their families. The role of specialist clothing in the management of AE is poorly understood.
Kim S Thomas, Lucy E Bradshaw, Tracey H Sach, Fiona Cowdell, Jonathan M Batchelor, Sandra Lawton, Eleanor F Harrison, Rachel H Haines, Amina Ahmed, Taraneh Dean, Nigel P Burrows, Ian Pollock, Hannah K Buckley, Hywel C Williams, Joanne Llewellyn, Clare Crang, Jane D Grundy, Juliet Guiness, Andrew Gribbin, Eileen V Wake, Eleanor J Mitchell, Sara J Brown, Alan A Montgomery   +22 more
doaj   +1 more source

Public procurement of innovation

Prawo Budżetowe Państwa i Samorządu, 2020
The Author deals with public procurement of innovation (PPI and PCP) introducing the meaning of this legal institution, presenting and explaining it. This goals are achieved by indicating its characteristic features, as well as paying attention to the ...
Anna Wójtowicz-Dawid
doaj   +1 more source

Clinical effectiveness and cost-effectiveness of emergency surgery for adult emergency hospital admissions with common acute gastrointestinal conditions: the ESORT study

Health and Social Care Delivery Research, 2023
Background: Evidence is required on the clinical effectiveness and cost-effectiveness of emergency surgery compared with non-emergency surgery strategies (including medical management, non-surgical procedures and elective surgery) for patients admitted ...
Richard Grieve, Andrew Hutchings, Silvia Moler Zapata, Stephen O’Neill, David G Lugo-Palacios, Richard Silverwood, David Cromwell, Tommaso Kircheis, Elizabeth Silver, Claire Snowdon, Paul Charlton, Geoff Bellingan, Ramani Moonesinghe, Luke Keele, Neil Smart, Robert Hinchliffe   +15 more
doaj   +1 more source

Phosphorylation‐Facilitated CKB Lactylation At K11 By GCN5 Enhances Creatine Kinase Activity and Mitigates Neuronal Damage After Cerebral Ischemia‐Reperfusion

Advanced Science, EarlyView.
This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan, Ruolin Zhang, Shihui Ding, Ying Feng, Tao Shen, Ziwei Wang, Wendai Bao, Ke Shui, Jun Qin, Jun Chen, Min Zhang, Zijing Ren, Dongmei Zhao, Xingrong Guo, Zhibing Ai, Xin Yang, Peiyang Zhou, Zhiqiang Dong   +17 more
wiley   +1 more source

TAVI Through the Years: A Systematic Review of Progress

Journal of Pharmacy and Bioallied Sciences
Introduction: Transcatheter Aortic Valve Implantation (TAVI) has evolved over the years and now is being used in the management of patients with symptomatic severe aortic stenosis (AS) in categories of high, intermediate, and even low operative risk ...
Sahil Ahmad, Mukhyaprana M. Prabhu, Rama Bhat, Asif Hasan, Amber Ahmad, Rida Ahmad   +5 more
doaj   +1 more source

Measuring quality in community nursing: a mixed-methods study

Health Services and Delivery Research, 2018
Background: High-quality nursing care is crucial for patients with complex conditions and comorbidities living at home, but such care is largely invisible to health planners and managers. Nursing care quality in acute settings is typically measured using
Sue Horrocks, Katherine Pollard, Lorna Duncan, Christina Petsoulas, Emma Gibbard, Jane Cook, Ruth McDonald, Lesley Wye, Pauline Allen, Pete Husband, Lizanne Harland, Ailsa Cameron, Chris Salisbury   +12 more
doaj   +1 more source