Results 41 to 50 of about 148,011 (215)

Remote Activation of Wnt Signaling and Cell Proliferation by E‐Cadherin Magnetomechanical Stimulation

Advanced Functional Materials, EarlyView.
A pioneering magnetogenetic toolkit enables non‐invasive, precise spatiotemporal modulation of intracellular Wnt/β‐catenin signaling. Functionalized magnetic nanoparticles (MNPs@E/EC15) target cellular E‐cadherins to generate localized magnetomechanical forces under low‐intensity magnetic fields.
Christian Castro‐Hinojosa, Pablo Martínez‐Vicente, Lucía G. Recaredo, Susel Del Sol‐Fernández, Pilar Gomollón‐Zueco, Yilian Fernández‐Afonso, Raluca M. Fratila, María Moros   +7 more
wiley   +1 more source

The CIRCLE Care Home Guide: A Co‐Designed Resource on LGBTQ+ Inclusion for Care Homes

Health Expectations
Background Many older LGBTQ+ people still face discrimination in care home settings, and many care home staff do not have the knowledge required to provide LGBTQ+ inclusive care.
Jolie R. Keemink, John Hammond, Grace Collins, Joseph Price, Martin Wells, Sallie Johnson, Susan A. Rugg, Mike Parish, Andrew King, Kathryn Almack   +9 more
doaj   +1 more source

Adapting Laser Ablation Models from Simulation to Experiment: A Transfer Learning Approach for Stainless Steel, Silicon and Aluminum

Journal of Manufacturing and Materials Processing
Ultrashort Pulse Laser (USPL) ablation is a versatile manufacturing process, but predicting its outcomes across different materials often requires extensive and costly experimentation.
Javier F. Troncoso, Beatriz Blanco-Filgueira, Vanessa Alvear-Puertas, Marta Gallego-Vázquez, Sara Vidal, Tamara Delgado, Céline Petit, David Bruneel, Pablo Romero, Santiago Muiños-Landin   +9 more
doaj   +1 more source

Selective Laser Sintering and Graphitization for Mono‐Matrix Unibody Fabrication of Integrated Stereo‐Circuit and Stereo‐Fluidic Wearable Electronics

Advanced Materials, EarlyView.
A novel selective laser sintering and graphitization (SLSG) 3D printing technology enables unibody fabrication of compacted insulating structures and conductive circuits in fluidic‐integrated wearable electronics through adaptive photonic modulation.
Li Zhang, Wing Cheung Mak
wiley   +1 more source

Tailor‐Made Protective LixAlSy Layer for Lithium Anodes to Enhance the Stability of Solid‐State Lithium–Sulfur Batteries

Advanced Materials Interfaces, EarlyView.
An intentionally added, chemically formed LixAlSy coating stabilizes the lithium–electrolyte interface in solid‐state Li–S batteries. The layer suppresses side reactions, preserves smooth charge transfer, and improves ion transport from the start. This approach offers a practical route to more durable solid‐state batteries and a clearer understanding ...
Xinyi Wang, Katja Kretschmer, Sharif Haidar, Georg Garnweitner, Daniel Schröder   +4 more
wiley   +1 more source

Hierarchically Wrinkled Silver Ink as a Platform for Fully Integrated Stretchable Electronic Systems

Advanced Materials Technologies, EarlyView.
Silver Hierarchical Responsive ink (SHRink), a universal approach for the fabrication of highly stretchable interconnects, wirings, and skin‐interfaced electrodes, is realized through low‐cost, scalable spray‐printing and transfer‐printing. The SHRink demonstrates high electrical conductivity (1.2E04 S cm−1) and large stretchability (235% max fracture ...
Junye Li, Hao Wang, Xinlei Chen, Mehmet Senel, Patrick Rwei, Sara Marmarchi, David Clymer, Blossom Sundarii Hak‐Khem, Nhi Nguyen, Chengyang Qian, Matt Thomson, Michelle Khine   +11 more
wiley   +1 more source

Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis

Advanced Science, EarlyView.
Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang, Jianhua Li, Huilu Zhang, Qi Qin, Yichen Huang, Xiaofan Tian, Chao Sun, Binbin Li, Zhengxin Wang, Xin Zhang   +9 more
wiley   +1 more source

Identification of the Potential Prognosis Biomarkers in Hepatocellular Carcinoma: An Analysis Based on WGCNA and PPI

International Journal of General Medicine, 2021
Junting Huang,1,* Yating Zhan,1,* Lili Jiang,1,* Yuxiang Gao,1,* Binyu Zhao,1,* Yuxiao Zhang,1 Wenjie Zhang,1 Jianjian Zheng,1 Jinglu Yu2,3 1Key Laboratory of Diagnosis and Treatment of Severe Hepato-Pancreatic Diseases of Zhejiang Province, The First ...
Huang J, Zhan Y, Jiang L, Gao Y, Zhao B, Zhang Y, Zhang W, Zheng J, Yu J   +8 more
doaj  

Gonadotropin‐Inhibitory Hormone (GnIH) and Its Receptor GPR147 Mediates Acute Stress‐Induced Activation of the Locus Coeruleus‐SAM Axis

Advanced Science, EarlyView.
ABSTRACT Gonadotropin‐inhibitory hormone (GnIH, also known as RFamide‐related peptide‐3, RFRP‐3) is a hypothalamic neuropeptide that regulates vertebrate reproduction via its receptor GPR147. Although GnIH is known to mediate stress‐induced reproductive suppression, its role in broader stress responses remains unclear.
Jiani Zhang, Hongyu Zhu, Wenqi Wang, Bingqian Shen, Yuanyuan Xin, Xingxing Song, Xuanyi Lu, Lixuan Li, Siting Chen, Xiaochen Zhang, Jialing Zeng, Haodong Zheng, Jianlong Lao, Ke Peng, Yixian Wei, Jiaming Zheng, Chuanhuo Hu, Xiaoye Wang, Xun Li   +18 more
wiley   +1 more source

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

Advanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang, Qiang Chen, Aihua Jin, Xiaoqi Yang, Hui Zhou, Weiquan Gong, Jin Cheng, Jun Dai, Minjin Wang, Meihua Piao, Yuanyi Wang, Nan Zhou   +11 more
wiley   +1 more source