Results 71 to 80 of about 1,374,744 (197)

Optimisation sous contrainte de fiabilité d une coque imparfaite [PDF]

, 2011
National audienceSee http://hal.archives-ouvertes.fr/docs/00/59/27/95/ANNEX/r_S5P52J4K ...
Bourinet, J.-M., Cazuguel, Mikaël, Dubourg, Vincent, Sudret, Bruno   +3 more
core  

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Détection et prédiction de défaillances dans un parc d'éoliennes à l'aide de réseaux bayésiens [PDF]

, 2016
National audienceDans le domaine de la production d'énergie éolienne, une des pistes les plus promet-teuses pour la maîtrise des coûts en phase opérationnelle passe par la prédiction et la détection précoce des défaillances.
Ed-Dahmouni, Bouthayna, Gherasim, Toader, Leray, Philippe   +2 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Régression semi-supervisée à sortie noyau pour la prédiction de liens [PDF]

, 2011
National audienceNous abordons le problème de la prédiction de liens comme une tâche d'apprentissage d'un noyau de sortie par régression à sortie noyau semi-supervisée.
Brouard, Celine, d'Alché-Buc, Florence, Szafranski, Marie   +2 more
core   +2 more sources

Segmentation d'Images Texturées Couleur à l'aide de modèles paramétriques pour approcher la distribution des erreurs de prédiction linéaires

, 2011
International audienceWe propose novel a priori parametric models to approximate the distribution of the two dimensional multichannel linear prediction error in order to improve the performance of color texture segmentation algorithms.
Alata, Olivier, Burie, Jean-Christophe, Fernandez-Maloigne, Christine, Moussa, Ahmed, Qazi, Imtnan-Ul-Haque   +4 more
core   +2 more sources

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Étude comparative de techniques de lifting orientées sur des contenus synthétiques représentant des structures rectilignes [PDF]

, 2009
National audienceLes limites de la transformées en ondelettes pour représen- ter des contours d'orientation quelconques sont connues. De nouvelles représentations orientées ont été définies à partir de différentes techniques de lifting.
Barba, Dominique, Jeannic, Guillaume, Ricordel, Vincent   +2 more
core   +1 more source