Results 91 to 100 of about 2,255,048 (250)
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
, 2012 National audienceCet article porte sur la prévention situationnelle, une politique de sécurité qui consiste à aménager l'espace pour réduire la probabilité du passage à l'acte délinquant, et plus précisément sur les usages de la prévention situationnelle
Bonnet, François
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Apports de la psychologie positive dans la prévention des risques professionnels
Revue des Sciences Humaines, 2022 Cet article vise à déterminer les apports de la psychologie positive pour construire un environnement de travail sain et serein, en appliquant les conditions du bien-être en milieu du travail dans le but de réduire et prévenir les risques ...
Meriem ZAIBET
doaj
Le commissaire aux comptes et la prévention des difficultés des entreprises en droit marocain
Journal d’Economie, de Management, d’Environnement et de Droit, 2019 Avant le passage du droit de la faillite au droit des entreprises en difficultés, l’idée de prévention ne faisait pas partie des objectifs dévolus au droit marocain.
Ilyass GORFTI
doaj +1 more source
Composition pour retarder l'initiation tumorale de cellules cancereuses chez un mammifère à risque [PDF]
, 2010 La présente invention concerne une composition préventive antitumorale comprenant une quantité pharmaceutiquement efficace d\u27au moins un antagoniste du récepteur AT2 de l\u27angiotensine II pour son application comme médicament afin de prévenir le ...
D. Henrion, N. Clere, S. Faure
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source