Results 111 to 120 of about 2,300,230 (246)

Geographical risks in the touristic region of Tusnad-Balvanyos [PDF]

Cinq Continents, 2011
Des risques géographiques dans la zone touristique Tușnad-Balvanyos. Les régions volcaniques représentent un élément d’intérêt majeur tant pour les spécialistes, du point de vue de l’étude de diverses caractéristiques, que pour les touristes qui ...
ANA-MARIA TALOS
doaj  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

La prévention médicale

, 2000
Tubiana Maurice. La prévention médicale. In: Raison présente, n°136, 4e trimestre 2000. Mythologies du XXIè siècle. pp.
Tubiana, Maurice
core   +1 more source

Impact de la consommation de cannabis sur le rendement scolaire des élèves du niveau secondaire : étude de cas menée à l’Institut Kitoko, Cité du Kwilu, République Démocratique du Congo.

Revue des Sciences de la Santé
Cette étude examine l’impact de la consommation de cannabis sur le rendement scolaire des élèves de l’Institut Kitoko, situé dans le secteur de Kwenge, province du Kwilu, en République Démocratique du Congo.
Senghor LUSASI, Jean Jacques NGIMBI KISAKA, Emery LUZOLO KAFINGA, Leyka BASUA BABINTU MUKANDU   +3 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Formation * Prévention de la radicalisation

, 2018
Offres de formation des praticiens à la prévention de la radicalisation. La liste peut être complétée en écrivant à radicalisations@gmail.com. Formation trimestrielle et gratuite à la prévention de la radicalisation (CIPDR, France) Prévenir les ...
Jeanne Pawella
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Les départs précoces des pâtissiers salariés de l'artisanat : comprendre pour agir en prévention

, 2016
National audienceLe départ précoce de la plupart des pâtissiers salariés de l’artisanat, survenant bien avant l’âge légal de la retraite, constitue à la fois un paradoxe et un défi de prévention en santé au travail.
Lapoire-Chasset, Mireille, Pichene-Houard, Anne, Gaudart, Corinne, Claudon, Laurent, Martel, L., Volkoff, Serge   +5 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source