Results 131 to 140 of about 2,327,140 (248)

Le syndrome du bébé secoué: pertinence des programmes de prévention et impact sur les soins infirmiers : une revue de littérature étoffée [PDF]

, 2014
Le syndrome du bébé secoué (SBS) touche 15 à 40 enfants sur 100'000 âgés de moins de douze mois (Barlow & Minns, 2000). Les pleurs du nourrisson et la frustration qu’ils peuvent engendrer sont souvent la cause de cette maltraitance.
Baeriswyl, Martine, Bulliard, Corinne, Curty, Lara   +2 more
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Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Dynamic Prevention in Short Term Insurance Contracts [PDF]

This paper looks at the dynamic properties of insurance contracts when insurers have better technology at preventing catastrophic losses than the insured. The prevention technology is owned by the insurers and is permanent. If long-term contracts are not
Karine Gobert, M. Martin Boyer
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Les figures diversifiées des consultants et experts en prévention des RPS [PDF]

, 2014
National audienceL’objectif de cet article est d’analyser l’activité des consultants et experts en prévention des risques psychosociaux (RPS), acteurs décisifs de plus en plus mobilisés.
Chakor, Tarik, Massot, Christophe
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Prévention des maladies et promotion de la santé: propositions pour une stratégie vaudoise [PDF]

, 2010
Ce document présente un plan de prévention pour le Canton de Vaud (version octobre 2007). Ce plan concentre ses efforts sur la prévention de quelques maladies (infarctus du myocarde, accident vasculaire cérébral, diabète, cancer colorectal, cancer du ...
Heiniger, Martine, Paccaud, Fred
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Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

News from the Archives / Nouvelles des Archives [PDF]

, 2020

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TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Le manque d’équité dans le partage du pouvoir à l’origine des conflits. Analyse et perspectives [PDF]

Revue de l'UKA
Cet article propose la façon dont les responsabilités politiques doivent être partagées et cela dans le respect équitable de la géopolitique ou représentativité afin d’éviter les conflits inutiles ou du moins les minimiser.
Jean-Claude MUZEMBE MUFUNGU
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