Results 121 to 130 of about 2,290,098 (252)
Le tourisme sexuel en Thaïlande : une prostitution entre misère et mondialisation
Téoros, 2003 Près de neuf millions de touristes ont visité la Thaïlande en l’an 2000, parmi lesquels 65 à 70 % sont des hommes. Malgré d’intenses campagnes médiatiques de sensibilisation contre le tourisme sexuel et nombre de batailles judiciaires à l’encontre des ...
Franck Michel
doaj
Co-operation in Health and Safety: A Game Theory Analysis [PDF]
, 2003 [Excerpt] “Health and safety managers face complex challenges in today’s production environments. They are confronted with increasingly flexible, autonomous and polyvalent contexts.
Nadeau, Sylvie
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
A experiência com a Metodologia IRDI em creches: pré-venir um sujeito
Revista Latinoamericana de Psicopatologia FundamentalA Metodologia IRDI é um dispositivo de avaliação e acompanhamento de bebês de zero a 18 meses na sua constituição psíquica. Foi construído a partir de quatro operações constitutivas: suposição do sujeito, estabelecimento da demanda, alternância presença ...
Andrea Gabriela Ferrari +3 more
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Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Institutional Evolution, static and dynamic approaches in assessing performance related to development goals [PDF]
1. The Resocot Projet is a research project which brought together teams of researchers from the North and Africa, not all of which were familiar with the theoretical approach used at the outset.
Michel Fok, Sophia Tazi
core
Evaluation des activités de prévention du VIH/sida auprès des clients de la prostitution en Suisse [PDF]
, 2007 Dans le cadre du programme national VIH/sida 2004-2008, l'Office fédéral de la santé publique a identifié les clients de la prostitution comme un public-cible de la prévention.
Balthasar, Hugues +1 more
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Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Paix et Sécurité InternationalesL’Afrique est confrontée à une typologie diversifiée de conflits fonciers et, l’Union Africaine a adopté des directives foncières dans la perspective qu’elles contribuent significativement à la prévention des conflits fonciers. Cependant,
Ladislas Nze Bekale
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