Results 151 to 160 of about 2,290,098 (252)

The Prevention of Heart Failure Risk Assessment and Early Intervention along the Cardiovascular Continuum. [PDF]

Curr Heart Fail Rep
Grossmann E, Schilling HL, Magnussen C.
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Correction: Physical activity barriers, facilitators, and preferences in primary and tertiary prevention of breast cancer: a French national observational study. [PDF]

J Cancer Surviv
Fournier B, Delrieu L, Vallance J, Phillips S, Noh H, Gouez M, Herman F, Hamy-Petit AS, Seintinelles Research Network, Perol O, Reyal F, Fervers B.   +11 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Unravelling progress: how US foreign aid cuts undermine global efforts to end violence against women. [PDF]

BMC Public Health
Stern E, Doyle K, Levtov R, Heise L.
europepmc   +1 more source

Avis du 31/07/2018 révisé le 23/10/2018 de l'Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES) relatif à " l'analyse de la stratégie de lutte anti-vectorielle (LAV) mise en oeuvre à La Réunion depuis 2017 ". [PDF]

, 2018
Baldet, Thierry, Carnevale, Pierre, Devillers, James, Dupé, Sandrine, Noël, Harold, Roiz Pereda, David   +5 more
core  

Analyse de la prévention du VIH et des IST dans le canton de Genève, vue à travers le prisme du nouveau Programme national VIH et autres IST 2011-2017 [PDF]

, 2012
Almedal, Calle, Frey, Kathrin, Gavilanes, Amanda, Kübler, Daniel   +3 more
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Supported implementation of tailored hospital fall prevention interventions: a protocol for the PROTECT stepped wedge type I hybrid effectiveness-implementation trial. [PDF]

BMJ Open
McLennan C, Hassett L, Tilden W, Naganathan V, Haynes A, Jennings M, Ni Chroinin D, Richards B, Hallahan A, Biswas RK, Kwok W, McVeigh T, Heppleston E, Jackson D, Nayak V, Delaney S, Howard K, Pinheiro M, Macpherson A, Rayner J, Hill AM, Haines T, Sherrington C.   +22 more
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source