Results 181 to 190 of about 101,816 (263)

A Deep Learning-Driven Framework Integrating Organoid-Based Functional Validation Identifies Universal Neoantigens from Recurrent Glioma Mutations. [PDF]

Cancer Res
Wang C, Sun T, He Y, Yu M, Pan CQ, Hu H, Sun Y, Wang D, Cui Z, Zhang J, Zhai Y, Shi Z, Li Z, Xu M, Oh YT, Jiang T, Xu Z, Li G, Zhang J, Zhang W.   +19 more
europepmc   +1 more source

Local Polarization Unit Engineering Enables Ultrahigh Energy Density in NBT‐Based High‐Entropy Ceramic Capacitors

Advanced Science, EarlyView.
Herein, we demonstrate a breakthrough in dielectric energy storage by engineering local polarization units in high‐entropy multilayer ceramic capacitors (MLCCs). The optimized MLCCs achieve an ultrahigh recoverable energy density of 18.2 J cm−3 with 91% efficiency, coupled with exceptional thermal stability and fatigue resistance.
Shiyu Zhou, Yucheng Zhou, Linhai Li, A. Pelaiz‐Barranco, Xuefeng Chen, Genshui Wang, Yiwei Chen, Rongjiang Wang, Konstantin Nefedev, Tengfei Hu, Dawei Wang, Tongqing Yang   +11 more
wiley   +1 more source

Identification and credentialing of patient-derived xenograft models of invasive lobular carcinoma. [PDF]

Dis Model Mech
Hooda J, Atkinson JM, Shah OS, Yates M, Brown DD, DeBerry M, Cairo S, Schiavini P, Tsai HW, Zipeto M, Bhargava R, Oesterreich S, Lee AV.   +12 more
europepmc   +1 more source

Mn‐Induced Support Stabilization and Ir Electronic Activation Enable Acid‐Stable, Low‐Loading IrO2 Water Oxidation

Advanced Science, EarlyView.
This study introduces a dual‐regulation strategy utilizing a Mn‐doped Co3O4 support to enhance the activity and stability of low‐loading IrO2 catalysts for acidic water oxidation. Mn induces strong Mn─O covalency to reinforce the spinel lattice and activates Ir sites via interfacial electron transfer.
Zhe Liu, Guoxin Ma, Shixiang Yu, Rui Jin, Fei Wang, Xinxin Wen, Mengxin Chen, Yani Ding, Jia Liu, Xinkai Guo, Diab Khalafallah, Hassan Fouad, Xiao Ren, Siwei Li   +13 more
wiley   +1 more source

Efficacy and safety of PARP inhibitor maintenance therapy in elderly ovarian cancer patients: a real-world single-center retrospective cohort study. [PDF]

Front Oncol
Lu J, Song X, Zhang C, Zhu Y, Yang H, Li Y.   +5 more
europepmc   +1 more source

Flexoelectricity in Photoconversion: Fundamentals, Materials, and Outlooks

Advanced Science, EarlyView.
Mechanical bending of a flexible cantilever induces a strain gradient in the photoactive material. The resulting flexoelectric field couples with photovoltaic and photoconductive effects, modulating charge generation, separation, and collection. A comparative analysis of oxide perovskites, halide perovskites, and two‐dimensional materials is presented,
Xiang Huang, Feng Li, Rongkun Zheng
wiley   +1 more source

Association between self-purchased medication use and gastric disease among Chinese adults: a cross-sectional analysis based on CHARLS 2018 data. [PDF]

BMC Public Health
Hou HY, Wang Y, Zuo PX, Yang L, Yan X, Wei J, Jing YJ, Zhang N, Wang J.   +8 more
europepmc   +1 more source

Targeting PLD3 Reverses the Immunosuppressive Niche by Reprogramming Tumor‐Associated Macrophages and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin, Qiong Li, Xuemei Xu, Yuhan Wu, Yin Zhu, Jieqiong Wu, Yuan Fang, Qiubei Chen, Shuyang Wang, Jiang Yu, Yaping Ye, Hongli Jiao   +11 more
wiley   +1 more source

Development and validation of a machine learning-based early warning model for carbapenem-resistant <i>Klebsiella pneumoniae</i> bloodstream infections using non-carbapenem susceptibility profiles. [PDF]

Front Microbiol
Song J, Bai Y, He S, Ji J, Chen Y, Xiao Y.   +5 more
europepmc   +1 more source

Noninvasive Characterization of Tumor Heterogeneity in HNSCC: From Clinical Utility to Biological Correlates

Advanced Science, EarlyView.
This study establishes a CT‐based radiomics framework to quantify intratumoral heterogeneity (ITH) in HNSCC. Using unsupervised clustering, tumor ROIs and VOIs are analyzed to calculate 2D/3D ITH scores. The score shows strong predictive value for prognosis and immunotherapy response, and is associated with tumor metabolism and immune microenvironment,
Xinwei Chen, Rui Liu, Yuan Zhou, Yin Xiao, Chengmin Feng, Lin Chen, Yanshi Li, Mengna Wang, Zhaobo Cheng, Yuxi Luo, Long Liu, Lijing Niu, Yue Xiang, Juan Peng, Guohua Hu, Min Pan   +15 more
wiley   +1 more source