Results 191 to 200 of about 101,816 (263)

PGK1 Suppresses CD8+ T Cell‐Mediated Antitumor Immunity Through CCL2/CCR2/Tumor‐Associated Macrophages Axis in Hepatocellular Carcinoma

Advanced Science, EarlyView.
PGK1 in tumor cells upregulates CCL2 expression through activation of the AKT/GSK‐3β/β‐catenin signaling axis, thereby promoting the recruitment and M2 polarization of TAMs and ultimately impairing the infiltration and activation of CD8+ T cells within the HCC tumor microenvironment. ABSTRACT Patients with advanced hepatocellular carcinoma (HCC) have a
Xi Liu, Jianpeng Liu, Zhihao Zhang, Xizhi Yu, Junjie Qian, Limin Ding, Qinchuan Wu, Zhe Yang, Xing‐Yu Luo, Xinjiang Ding, Rong Su, Xiaobo Yu, Yiting Qiao, Shengyong Yin, Haiyang Xie, Lin Zhou, Yuanxing Liu, Shusen Zheng   +17 more
wiley   +1 more source

Development and validation of a risk prediction model for piecemeal resection during endoscopic resection of gastric GISTs. [PDF]

Surg Endosc
Zang F, Feng Y, He B, Wang Z, Ma C, Xu X, Chen J, Liu L.   +7 more
europepmc   +1 more source

How Advanced Artificial Intelligence Technologies Shape Drug–Drug and Drug–Target Interaction Modeling

Advanced Science, EarlyView.
This review explores the convergence of artificial intelligence technologies in modeling drug–drug and drug–target interactions. By evaluating advanced feature engineering, architectural innovations, and learning paradigms reveals shared evolutionary trends and critical challenges, such as cold‐start settings and shortcut learning.
Xin Sun, Tong Wang
wiley   +1 more source

LATEST TRENDS IN FORMING THE PR INDUSTRY WITH THE USE OF DIGITAL PR TOOLS IN THE INFORMATION SOCIETY

Perspectives. Socio-political journal
Liudmyla Vitaliivna Chernii, Natalia Volodymyrivna Khomenko, Vitaliy Grigorovich Chugaevsky   +2 more
openaire   +1 more source

Cheatomaly: weakly supervised video anomaly ranking for exam cheating detection using vision transformers. [PDF]

Front Big Data
Alaoui Mrani EM, Bouayad A, Fardousse K.
europepmc   +1 more source

Bias‐Engineered Synthetic Antiferromagnets Hosting Sub‐20 nm Zero‐Field Skyrmions at Room Temperature

Advanced Science, EarlyView.
A fully compensated synthetic antiferromagnet (SAF) multilayer exhibits a uniform state at zero field, without skyrmions. We use a SAF bias system to provide RKKY‐mediated exchange bias to the SAF multilayer, promoting zero‐field skyrmion stabilization and polarity control.
Emily Darwin, Riccardo Tomasello, Reshma Peremadathil Pradeep, Mario Carpentieri, Giovanni Finocchio, Hans J. Hug   +5 more
wiley   +1 more source

Digital Intelligence in Dental Education: A Bibliometric Analysis. [PDF]

Int Dent J
Guo R, Zhang Y, Li W, Liu D, Hu W.
europepmc   +1 more source

IKKβ and USP28 Regulate HEY1 Stability to Promote Cancer Stemness and Immune Evasion in Hepatocellular Carcinoma

Advanced Science, EarlyView.
The uncovered IKKβ‐USP28‐HEY1 axis fuels cancer stemness and immune evasion in hepatocellular carcinoma. USP28 deubiquitinates HEY1 upon IKKβ‐mediated phosphorylation, conferring PD‐1/PD‐L1 blockade resistance. Pharmacological inhibition of USP28 sensitizes resistant tumors to anti‐PD‐1 immunotherapy, revealing a promising therapeutic strategy ...
Na Shao, Lin Zhang, Gufang Shen, Yangfan Lv, Tianshu Fang, Ya Cao, Qiongyi Zhang, Feng Xu, Chungang Liu   +8 more
wiley   +1 more source

Immune checkpoint inhibitors for invasive mucinous adenocarcinoma: A case series. [PDF]

Oncol Lett
Kato T, Mitsumura T, Tsuboi E, Nakahama H, Takahashi Y, Nei Y, Hanada S, Miyamoto A, Uruga H, Fujii T, Tamaoka M.   +10 more
europepmc   +1 more source

Quantifying Structure–Property Relationships in Ferroelectric Polymers Toward High‐Performance Soft Robots

Advanced Science, EarlyView.
Here, we establish a quantitative relationship between the electrostriction coefficient (Q33) of FRPs and their interplanar spacing (d): Q33 = 100(Δd/d0+1) × Q33(s). Using this model, we fabricated high‐performance soft robots, including a biomimetic crawler (with a speed of 27 cm/s) and a butterfly (with a thrust‐to‐weight ratio of 0.71).
Ba Qin, Guotong Ding, Wanli Xing, Xiaoyu Yang, Wenxuan Li, Zhemin Chen, Shaobo Tan, Xiaoyong Wei, Zhicheng Zhang   +8 more
wiley   +1 more source