Results 41 to 50 of about 3,216,025 (290)

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Practical Rationality – its Nature and Operation

Studia Humana, 2019
The article presents a proposal of explanation what practical rationality is, how it works and what are its criteria. In order to define practical rationality, the author starts from the general characteristics of reason, and then in the realm or reason ...
Niemczuk Andrzej
doaj   +1 more source

What is at stake

Phenomenology and Mind, 2015
Recent events involving two symbols of ancient and modern philosophy, and two capitals of the Idea of Europe – Athens and Paris – suggest the timeliness of this issue of “Phenomenology and Mind” on Philosophy and the future of Europe.
Roberta De Monticelli
doaj   +1 more source

Anscombe on Acting for Reasons [PDF]

, 2020
This chapter discusses some of Anscombe’s contributions to the philosophy of practical reason. It focuses particularly on Anscombe’s view of what it is to act for reasons. I begin by discussing the relationship between acting intentionally and acting for
Singh, Keshav
core  

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

On the needs of theoretical and practical reason

Voluntas, 2020
Thinking beyond the limits of possible empirical knowledge requires a subjective reason for legitimizing its judgments. According to Kant, this lies in the feeling of a "need for reason", which for its part (in contrast to "non-rational" urge) must be ...
Christian Hamm
doaj   +1 more source

Personal Identity and Practical Reason: The Failure of Kantian Replies to Parfit [PDF]

, 2008
: This essay examines and criticizes a set of Kantian objections to Parfit's attempt in Reasons and Persons to connect his theory of personal identity to practical rationality and moral philosophy. Several of Parfit's critics have tried to sever the link
Blackburn, Blackburn, Hume, Jonny Anomaly, Kant, Korsgaard, Korsgaard, Korsgaard, Nagel, Nozick, Rawls, Sidgwick, Williams, Williams   +13 more
core   +3 more sources

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

On Act-Types and Act-Tokens: or, the Distinction between Practical Reason and Practical Judgment in Kant

Journal of Modern Philosophy
While there is an extensive literature on Kant’s conception of practical reason, there is comparatively little on his conception of practical judgment. In addition, commentators have yet to take up the question of what the distinction between practical ...
Nicholas Dunn
doaj   +2 more sources

Practical Reason, Habit, and Care in Aristotle

Praxis Filosófica, 2016
En las últimas décadas, la interpretación de la teoría de la acción de Aristótelesha tendido hacia una postura intelectualista, según la cual la razón está acargo de establecer los fines de las acciones. Un resurgimiento del antiintelectualismo,según el
Juan Pablo Bermúdez
doaj   +1 more source