Results 81 to 90 of about 1,025,961 (289)

Recent Work on Internal and External Reasons [PDF]

open access: yes, 2017
This paper examines some recent arguments for internalism that (i) appeal to an analogy between practical and theoretical reasons, (ii) look toward our practices of reasoning with others, or (iii) tie reasons to good deliberation.
Brunero, John
core  

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Educating for uncertainty: Integrating abductive reasoning into the public policy curriculum

open access: yesPolicy Design and Practice
Traditional quantitative policy analysis often fails to effectively address complex, uncertain, and value-laden policy challenges due to limitations rooted in data unavailability, causal complexity, and difficulty in modeling value conflicts.
M Ramesh, Michael Howlett
doaj   +1 more source

Endorsement, Reasons and Intentional Action

open access: yesTheoria, 2009
Moran’s conception of self-knowledge, in his book Authority and Estrangement, is connected to an extremely rationalistic conception of intentional action.
Josep L. Prades
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

THE PREEMINENT NECESSITY OF PRUDENCE [PDF]

open access: yesStudia Gilsoniana, 2017
Thomas Aquinas holds not only that prudence, the virtue of right practical reasoning, is necessary for living well, but emphatically asserts that it “is the virtue most necessary to human life.” This essay argues that the force of Thomas’ assertion ...
Brian Kemple
doaj  

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

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