Results 141 to 150 of about 14,777,051 (346)
The Theory and Practice of Scientific Management, by C. Bertrand Thompson [PDF]
Horace Bookwalter Drury
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Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
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Enhancing academic development practice: reclaiming academic practice wisdom [PDF]
The growing impetus for science-based or evidence-based practices in higher education are shaping conceptions of the nature and role of professional practice and raising new concerns about what it means to be adequately prepared and what it means for ...
Crawford, Karin, Morris, Gayle
core
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
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Some Account of the First Use of Sulphuric Ether by Inhalation in Surgical Practice [PDF]
George Hayward
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This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu+12 more
wiley +1 more source