Results 111 to 120 of about 66,648 (290)
Journal of Medical Internet ResearchBackgroundHealth service policy in many jurisdictions is driving greater investment into digital primary care services. While some patients and practices may benefit, there are concerns that not all are able or wish to access ...
Rachel Winder +12 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
The Fundamentals of Facilitation Practice
EDISThis publication is the first part of an Ask IFAS series on facilitation. Subsequent articles focus on planning a facilitated meeting, implementing facilitation in a meeting, and applications of facilitation in Extension. Written by Peyton N.
Peyton N. Beattie, Linda Seals
doaj
Trade Facilitation in Ethiopia: The Role of WTO Accession in Domestic Reform
Mizan Law Review, 2015 Ethiopia is one of the countries with excessive challenges in cross border trade. The high cost of doing business across borders in Ethiopia has become a major constraint. The focus of this article is trade facilitation which requires the examination of
TE Kassahun
doaj +1 more source
Overture to practical theological facilitation
Nederduitse Gereformeerde Teologiese Tydskrif, 2013 The author introduces what he calls practical theological facilitation. The metaphor and activity of facilitation is regarded as an important lens and dimension in, and to, practical theology. It is espoused not only as an approach to standing practice but in particular as a professional-vocational
openaire +2 more sources
, 2015 This study sought to investigate what constituted best practice in clinical facilitation of undergraduate nursing students from the perspectives of those who undertake this role in health care agencies.
Needham, Judith
core +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source