Results 81 to 90 of about 1,173,896 (324)

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Diretrizes para detecção precoce do câncer de mama no Brasil. II - Novas recomendações nacionais, principais evidências e controvérsias

open access: yesCadernos de Saúde Pública, 2018
Resumo: O câncer de mama é a principal causa de morte por câncer em mulheres no Brasil. As novas diretrizes para detecção precoce no Brasil foram elaboradas com base em revisões sistemáticas da literatura sobre riscos e possíveis benefícios de diversas ...
Arn Migowski   +5 more
doaj   +1 more source

Identification and Prioritization of Canadian Society of Nephrology Clinical Practice Guideline Topics

open access: yesKidney International Reports
Nephrology clinical practice guideline topics are routinely determined by clinicians and researchers, without extensive engagement of people with lived experience (PWLE) of kidney disease and their caregivers. The Canadian Society of Nephrology (CSN) Clinical Practice Guidelines Committee (CPGC) completed this modified Delphi study to incorporate ...
Tyrone G. Harrison   +9 more
openaire   +3 more sources

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Unleashing Top-of-License Registered Nurse Practice: An Integrative Review [PDF]

open access: yes, 2019
In light of a well-renowned report, “The Future of Nursing” released by the Institute of Medicine (2010), recommendations were suggested that nurses should practice at, and to, the full extent of their licensure, also referred to as top-of-license ...
Dickerson, Michelle
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Choosing and using methodological search filters : searchers' views [PDF]

open access: yes, 2015
© 2014 The authors.
Beale, Sophie   +10 more
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Multidisciplinary team approach in amputated patients care: contextualising hospital services and protocols

open access: yesCadernos Brasileiros de Terapia Ocupacional, 2018
Introduction: The Brazilian Guidelines for Attention to the Health of the Amputee brings protocols of pre-surgical assistance until post prosthetic fitting rehabilitation.
Bárbara Kons dos Santos   +4 more
doaj   +1 more source

Sustainability and institutionalization model: the case of the MPIA [PDF]

open access: yes, 2019
The present text deals in a general way the way in which from the Master in Innovative Processes in Learning (MPIA) that operates as a double degree by the Centro Universitario de Los Altos (CUALTOS) of the University of Guadalajara, in collaboration ...
Carranza Alcántar, Maria del Rocío   +3 more
core  

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