Results 181 to 190 of about 948,333 (269)

Current practice patterns among Indian neurologists in the Evaluation and management of Normal Pressure Hydrocephalus: A nationwide cross-sectional survey. [PDF]

Alzheimers Dement
Elavarasi A, Poudel S, Dash D, Fasano A, Pal P, Chowdhury D, Pandey S, Desai S, Kumar H, Kukkle PL, Kp D, Cherian A, A R, Mridula R, Agarwal P, Kumar N, Kumar A, Gomathy S, Das A, Singh RK, Vibha D, Parihar J, Tripathi M.   +22 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Assessing Practice Patterns of Antidepressant Medication and Tamoxifen Use Among Patients With Hormone Receptor-Positive Breast Cancer. [PDF]

Cancer Rep (Hoboken)
Lopetegui-Lia N, Murray A, Ondeck M, Osantowski B, Takkellapati S, Wei W, Maggiotto A, Moore HCF, Roesch E.   +8 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Patient selection, practice patterns, and perioperative outcomes for robotic splenectomy: a contemporary ACS-NSQIP analysis. [PDF]

Surg Endosc
Farooq MS, Jona A, Vargas GM, Simons RA, Miura JT, Karakousis GC, Etherington MS.   +6 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Practice Patterns and Challenges of Glaucoma Specialists in Achieving Optimal Management for Glaucoma in India: Results From a National Survey. [PDF]

Cureus
Gogate P, Paranjpe M, George R, Shah S, Chippa P, Dharwadkar S, Mathur M, Radhakrishnan O, Maskati QB, Nayak BK.   +9 more
europepmc   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Declining Bariatric Surgery Volumes and Shifting Practice Patterns: A Five-Year Analysis of Over One Million Procedures. [PDF]

Obes Surg
Wills MV, Zhu X, Elamin D, Corcelles R, Kroh M, Dang J, Strong A, Navarrete S, Mocanu V.   +8 more
europepmc   +1 more source