Results 191 to 200 of about 872,401 (268)

Current status of 5-aminosalicylic acid in Crohn's disease treatment: a nationwide survey and analysis of perspectives and practice patterns among inflammatory bowel disease physicians. [PDF]

Front Gastroenterol (Lausanne)
Li Y, Chen C, Wang C.
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Exploring midwives' practice patterns and capacity for obstetric ultrasound imaging: Towards a multicentre longitudinal materno-foetal research readiness in a low-resource setting. [PDF]

PLoS One
Piersson AD, Asakeboba PA, Quartei ST, Mendy R, Arkorful J, Akomah AB, Allorsey G.   +6 more
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

International Practice Patterns in the Surgical Management of Primary Lumbar Disc Herniation: An AO Spine Cross-Sectional Study. [PDF]

Neurospine
Ambrosio L, Muthu S, Hsieh PC, Yoon ST, Wang JC, Vadalà G, Meisel HJ, Ćorluka S, Buser Z, AO Spine Knowledge Forum Degenerative.   +9 more
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Climate change literacy and environmental stewardship in neonatal intensive care: a mixed-methods study of nursing practice patterns. [PDF]

BMC Nurs
Ramadan OME, Alshammari AM, Alruwaili AN, Elsharkawy NB, Alhaiti A, Mohamed NA.   +5 more
europepmc   +1 more source

Knowledge, training, and practice patterns in pneumatic tourniquet use among orthopedic physicians: a national cross-sectional survey. [PDF]

Arch Orthop Trauma Surg
Gündoğdu M, Gülabi D, Baysal Ö.
europepmc   +1 more source