Results 201 to 210 of about 948,333 (269)

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Clinical Practice Patterns in the Physiotherapy Management of Tension-Type Headache Among Spanish Physiotherapists. [PDF]

J Clin Med
Bravo-Vazquez A, De-La-Barrera-Aranda E, Anarte-Lazo E, Rodriguez-Blanco C, Bernal-Utrera C.   +4 more
europepmc   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Attitudes, opinions and practice patterns regarding anaesthesia providers' use of vasopressors: protocol for a multicentre mixed-methods study. [PDF]

BMJ Open
Janda AM, Mirizzi K, Athavale T, Mathis MR, Dubovoy T, Cocroft S, Chen T, Alrubaie N, Kheterpal S, Guetterman T.   +9 more
europepmc   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Practice patterns and outcomes in cancer patients developing immune checkpoint inhibitors-related AKI. [PDF]

Nephrol Dial Transplant
Blanchette PS, Reid J, Richard L, Shariff SZ, Raphael J, Earle CC, Garg AX, Kitchlu A.   +7 more
europepmc   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Post-operative practice patterns after the bidirectional Glenn surgery: a survey. [PDF]

Cardiol Young
Weinerman B, Kwon SB, Cheung EW, Park S.
europepmc   +1 more source

Surgeon preferences and practice patterns in rectopexy: Results of an international survey. [PDF]

Colorectal Dis
Gialamas E, Uhe I, Tokoto PA, Liot E, Ris F, Wexner SD, Meyer J, Meurette G, International Rectopexy Collaborative Group.   +8 more
europepmc   +1 more source

A survey of practice patterns for patient-specific quality assurance on behalf of the ESTRO dosimetry & quality assurance focus group. [PDF]

Phys Imaging Radiat Oncol
Dufreneix S, Essers M, Aspradakis MM, Wegener S, Saez J, Ventura T, Jornet N, Gerskevitsh E.   +7 more
europepmc   +1 more source