Results 51 to 60 of about 7,262,172 (236)

Developing a gender measure and examining its association with cardiovascular diseases incidence: a 28-year prospective cohort study

BMC Medicine
Background Cardiovascular diseases (CVD) are the leading cause of morbidity and mortality worldwide. Examining gender (socio-cultural) in addition to sex (biological) is required to untangle socio-cultural characteristics contributing to inequities ...
Mahée Gilbert-Ouimet, Azita Zahiriharsini, Caty Blanchette, Denis Talbot, Xavier Trudel, Alain Milot, Chantal Brisson, Peter Smith   +7 more
doaj   +1 more source

Increased aortic intima-media thickness may be used to detect macrovascular complications in adult type II diabetes mellitus patients

Cardiovascular Ultrasound, 2018
Background Carotid intima media thickness (C-IMT) and aortic IMT (A-IMT) increase in adult and pediatric patients with diabetes mellitus (DM), respectively. In both age groups IMT is used for early detection of macrovascular complications.
Ayse Selcan Koc, Hilmi Erdem Sumbul
doaj   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

Molecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever, Renske D. M. Steenbergen   +1 more
wiley   +1 more source

Predictors of medication regimen complexity and its impact on hemoglobin a1c in type 2 diabetes patients: a retrospective analysis in ambulatory care in Makkah City

Annals of Saudi Medicine
BACKGROUND: Type 2 diabetes mellitus (T2DM) is a widespread chronic disease that poses a significant management challenge due to the complexity of the associated medication regimens, which can have a considerable impact on patient outcomes.
Sarah M. Khayyat, Ruba S. Azfr Ali, Hanadi H. Alrammaal, Salwa M.S. Khayyat, Wafaa A. Alqurashi, Reemaz Alsaedi, Wejdan Alotaibi, Aseel Alahmadi   +7 more
doaj   +1 more source

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

Molecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren, Philippe Decruyenaere, Francisco Avila Cobos, Johanna Bult, Jill Deleu, Laudonia Lidia Dipalo, Hetty Hilde Helsmoortel, Eva Hulstaert, Annelien Morlion, Elena Ramos Varas, Kathleen Schoofs, Wim Trypsteen, Eveline Vanden Eynde, Hanne Van Droogenbroeck, Kimberly Verniers, Jo Vandesompele, Anneleen Decock   +16 more
wiley   +1 more source

GRADE-ADOLOPMENT of clinical practice guidelines and creation of clinical pathways for the primary care management of chronic respiratory conditions in Pakistan

BMC Pulmonary Medicine, 2023
Introduction In Pakistan, chronic respiratory conditions contribute a large burden of morbidity and mortality. A major reason for this is the lack of availability of local evidence-based clinical practice guidelines (EBCPGs) in Pakistan, particularly at ...
Russell Seth Martins, Hawra Hussain, Maryam Chaudry, Nashia Ali Rizvi, Mohsin Ali Mustafa, Bushra Ayub, Salima Saleem Aamdani, Alina Abdul Rehman, Alina Pervez, Sarah Nadeem, Rameesha Khalid, Akbar Shoukat Ali, Shayan Shahid, Ali Bin Sarwar Zubairi, Adil H. Haider, Muhammad Irfan   +15 more
doaj   +1 more source

The Effects of Human Resource Management Practices on Productivity

, 1995
Increasingly, firms are considering the adoption of new work practices, such as problem-solving teams, enhanced communication with workers, employment security, flexibility in job assignments, training workers for multiple jobs, and greater reliance on ...
Casey Ichniowski, K. L. Shaw, Giovanna Prennushi   +2 more
semanticscholar   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

Molecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink, Leon W. M. M. Terstappen, Eshwari Dathathri, Khrystany Isebia, Jaco Kraan, John Martens, Ruchi Bansal   +6 more
wiley   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

Assessing Knowledge and Attitude of Pediatricians and Pharmacists Regarding Monitoring Unbound Valproic Acid Concentration in Pediatric Patients With Hypoalbuminemia

International Journal of Clinical Practice
Conclusion: The suboptimal practice of monitoring free VPA concentrations in cases of hypoalbuminemia in pediatric settings, mainly due to lack of awareness.
Nada Safhi, Mayam Alharthi, Hanadi Alrammaal, Rahaf Ali, Naji Alsulami   +4 more
doaj   +1 more source