Results 61 to 70 of about 8,841,562 (288)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Muscular and Renal Safety of Ticagrelor with High-Intensity Statins: Retrospective Cohort Findings

Therapeutics and Clinical Risk Management
Abdullah S Alshammari,1 Amer A Shalwala,2 Mohammed A Alnuhait,1 Abdulfattah Y Alhazmi,1 Refal E Fagieha,3 Nura Bin Hallabi,1 Eyad A Alandijani,1 Mansour A Aloufi,1 Mudhhi S Alharbi,1 Reem S Alzahrani,4 Emad M Elkholy,3 Mahmoud E Elrggal,5 Abdulmalik S ...
Alshammari AS, Shalwala AA, Alnuhait MA, Alhazmi AY, Fagieha RE, Hallabi NB, Alandijani EA, Aloufi MA, Alharbi MS, Alzahrani RS, Elkholy EM, Elrggal ME, Alotaibi AS   +12 more
doaj  

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

American Academy of Orthopaedic Surgeons/American Society for Surgery of the Hand Clinical Practice Guideline Summary Management of Distal Radius Fractures

, 2022
Robin N. Kamal, Lauren M. Shapiro
openalex   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Increased aortic intima-media thickness may be used to detect macrovascular complications in adult type II diabetes mellitus patients

Cardiovascular Ultrasound, 2018
Background Carotid intima media thickness (C-IMT) and aortic IMT (A-IMT) increase in adult and pediatric patients with diabetes mellitus (DM), respectively. In both age groups IMT is used for early detection of macrovascular complications.
Ayse Selcan Koc, Hilmi Erdem Sumbul
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Psychosocial Stressors at Work and Atrial Fibrillation Incidence: An 18‐Year Prospective Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Psychosocial stressors at work, defined by the job strain and effort–reward imbalance at work (ERI) models, were shown to increase coronary heart disease risk. No previous study has examined the adverse effect of psychosocial stressors at work
Edwige Tiwa Diffo, Mathilde Lavigne‐Robichaud, Alain Milot, Chantal Brisson, Mahée Gilbert‐Ouimet, Michel Vézina, Denis Talbot, Xavier Trudel   +7 more
doaj   +1 more source

Liquid Hydroxyurea (Xromi) for Children With Sickle Cell Anemia: A New Solution Compounding Existing Problems

Pediatric Blood &Cancer, EarlyView.
Alexandra Power‐Hays, Charles T. Quinn
wiley   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source