Results 71 to 80 of about 15,704 (225)

Clinical, Radiologic and Cytologic Predictors of Malignancy in Pediatric Thyroid Nodules: Insights From a 26‐Year Cohort Study

Head &Neck, EarlyView.
ABSTRACT Introduction Thyroid nodules are less common but more often malignant in pediatric patients than in adults. Our objectives were to study the features of benign vs. malignant thyroid nodules in a large pediatric patient cohort. Methods Retrospective observational cohort study. Consecutive patients aged 0.01–17.9 years at evaluation between 1997–
Maxime Gest‐Laurent, Adrien Nguyen Quoc, Christine Lefevre, Laura González‐Briceño, Caroline Thalassinos, Isabelle Flechtner, Dulanjalee Kariyawasam, Yamina Dassa, Magali Viaud, Dinane Samara‐Boustani, Graziella Pinto, Hervé Monpeyssen, Sabine Sarnacki, Vincent Couloigner, Michel Polak, Athanasia Stoupa   +15 more
wiley   +1 more source

Prader-Willi Syndrome. About a Case [PDF]

, 2021
Prader-Willi syndrome is a rare genetic disease, characterized by hypothalamic-pituitary anomalies, which presents with severe hypotonia during the neonatal period and the first two years of life, with hyperphagia with a high risk of developing morbid ...
Carlos Enrique Cruz Carrazana, Claudia García Carrazana   +1 more
core   +1 more source

Maternal influenza vaccination during pregnancy and risk of autism spectrum disorder in the offspring

JCPP Advances, EarlyView.
Abstract Background Vaccination has been proposed as a potential risk factor for autism spectrum disorder (ASD), contributing to public hesitancy and mistrust toward immunization. Influenza vaccination during pregnancy is considered safe and effective in preventing serious maternal complications and adverse birth outcomes associated with influenza ...
Shahar Neeman, Maor Hemo, Gal Meiri, Dorit Shmueli, Idan Menashe   +4 more
wiley   +1 more source

Prader-Willi Syndrome - Characteristics, Communication, Speech and Language [PDF]

, 2023
Prader-Willijev sindrom složeni je genetski poremećaj iz skupine rijetkih bolesti. Nastaje zbog nedostatka izražaja očevih gena na 15. kromosomu. Pojavnost se procjenjuje u omjeru od 1:12.000 do 1:15.000.
Vučinac Zelić, Nevena
core   +2 more sources

Circulating Irisin in Children and Adolescents With Prader-Willi Syndrome: Relation With Glucose Metabolism

Frontiers in Endocrinology, 2022
Irisin is a myokine involved in the browning of white adipose tissue and regulation of energy expenditure, glucose homeostasis and insulin sensitivity. Debated evidence exists on the metabolic role played by irisin in children with overweight or obesity,
Stefania Mai, Danilo Fintini, Chiara Mele, Alessio Convertino, Sarah Bocchini, Graziano Grugni, Gianluca Aimaretti, Roberta Vietti, Massimo Scacchi, Massimo Scacchi, Antonino Crinò, Paolo Marzullo, Paolo Marzullo   +12 more
doaj   +1 more source

Functional constipation in children and young adults with Prader–Willi syndrome

JPGN Reports, EarlyView.
Abstract Objectives Prader–Willi Syndrome (PWS) is characterized by hyperphagia, endocrinopathies, and gastrointestinal abnormalities. Clinical concerns about constipation and fecal incontinence (FI) are common, but no studies to date have clear data on functional defecation disorders in children with PWS.
Melinda J. Pierce, Isabella Niu, Lusine Ambartsumyan, Parisa Salehi   +3 more
wiley   +1 more source

Prader-Willi Syndrome: Diagnostic Criteria [PDF]

, 1993
Diagnostic criteria for Prader-Willi syndrome (PWS), developed by consensus of seven clinicians in consultation with experts, are reported from the University of Washington, Seattle, and six additional ...
J Gordon Millichap
core   +1 more source

Current Treatments for Patients with Genetic Obesity

JCRPE, 2023
Obesity derives from impaired central control of body weight, implying interaction between environment and an individual genetic predisposition. Genetic obesities, including monogenic and syndromic obesities, are rare and complex neuro-endocrine ...
Nathan Faccioli, Christine Poitou, Karine Clément, Béatrice Dubern   +3 more
doaj   +1 more source

SURMOUNT‐REAL UK: A Pragmatic Randomized Clinical Trial to Assess the Effectiveness of Tirzepatide in Adults With Obesity

Obesity, EarlyView.
ABSTRACT Objective SURMOUNT‐REAL UK will evaluate the effectiveness of tirzepatide when offered in addition to standard‐of‐care (SoC) in adults with Class I obesity (BMI ≥ 30 and ≤ 34.9 kg/m2) and without diabetes in a UK primary care setting. Methods A 5‐year, phase 4, multicenter, open‐label, pragmatic randomized clinical trial is enabled through ...
Martin K. Rutter, Julie Mount, J. Martin Gibson, Joanne Webb, Cheryl Marler, Catherine Reed, Mugdha Gore, Wenyu Ye, Elisa Gomez Valderas, John Wilding, Naveed Sattar, Melanie J. Davies, Kamlesh Khunti, Richard Haynes, Rachel L. Batterham   +14 more
wiley   +1 more source

Elsődleges genetikai vizsgálat Prader–Willi-szindróma igazolására = Rapid first-tier genetic diagnosis in patients with Prader–Willi syndrome [PDF]

, 2018
Absztrakt: Bevezetés: A nemzetközi szakirodalmi adatok alapján az SNRPN génlocus promoter régiójának DNS-metilációs vizsgálata jelenleg a legérzékenyebb és leghatékonyabb kezdeti lépés a
Buiting, Karin, Sallai, Ágnes, Dóra Török, Buiting K, Péter Hollósi, Fekete, György, Haltrich, Irén, Bálint Péterfia, Andrea Luczay, Szabó, András, Horsthemke B, Karin Buiting, György Fekete, Ács, Orsolya Dóra, Luczay, Andrea, Török, Dóra, Ágnes Sallai, Orsolya Dóra Ács, Bernhard Horsthemke, András Szabó, Péterfia, Bálint, Horsthemke, Bernhard, Hollósi, Péter, Irén Haltrich   +23 more
core   +1 more source