Results 51 to 60 of about 6,694,831 (167)

Concomitant cartilage restoration does not demonstrate consistent additional clinical benefit in medial patellofemoral ligament reconstruction: A systematic review

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose This review specifically evaluates whether the presence of cartilage lesions, or their surgical treatment, modifies the clinical benefit of medial patellofemoral ligament (MPFL) reconstruction. Methods A systematic review was conducted following PRISMA (Preferred Reporting Items for Systematic Reviews and Meta‐Analyses) guidelines ...
Dave Osinachukwu Duru, Djamel Wade, Marc Daniel Bouchard, Prushoth Vivekanantha, Shahbaz S. Malik, Nathan Wm Skelley, Bryson P. Lesniak, Darren de Sa   +7 more
wiley   +1 more source

Acupuncture in Seasonal Allergic Rhinitis (ACUSAR) - Design and Protocol of a Randomised Controlled Multi-Centre Trial [PDF]

, 2010
Background: We report on the study design and protocol of a randomised controlled trial (Acupuncture in Seasonal Allergic Rhinitis, ACUSAR) that investigates the efficacy of acupuncture in the treatment of seasonal allergic rhinitis (SAR).
Witt, Claudia M., Wegscheider, Karl, Roll, S., Willich, Stefan N., Pfab, F., Witt, C.M., Linde, K., Willich, S.N., Brinkhaus, B., Roll, Stephanie, Ortiz, Miriam, Reinhold, T., Linde, Klaus, Niggemann, B., Brinkhaus, Benno, Reinhold, Thomas, Hummelsberger, Josef, Ortiz, M., Hummelsberger, J., Wegscheider, K., Pfab, Florian, Niggemann, Bodo, Irnich, Dominik, Irnich, D., Brinkhaus, Benno;Witt, Claudia M.;Ortiz, Miriam;Roll, Stephanie;Reinhold, Thomas;Linde, Klaus;Pfab, Florian;Niggemann, Bodo;Hummelsberger, Josef;Irnich, Dominik;Wegscheider, Karl;Willich, Stefan N., Brinkhaus, B;Witt, CM;Ortiz, M;Roll, S;Reinhold, T;Linde, K;Pfab, F;Niggemann, B;Hummelsberger, J;Irnich, D;Wegscheider, K;Willich, SN   +25 more
core   +1 more source

Hamstring graft remodelling after ACL reconstruction is slower in paediatric population compared to adults

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Anterior cruciate ligament (ACL) injuries are increasing in children and adolescents and reconstruction (ACLR) is now frequently performed in this population. Paediatric patients remain at higher risk of reinjury, possibly due to delayed graft remodelling.
Caroline de Pesters, Nicolas Vari, Emilie Bérard, Estelle Maupoint, Linda Staali, Marie Faruch, Etienne Cavaignac, Franck Accadbled   +7 more
wiley   +1 more source

Assessment of outcome in clinical trials in mild Alzheimer 19s disease: urgent time for a rethink? [PDF]

, 2013
Introduction: A major barrier for clinical trials in Alzheimer's disease is the lack of sensitive clinical endpoints for the early stages. Until recently, regulatory agencies have required demonstration of improvement in two disease domains, cognition ...
McGoldrick, S., Duffy, Fiona, McGoldrick, Susan, Reynish, Emma, Kelly, Fiona, Morrison, Y., Wilson, L., Bennett, Crispin, Wilson, J T Lindsay, Bennett, C., Morrison, Yvonne, Duffy, F., Reynish, E.   +12 more
core  

Mesh shrinkage and pain in laparoscopic ventral hernia repair: a randomized clinical trial comparing suture versus tack mesh fixation [PDF]

, 2010
Mesh fixation during laparoscopic ventral hernia repair can be performed using transfascial sutures or metal tacks. The aim of the present study is to compare mesh shrinkage and pain between two different techniques of mesh fixation in a prospective ...
Kurmann, Anita, Candinas, Daniel, Anita Kurmann, Guido Beldi, Beldi, Guido, Markus Wagner, Bruegger, Lukas E, Wagner, Markus, Lukas E. Bruegger, Daniel Candinas   +9 more
core   +2 more sources

First 20 Years of Orbitrap Mass Spectrometry as the Mainstream Analytical Technique

Mass Spectrometry Reviews, EarlyView.
ABSTRACT This review traces the first 20 years of Orbitrap mass spectrometry as a mainstream high‑resolution and accurate‑mass (HR/AM) technology. It outlines the historical development of the Orbitrap analyzer, the evolution of major instrument families, and the key technological innovations that enabled its widespread adoption. Particular emphasis is
Alexander Makarov
wiley   +1 more source

Disease‐Duration–Specific Percentiles for Prospective Subtyping of Parkinson's Disease: A PPMI‐Based Study

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Parkinson's disease (PD) is clinically heterogeneous, with variable progression rates that complicate clinical trial design. The data‐driven diffuse malignant (DM), intermediate (IM), and mild‐motor predominant (MMP) subtyping model has prognostic value but lacks disease duration–specific thresholds for prospective use in disease ...
Ahmed Negida, Nitai Mukhopadhyay, Brian D. Berman, Seyed‐Mohammad Fereshtehnejad, Matthew J. Barrett   +4 more
wiley   +1 more source

Nutritional Treatment After Discharge of Older Patients at Nutritional Risk: A Study Protocol for a Feasibility Study

Medicine Advances, EarlyView.
Older patients at nutritional risk experience a nutritional gap at hospital discharge, and effective cross‐sector nutritional care models remain lacking despite existing evidence. This study's results may help inform the development of a model for large‐scale implementation.
Martine Kjærsgaard Nielsen, Tina Munk, Anne Marie Beck, Jacob Rosenberg, Jesper Ryg   +4 more
wiley   +1 more source

Multicentre randomised controlled trial of nasal diamorphine for analgesia in children and teenagers with clinical fractures. [PDF]

, 2001
OBJECTIVE: To compare the effectiveness of nasal diamorphine spray with intramuscular morphine for analgesia in children and teenagers with acute pain due to a clinical fracture, and to describe the safety profile of the spray.
Latter, VS, Nasal Diamorphine Trial Group, Reeves, BC, Kendall, JM   +3 more
core   +1 more source

Non‐Invasive Triage of Bladder Outlet Obstruction and Detrusor Underactivity in Men With Lower Urinary Tract Symptoms: A Narrative Review and Conceptual Framework for Depth‐Aware Multimodal Transcutaneous Testing

Neurourology and Urodynamics, EarlyView.
ABSTRACT Introduction Differentiating bladder outlet obstruction (BOO) from detrusor underactivity (DU) remains a major unmet need in the management of lower urinary tract symptoms in men. Although pressure–flow urodynamics provide a definitive physiological classification, their invasiveness limits their widespread use.
Sehwan Kim, Bryan K. Kim, John T. Stoffel, Aram Kim   +3 more
wiley   +1 more source