Results 71 to 80 of about 7,099,508 (221)

Supplemental_File – Supplemental material for Using predictive analytics to improve pragmatic trial design

, 2020
Supplemental material, Supplemental_File for Using predictive analytics to improve pragmatic trial design by Susan M Shortreed and Gregory E Simon in Clinical ...
Susan M Shortreed (8560260), Gregory E Simon (8560263)   +1 more
core   +1 more source

Effects of Interprofessional Collaborative Practice in Older Adults’ Hip Fractures Care: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Research in Nursing &Health, EarlyView.
ABSTRACT This study aimed to evaluate the effectiveness of interprofessional collaborative practice interventions in improving activities of daily living, quality of life, length of stay, and in reducing mortality among older adults with hip fractures. Systematic review and meta‐analysis of randomized controlled trials.
Santo Imanuel Tonapa, I‐Chin Huang, Bih‐O Lee, Wendy Chaboyer   +3 more
wiley   +1 more source

Observations from the IMPROVE trial concerning the clinical care of patients with ruptured abdominal aortic aneurysm. [PDF]

, 2013
BACKGROUND: Single-centre series of the management of patients with ruptured abdominal aortic aneurysm (AAA) are usually too small to identify clinical factors that could improve patient outcomes.
Hinchliffe, RJ, Thompson, MM, Bell, R, Greenhalgh, R. M., Ashleigh, R., Grieve, RJ, Ulug, P., Heatley, F., Powell, JT, Sweeting, M. J., Ashleigh, R, Heatley, F, Thompson, S. G., Powell, J. T., Greenhalgh, RM, Gomes, M, Ulug, P, Sweeting, MJ, Gomes, M., ?, ?, Thompson, SG, Hinchliffe, R. J., IMPROVE trial investigators, Thompson, M. M., Bell, Rachel, Grieve, R. J.   +25 more
core   +1 more source

Molecular, spatial, and AI‐enabled technologies for predicting neoadjuvant therapy response in locally advanced rectal cancer

The Journal of Pathology, EarlyView.
Abstract Pretreatment prediction of neoadjuvant response remains an unresolved challenge in locally advanced rectal cancer, where management is moving towards risk‐adapted and response‐oriented treatment strategies. Prediction remains difficult because response reflects interacting tumour‐intrinsic, immune, stromal, and spatial processes that are ...
Gina F Boot, Cibele Masotti, Claudia Corrò, Cédric Schraepen, Hannah L Williams, Thomas A Wright, Fiza Ishaqwala, Colin W Steele, Gertjan Rasschaert, Maxime W Lafarge, Enric Domingo, Inti Zlobec, Rodrigo Oliva Perez, Campbell SD Roxburgh, Timothy S Maughan, Sabine Tejpar, Thibaud Koessler, Viktor H Koelzer   +17 more
wiley   +1 more source

The added value of ordinal analysis in clinical trials: an example in traumatic brain injury. [PDF]

, 2011
INTRODUCTION: In clinical trials, ordinal outcome measures are often dichotomized into two categories. In traumatic brain injury (TBI) the 5-point Glasgow outcome scale (GOS) is collapsed into unfavourable versus favourable outcome.
Perel, P, Steyerberg, Ewout W, IMPACT (International Mission on Prognosis and Clinical Trial De, Edwards, P. (Phil), Steyerberg, Ewout, Ewout W Steyerberg, Phil Edwards, Perel, P. (Pablo), Lingsma, Hester F., Murray, G.D. (Gordon), Steyerberg, Ewout W., Roozenbeek, Bob, Lingsma, Hester F, Gordon D Murray, Andrew IR Maas, Edwards, P, Maas, AIR (Arne), Roberts, I. (Ian), CRASH (Corticosteroid Randomisation After Significant Head Injur, Roberts, Ian, Perel, Pablo, Murray, Gordon D, Maas, A.I.R. (Andrew), ?, ?, Ian Roberts, Maas, Andrew Ir, null null, Edwards, Phil, Steyerberg, E.W. (Ewout), Hester F Lingsma, Murray, Gordon D., Pablo Perel, Roozenbeek, B. (Bob), Murray, GD, Bob Roozenbeek, Maas, Andrew I.R., Lingsma, Hester, Roberts, I   +37 more
core   +1 more source

Diagnosis of Portal Hypertension: Advancing Towards Non‐Invasive Solutions

Portal Hypertension &Cirrhosis, EarlyView.
This review systematically summarizes a full spectrum of non‐invasive diagnostic approaches for portal hypertension (PH), including imaging modalities, elastography, serum biomarkers, composite scoring systems and endoscopic ultrasound‐guided portal pressure gradient (EUS‐PPG), and analyzes their performance across different liver disease etiologies ...
Lijia Yin, Huikuan Chu, Ling Yang
wiley   +1 more source

UK Alcohol Treatment trial: client-treatment matching effects [PDF]

, 2008
Aim To test a priori hypotheses concerning client–treatment matching in the treatment of alcohol problems and to evaluate the more general hypothesis that client–treatment matching adds to the overall effectiveness of treatment. Design Pragmatic,
Raistrick, Duncan, Copello, Alex, McBride, Andrew, Carlyle, Kate, UKATT Res Team, Parkes, Sue, Morton, Veronica, Barrett, Clive, Tober, Gillian, John, Bev, Kenyon, Rob, Kerr, Cicely, Godfrey, Christine, Slegg, Gary P., Smith, Melanie, Chalk, Pauline, UKATT Research Team, Alwyn, Tina, Fleming, Annette, Russell, Ian, Orford, Jim, Hodgson, Ray, Emlyn-Jones, Rhoda, Williams, Paul, Crome, Illana, Kahn, Ash, Farrin, Amanda, Gillam, Racheal, Handforth, Linda, Heather, Nick, Black, Rachel, Coulton, Simon, Parrott, Steve, Champney-Smith, Jeff, Summers, Zelda   +34 more
core   +1 more source

Clinical predictors of response to methotrexate in patients with rheumatoid arthritis: A systematic review

Rheumatology &Autoimmunity, EarlyView.
This review integrates clinical, immunological, genetic, and multi‐omic evidence, highlighting dynamic inflammatory and adenosine‐pathway biomarkers and reinforcing treat‐to‐target principles as the most actionable framework for personalized methotrexate therapy.
Joana Ramos Rodrigues, Helena Margarida de Miranda Lemos Romão Donato, Soraia Raquel Loureiro Azevedo, Luís Miguel da Silva Pires, Luís Pedro Bolotinha de Sousa Inês, Manuel Augusto Nunes Vicente Passos Morgado, Ana Filipa de Sousa Pestana Mourão   +6 more
wiley   +1 more source

Determinants of Community Resilience: A Multi‐Level Synthesis of Empirical and Conceptual Evidence

Sustainable Development, EarlyView.
ABSTRACT Community resilience research remains fragmented across disciplines, with limited integration of empirical evidence and conceptual scholarship. This study addresses this gap through a directed content analysis of 48 empirical case studies and 39 conceptual and review publications from diverse geographical and hazard contexts.
Anamol Neupane, Seweryn Zielinski, Iroda Mukhammadieva   +2 more
wiley   +1 more source

Visionary, engineer, and experimenter: Three forms of entrepreneurship in the quest for product–market fit

Strategic Entrepreneurship Journal, EarlyView.
Abstract Research summary Entrepreneurship unfolds under uncertainty, which complicates entrepreneurs' efforts to align idea, action, and environment to reach product–market fit. To illuminate how entrepreneurs perform such alignment, we complement the theory‐based view and its focus on cognitive uncertainty with a discussion of behavioral uncertainty.
Thomas Zellweger, Djordje Djokovic
wiley   +1 more source