Stochasticity in the symmetric division of plant cells:when the exceptions are the rule [PDF]
Berthold +23 more
core +4 more sources
Abstract Objective Dravet syndrome (DS) is the prototypic developmental and epileptic encephalopathy, characterized by drug‐resistant seizures, developmental slowing, and many other morbidities. Detailed characterization of behavioral phenotypes and social–emotional skill development are limited.
Ingrid E. Scheffer +26 more
wiley +1 more source
Negative spillover due to constraints on care delivery: a potential source of bias in pragmatic clinical trials. [PDF]
Mann S.
europepmc +1 more source
Defining the end point of status epilepticus: A scoping review and framework for standardization
Abstract Status epilepticus (SE) is a life‐threatening neurological emergency with consensus‐driven definitions for onset but no standardized criteria for its end point. This gap creates uncertainty in research and clinical practice. We conducted a scoping review to evaluate how end points have been defined in SE research and to identify key areas of ...
Fawad A. Khan +6 more
wiley +1 more source
Bridging research and practice: enhancing regulatory decisions with pragmatic clinical trials in oncology. [PDF]
Stewart MD +6 more
europepmc +1 more source
Creativity and its link to epilepsy
Abstract Creative thinking represents one of our highest‐order cognitive processes, involving multiple cortical structures and an intricate interplay between several cortical and subcortical networks. It results in novel ideas that translate to useful products or concepts. The evolutionary purpose of creativity is therefore apparent, as it advances our
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
Individualized clinical decisions within standard-of-care pragmatic clinical trials: Implications for consent. [PDF]
Astrachan IM, Flory J, Kim SY.
europepmc +1 more source
Out of the lab, into real life: Evaluating at‐home EEG self‐monitoring
Abstract Seizure forecasting models require long‐term, high‐quality data collected in real‐life settings using noninvasive or minimally invasive devices, yet, the lack of such systems remains a major barrier to their clinical translation. Here, we aimed to evaluate the signal quality of self‐applied at‐home EEG monitoring using a wearable system in ...
Louis Cousyn +7 more
wiley +1 more source
Engaging clinical partners in pragmatic clinical trials: lessons learned from the pain management collaboratory. [PDF]
Bastian LA +5 more
europepmc +1 more source

