Negative spillover due to constraints on care delivery: a potential source of bias in pragmatic clinical trials. [PDF]
Mann S.
europepmc +1 more source
Tackling cancer stemness with nanotechnology in the era of precision medicine
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo +9 more
wiley +1 more source
Bridging research and practice: enhancing regulatory decisions with pragmatic clinical trials in oncology. [PDF]
Stewart MD +6 more
europepmc +1 more source
ABSTRACT Environmental management accounting (EMA) is increasingly recognised as essential for carbon governance, accountability and net zero transitions, yet research has overlooked how sustainability is negotiated within mission‐driven but commercially exposed service organisations such as private hospitals in developing economies, a sector often ...
M. M. Swalih, Ronita Ram, Edward Tew
wiley +1 more source
Individualized clinical decisions within standard-of-care pragmatic clinical trials: Implications for consent. [PDF]
Astrachan IM, Flory J, Kim SY.
europepmc +1 more source
The Age of Questions: Truth Regimes and Subjectivity in the Era of Large Language Models
ABSTRACT This essay explores how digital technologies shape subjectivity's infra‐political constitution, focusing on large language models (LLMs) like ChatGPT or Gemini within what philosophers, inspired by Michel Foucault, term the “digital truth regime.” After defining this regime, the essay identifies five key traits of LLMs: presentism in truth ...
Charles Corval
wiley +1 more source
Engaging clinical partners in pragmatic clinical trials: lessons learned from the pain management collaboratory. [PDF]
Bastian LA +5 more
europepmc +1 more source
ABSTRACT Personalized learning approaches adapted to individual metacognitive characteristics have demonstrated promise in Anatomy education. However, whether such benefits are uniform across learner profiles or vary systematically remains an open question with implications for individualized instructional approaches.
Mónica Stambuk‐Castellano +6 more
wiley +1 more source
Monitoring and reporting adverse events in pragmatic clinical trials testing nonpharmacological pain management interventions. [PDF]
Burns A +10 more
europepmc +1 more source
ABSTRACT Background Biodegradable‐polymer (BP) drug‐eluting stents (DES) were developed to mitigate potential late adverse events related to persistent durable polymers in durable‐polymer (DP) DES; however, contemporary long‐term real‐world comparative data remain limited. Aims We aimed to compare the 5‐year clinical outcomes of contemporary BP‐DES and
Yangyoun Lee +6 more
wiley +1 more source

