Results 111 to 120 of about 24,469 (191)

After the green light: Evaluating drugs in Phase IV studies.

Indian J Pharmacol
Meher BR, Mishra A.
europepmc   +1 more source

A methodological review of pragmatic designs in acute stroke trials. [PDF]

Int J Stroke
Okikiolu AP, Ray S, Chakravarty K, Arimoro O, Martens R, Singh N, Ganesh A, Almekhlafi M, Hill MD, Menon BK, Sajobi TT.   +10 more
europepmc   +1 more source

Creativity and its link to epilepsy

Epilepsia Open, EarlyView.
Abstract Creative thinking represents one of our highest‐order cognitive processes, involving multiple cortical structures and an intricate interplay between several cortical and subcortical networks. It results in novel ideas that translate to useful products or concepts. The evolutionary purpose of creativity is therefore apparent, as it advances our
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Non-inferiority of saline versus corticosteroid injections for trapeziometacarpal osteoarthritis: a protocol for a pilot and feasibility randomised controlled trial. [PDF]

BMJ Open
Gevers-Montoro C, Freire V, Harris PG, Ruel M, Luong DH, Bureau NJ, Bois MC, Aribert M, Efanov JI, Filali-Mouhim A, Piché M, Hamasaki T.   +11 more
europepmc   +1 more source

Perampanel as add‐on in high‐grade glioma–related epilepsy: Seizure control and QoL in a prospective, multicenter, real‐world 6‐month follow‐up study

Epilepsia Open, EarlyView.
Abstract Objective High‐grade astrocytomas, including glioblastomas, are aggressive brain tumors with poor prognosis and a 5‐year survival below 7%. Seizures affect up to 75% of glioma patients, especially in low‐grade tumors but also in high‐grade cases.
Matteo Impellizzeri, Paolo Paone, Giada Pauletto, Annacarmen Nilo, Simone Beretta, Andrea Salmaggi, Stefano Consoli, Stefano Quadri   +7 more
wiley   +1 more source

Aligning Research With Practice: Nursing Home Providers' Priorities for Long-Term Care Research. [PDF]

J Am Geriatr Soc
Chen BG, Recker A, Baier RR, Reddy A, Gifford DR, Kissam SM.   +5 more
europepmc   +1 more source

Progressive myoclonus epilepsy in Down syndrome with Alzheimer's disease: An 11‐year longitudinal study and proposed diagnostic red flags

Epilepsia Open, EarlyView.
Abstract Objective Individuals with Down syndrome (DS) face an ultra‐high risk of Alzheimer's disease (AD). Within this continuum, Progressive Myoclonus Epilepsy (PME) has emerged as a marker of advanced neurodegeneration. Building on our 2014 characterization of this syndrome, we aimed to define its long‐term natural history and pathological substrate.
Giuseppe d'Orsi, Ezio Calò, Maria Teresa Di Claudio, Carmela Pia Ferro, Umberto Costantino, Elio Perrone, Raffaela Rita Latino   +6 more
wiley   +1 more source

Antibiotic therapy in viral airway infections (ATHENIAN): study protocol for an open labeled randomized controlled pragmatic trial to evaluate the efficacy and safety of discontinuing antibiotic therapy in adult patients infected with respiratory viruses. [PDF]

Trials
Hovind MJ, Berdal JE, Benth JŠ, Dalgard O, Lyngbakken MN.   +4 more
europepmc   +1 more source

Beyond seizures: A multidimensional approach to non‐seizure issues in Lennox–Gastaut syndrome. Insights from Italian experts

Epilepsia Open, EarlyView.
Abstract Non‐seizure issues (NSIs), including cognition, behavior/psychiatric symptoms, adaptive and social functioning, sleep, autonomic, and motor impairments, often shape day‐to‐day outcomes in Lennox–Gastaut syndrome (LGS) more than seizures, yet clinicians lack LGS‐specific, feasible assessment pathways.
Giancarlo Di Gennaro, Domenica Immacolata Battaglia, Paolo Bonanni, Gian Marco Duma, Antonietta Coppola, Edoardo Ferlazzo, Dario Pruna, Carlo Di Bonaventura   +7 more
wiley   +1 more source

A methodological protocol for multimodal profiling of conversational abilities in mandarin-speaking children with and without developmental language disorder. [PDF]

Front Psychol
Wang C, Xu J, Yao M, Wang J, Hong Q, Zhao H, Chi X.   +6 more
europepmc   +1 more source