Results 151 to 160 of about 44,864,774 (235)

A Little Support Goes a Long Way: A Mixed‐Methods Pilot Study of Supported Digital CBTe for Recurrent Binge Eating

International Journal of Eating Disorders, EarlyView.
ABSTRACT Background Eating disorders characterized by recurrent binge eating are prevalent, impairing, and undertreated. Digital programme‐led interventions may increase access to recommended treatments, but completion rates are variable. Adding brief human support to digital programmes may improve completion and outcomes.
Rebecca Murphy, Emma L. Osborne, Charandeep K. Khera   +2 more
wiley   +1 more source

Using the readiness assessment for pragmatic trials (RAPT) model to structure partner engagement and strengthen pragmatic research readiness. [PDF]

J Clin Transl Sci
Baier RR, Serina PT, Reddy A, Stanislawski A, Hunkins N, McCreedy E.   +5 more
europepmc   +1 more source

The difficult discussion on the deactivation of implantable cardioverter devices at the end of life: a systematic review

ESC Heart Failure, Volume 12, Issue 2, Page 733-760, April 2025.
Abstract Implantable cardioverter defibrillators (ICDs) reliably prevent death due to life‐threatening arrhythmias; this may become less relevant in people with more severe heart failure who are reaching the end of life (EOL). This review aimed to explore the ICD deactivation process and identify ethical issues, especially around the initiation of ...
Siobhan C. Murray, Claire McNamara, Anna V. Chatzi   +2 more
wiley   +1 more source

After the green light: Evaluating drugs in Phase IV studies.

Indian J Pharmacol
Meher BR, Mishra A.
europepmc   +1 more source

Aligning Research With Practice: Nursing Home Providers' Priorities for Long-Term Care Research. [PDF]

J Am Geriatr Soc
Chen BG, Recker A, Baier RR, Reddy A, Gifford DR, Kissam SM.   +5 more
europepmc   +1 more source

Mortality risk stratification for Takotsubo syndrome: Evaluating CRP measurement alongside the InterTAK prognostic score

ESC Heart Failure, Volume 12, Issue 2, Page 1427-1436, April 2025.
Abstract Background and objectives Initially described as a benign acute cardiomyopathy, Takotsubo syndrome has been linked to elevated mortality rates. Emerging evidence suggests that unresolved myocardial inflammation may contribute to this adverse prognosis.
Loïc Faucher, Kensuke Matsushita, Shinnosuke Kikuchi, Taraneh Tatarcheh, Benjamin Marchandot, Amandine Granier, Said Amissi, Antonin Trimaille, Laurence Jesel, Patrick Ohlmann, Kiyoshi Hibi, Valérie Schini‐Kerth, Olivier Morel   +12 more
wiley   +1 more source

A Framework to Decipher and Report Implementation Strategies and Pragmatic Attributes of Trial Design Domains From Pre-Implementation Studies Identified From a Systematic Review: A Methodological Study. [PDF]

J Eval Clin Pract
Ajja R, Suresh V, Wang S, Elashker A, Ordorica C, Bosworth HB, Moore JB, Rudd BN, Pokharel Y.   +8 more
europepmc   +1 more source

Diagnostic Lag in Precision Medicine

Clinical Pharmacology &Therapeutics, EarlyView.
Petr Heneberg
wiley   +1 more source

The effectiveness of adding on or switching antiseizure medications after the first fails to control focal epilepsy: A systematic review of randomized controlled trials

Epileptic Disorders, EarlyView.
Abstract Focal epilepsy constitutes 60–70% of epilepsy, and up to half of patients do not achieve seizure freedom with their first antiseizure medication (ASM). When the first ASM fails, evidence guiding whether to switch or add‐on another ASM and which ASMs to use is limited. This review synthesized evidence from randomized controlled trials (RCTs) on
Isaac J. Egesa, Gashirai Mbizvo, Michelle Maden, Thomas Spain, Richard Emsley, Laura J. Bonnett, Anthony G. Marson, Catrin Tudur Smith   +7 more
wiley   +1 more source

Non-inferiority of saline versus corticosteroid injections for trapeziometacarpal osteoarthritis: a protocol for a pilot and feasibility randomised controlled trial. [PDF]

BMJ Open
Gevers-Montoro C, Freire V, Harris PG, Ruel M, Luong DH, Bureau NJ, Bois MC, Aribert M, Efanov JI, Filali-Mouhim A, Piché M, Hamasaki T.   +11 more
europepmc   +1 more source