Results 191 to 200 of about 79,378 (235)

High posterior tibial slope increases graft failure risk but does not impair functional outcomes after primary ACL reconstruction

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Posterior tibial slope (PTS) has been implicated in anterior cruciate ligament (ACL) graft failure, but its relationship to objective stability and patient‐reported outcomes (PROs) after primary ACL reconstruction (ACLR) remains unclear. The study evaluated whether higher PTS is associated with laximetry, graft survival, and PROs after
Paul Souvik   +5 more
wiley   +1 more source

Recurrent Respiratory Papillomatosis Foundation Position Statement on the Management of Adults With RRP

open access: yesThe Laryngoscope, EarlyView.
ABSTRACT Objective With regulatory approval of HPV‐specific immunotherapy for recurrent respiratory papillomatosis (RRP) and growing experience with systemic bevacizumab, a management algorithm incorporating these medical treatments is warranted. Data Sources and Methods RRP Foundation (RRPF) Key Opinion Leaders offer a proposed management algorithm ...
Simon R. Best   +17 more
wiley   +1 more source

Traditional Chinese Medicine as an Integrative Adjunct in Oncology Perioperative Practice: Analgesia, Immune Modulation, and Translational Challenges

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT Traditional Chinese medicine (TCM), including herbal analgesic adjuvants and acupuncture‐based interventions, has gained increasing attention as an integrative strategy for perioperative pain management in oncology. Bioactive phytochemicals—such as terpenoids, flavonoids, alkaloids, and polyphenols—exert multimodal pharmacological effects ...
Yuqin Tang   +5 more
wiley   +1 more source

Ethical considerations in implementation research: a scoping review of key principles, unintended consequences, and emerging ethical guidance. [PDF]

open access: yesImplement Sci Commun
Tetteh EK   +7 more
europepmc   +1 more source

Psychiatric Comorbidity, Tic Severity and Quality of Life in Adults with Tourette's Syndrome

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Psychiatric comorbidities are common in adults with Tourette's Syndrome (TS), and appear to influence both tic severity and quality of life (QOL). Objective To assess the association between psychiatric comorbidities, tic severity and QOL in TS.
Andreas Hartmann   +9 more
wiley   +1 more source

Smart Integration of Structural Biology and Medicinal Chemistry to Unlock Target‐Driven Drug Discovery

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT To enhance drug discovery efforts, medicinal chemists should evaluate, filter, and utilize relevant structural information about target proteins. Acquiring and interpreting protein structures is crucial for elucidating ligand‐receptor interactions and addressing ADME‐related considerations, making it an essential aspect of medicinal chemistry.
Matteo Rossi Sebastiano   +4 more
wiley   +1 more source

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