Results 151 to 160 of about 3,627,712 (198)

Case report: Treatment of severe phorate poisoning. [PDF]

Front Toxicol
Kunlun W, Jun Y, Shiming X, Jie S, Mingqiang G, Yuxia Z, Weichun M.   +6 more
europepmc   +1 more source

Spatiotemporal perturbations of the plasminogen activation system in a rat model of acute organophosphate intoxication. [PDF]

Acta Neuropathol Commun
Blackmon TJ, MacMahon JA, Bernardino PN, Hogans RE, Cheng MY, Vu J, Lee RD, Saito NH, Grodzki AC, Bruun DA, Wulff H, Woolard KD, Brooks-Kayal A, Harvey DJ, Gorin FA, Lein PJ.   +15 more
europepmc   +1 more source

Trends in emergency department visits for acute intoxication: a 3-year retrospective study in Hangzhou, East China. [PDF]

Front Public Health
Li C, Zhang H, Yang B.
europepmc   +1 more source

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Montmorillonite Functionalized with Pralidoxime As a Material for Chemical Protection against Organophosphorous Compounds

ACS Applied Materials & Interfaces, 2011
Montmorillonite K-10 functionalized with α-nucleophilic 2-pralidoxime (PAM) and its zwitterionic oximate form (PAMNa) is introduced as a versatile material for chemical protection against organophosphorous (OP) compounds such as pesticides and chemical warfare agents (CWA).
Lev, Bromberg, Christine M, Straut, Andrea, Centrone, Eugene, Wilusz, T Alan, Hatton   +4 more
openaire   +3 more sources

Method validation for simultaneous determination of atropine, pralidoxime and 12 organophosphorus compounds in blood samples by means of high-performance liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS)

Journal of Chromatography B, 2018
Abstract Organophosphorus (OP) compounds stand out as one of the most extensively used pesticides' class worldwide, being associated with a high prevalence of voluntary and accidental poisoning in humans. These compounds promote inhibition of the acetylcholinesterase (AChE) leading to the accumulation of acetylcholine in the central and peripheral ...
Graziany L M, Marques, Alciene A, Siqueira, Vítor S, Minassa, Mariana D, Peres, Fabrício S, Pelição, Karla N, Sampaio   +5 more
openaire   +3 more sources

Protective Effect of Pralidoxime on Muscle Fiber Necrosis Induced by Organophosphate Compounds

Journal of Toxicology: Clinical Toxicology, 1998
To determine the protective effect of pralidoxime on muscle fiber necrosis induced by organophosphate acute intoxication in rats.Adult male Wistar rats were given oral organophosphate compounds dissolved in glycerol formal: dichlorvos, isofenphos, metamidophos, and diazinon.
M J, Cavaliere, F R, Puga, E E, Calore, N M, Calore, J R, Pelegrino, A R, da Rosa, R, Weg   +6 more
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Catalytic reduction of pralidoxime in pharmaceuticals by macrocyclic Ni(II) compounds derived from orthophthalaldehyde

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2008
Efficient catalytic method for the reduction of pralidoxime to its amine derivative by macrocyclic Ni(II) compounds has been developed. Ten macrocyclic Schiff base Ni(II) compounds were synthesized via non-template synthesis by treating the corresponding macrocycles with nickel chloride in 1:1 ratio.
P Muralidhar, Reddy, Adapa V S S, Prasad, Rondla, Rohini, Vadde, Ravinder   +3 more
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Reactivating potency of obidoxime, pralidoxime, HI 6 and HLö 7 in human erythrocyte acetylcholinesterase inhibited by highly toxic organophosphorus compounds

Archives of Toxicology, 1998
The treatment of poisoning by highly toxic organophosphorus compounds (nerve agents) is unsatisfactory. Until now, the efficacy of new potential antidotes has primarily been evaluated in animals. However, the extrapolation of these results to humans is hampered by species differences.
F, Worek, R, Widmann, O, Knopff, L, Szinicz   +3 more
openaire   +3 more sources