Results 81 to 90 of about 149,648 (111)
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Asian Journal of Research in Chemistry, 2016
Three simple and sensitive extractive spectrophotometric methods have been described for the assay of ondansetron hydrochloride either in pure form or in pharmaceutical formulations. The developed methods involve formation of coloured chloroform extractable ion-pair complexes of the drug with bromothymol blue (BTB), bromophenol blue (BPB) and ...
M. Chennaiah
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Three simple and sensitive extractive spectrophotometric methods have been described for the assay of ondansetron hydrochloride either in pure form or in pharmaceutical formulations. The developed methods involve formation of coloured chloroform extractable ion-pair complexes of the drug with bromothymol blue (BTB), bromophenol blue (BPB) and ...
M. Chennaiah
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Journal of Liquid Chromatography & Related Technologies, 2012
A simple, sensitive, and reproducible gradient reverse-phase ultra-performance liquid chromatographic (UPLC) method was developed for the quantitative determination of Prasugrel and all possible process-related impurities (positional isomers, degradants and byproducts) at the level of 0.5–2.0 µg mL−1.
V. Malati +3 more
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A simple, sensitive, and reproducible gradient reverse-phase ultra-performance liquid chromatographic (UPLC) method was developed for the quantitative determination of Prasugrel and all possible process-related impurities (positional isomers, degradants and byproducts) at the level of 0.5–2.0 µg mL−1.
V. Malati +3 more
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International Journal of Drug Delivery Technology
Prasugrel hydrochloride (Prasugrel HCl), a potent thienopyridine-class antiplatelet agent, is classified as a Biopharmaceutics Classification System (BCS) Class II drug, characterized by low aqueous solubility and high permeability, which limits its oral
Suryawanshi A.N., Ratnaparkhi M.P.
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Prasugrel hydrochloride (Prasugrel HCl), a potent thienopyridine-class antiplatelet agent, is classified as a Biopharmaceutics Classification System (BCS) Class II drug, characterized by low aqueous solubility and high permeability, which limits its oral
Suryawanshi A.N., Ratnaparkhi M.P.
semanticscholar +1 more source
Prasugrel hydrochloride, dronedarone, and saxagliptin hydrochloride
Journal of the American Pharmacists Association, 2009Antiplatelet agent Acute coronary syndrome (ACS), which includes unstable angina and myocardial infarction (MI), affects approximately 1.5 million Americans each year. Many of these individuals are candidates for percutaneous coronary intervention (PCI; angioplasty), a procedure in which a balloon device is used to open coronary arteries that are ...
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Arzneimittelforschung, 2011
Prasugrel (CAS 150322-43-3), an inhibitor of platelet activation and aggregation, is indicated to reduce the rate of thrombotic cardiovascular events in patients with acute coronary syndrome. If a proton pump inhibitor is co-administered with prasugrel, a pH dependent salt-to-base conversion rate of prasugrel could become clinically meaningful.
Dan, Seiler +2 more
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Prasugrel (CAS 150322-43-3), an inhibitor of platelet activation and aggregation, is indicated to reduce the rate of thrombotic cardiovascular events in patients with acute coronary syndrome. If a proton pump inhibitor is co-administered with prasugrel, a pH dependent salt-to-base conversion rate of prasugrel could become clinically meaningful.
Dan, Seiler +2 more
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Blood, 2005
Abstract The thienopyridine antiplatelet prodrug clopidogrel bisulfate (C) is widely used for atherothrombotic diseases. However, several reports have described a limitation of C, namely, poor platelet inhibition in many patients following oral dosing.
Yoichi Niitsu +7 more
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Abstract The thienopyridine antiplatelet prodrug clopidogrel bisulfate (C) is widely used for atherothrombotic diseases. However, several reports have described a limitation of C, namely, poor platelet inhibition in many patients following oral dosing.
Yoichi Niitsu +7 more
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Asian Journal of Research in Chemistry
The present work reports rapid, sensitive and specific methods for determination of Prasugrel and its impurities by gas chromatography with mass spectrometry and high-performance liquid chromatography. The proposed method presented excellent intraday precision (% RSD < 1), and accuracy 99.23 to 100.40% and 99.48 to 100.81% for Prasugrel and 2-bromo ...
Manohar Reddy Epuru +3 more
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The present work reports rapid, sensitive and specific methods for determination of Prasugrel and its impurities by gas chromatography with mass spectrometry and high-performance liquid chromatography. The proposed method presented excellent intraday precision (% RSD < 1), and accuracy 99.23 to 100.40% and 99.48 to 100.81% for Prasugrel and 2-bromo ...
Manohar Reddy Epuru +3 more
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ChemInform Abstract: An Improvement to the Preparation of Prasugrel Hydrochloride (I).
ChemInform, 2013Wenhua Ou +4 more
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