Results 91 to 100 of about 37,525 (284)

Metabolic profiling of praziquantel enantiomers [PDF]

Biochemical Pharmacology, 2014
Praziquantel (PZQ), prescribed as a racemic mixture, is the most readily available drug to treat schistosomiasis. In the present study, ultra-performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight mass spectrometry (UPLC-ESI-QTOFMS) based metabolomics was employed to decipher the metabolic pathways and ...
Jeffrey R. Idle, Changyan Hu, Dequn Sun, Zhong-Ze Fang, Kun Zhou, Haina Wang, Yang Zheng, Kristopher W. Krausz, Frank J. Gonzalez   +8 more
openaire   +3 more sources

Update on the Seroepidemiology of Human Cystic Echinococcosis and Associated Risk Factors in Iran: A Systematic Review and Meta‐Analysis

Health Science Reports, Volume 8, Issue 4, April 2025.
ABSTRACT Background and Aims Cystic echinococcosis (CE) poses a significant public health challenge in developing countries, including Iran. This systematic review and meta‐analysis aim to enhance our understanding of CE prevalence by providing an updated assessment of the general prevalence of human CE in Iran through a comprehensive review of the ...
Nashmin Mohemmi, Mohammad Taghi Khodayari, Seyed Ahmad Karamati, Mohammad Reza Shiee, Hossein Effatpanah, Afshin Davari, Ali Reza Ghorbani, Arezoo Bozorgomid   +7 more
wiley   +1 more source

Efficacy of praziquantel treatment regimens in pre-school and school aged children infected with schistosomiasis in sub-Saharan Africa: a systematic review

Infectious Diseases of Poverty, 2018
BackgroundSchistosomiasis is a serious public health burden in sub-Saharan Africa. Praziquantel is the only drug recommended by the World Health Organization to treat both urogenital and intestinal schistosomiasis.
Muhubiri Kabuyaya, M. Chimbari, S. Mukaratirwa   +2 more
semanticscholar   +1 more source

Efficacy of imidacloprid 10%/moxidectin 1% spot-on formulation (Advocate®) in the prevention and treatment of feline aelurostrongylosis [PDF]

, 2020
Background: In three randomized, controlled laboratory efficacy studies, the efficacy in the prevention of patent infections of a topical combination of imidacloprid 10%/moxidectin 1% (Advocate® spot-on formulation for cats, Bayer Animal Health GmbH ...
Blazejak, Katrin, Deuster, Katrin, Heuer, Lea, McKay-Demeler, Janina, Petry, Gabriele, Pollmeier, Matthias, Samson-Himmelstjerna, Georg von, Schaper, Roland, Schmidt, Holger, Strube, Christina   +9 more
core   +1 more source

Persistent Abdominal Pain and Diarrhea After Appendectomy—Crohn's Disease Versus Intestinal Tuberculosis

JGH Open, Volume 9, Issue 4, April 2025.
ABSTRACT Case Presentation In Western Europe, intestinal tuberculosis is a rare differential diagnosis for Crohn's disease. In this report, we present a case of intestinal tuberculosis in a 59‐year‐old female initially suspected of Crohn's disease with persistent abdominal pain and diarrhea after appendectomy.
Jonas Wizenty, Martin Maibier, Michael Sigal   +2 more
wiley   +1 more source

Antischistosomal and anti-inflammatory activity of garlic and allicin compared with that of praziquantel in vivo

BMC Complementary and Alternative Medicine, 2018
BackgroundSchistosomiasis is an acute and chronic zoonotic parasitic disease caused by trematode worms. The host inflammatory response to schistosome eggs leads to perioval granulomata formation, mainly in the liver and intestine. This study investigated
D. Metwally, E. Al-Olayan, M. Alanazi, Sanaa B. Alzahrany, A. Semlali   +4 more
semanticscholar   +1 more source

Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on immune responses to schistosome antigens among the offspring: results of a randomised, placebo-controlled trial. [PDF]

, 2011
BACKGROUND: Offspring of women with schistosomiasis may exhibit immune responsiveness to schistosomes due to in utero sensitisation or trans-placental transfer of antibodies.
Cose, Stephen, Dunne, David W, Elliott, Alison M, Jones, Frances M, Kihembo, Macklyn, Mawa, Patrice A, Tweyongyere, Robert, Vennervald, Birgitte J, Webb, Emily L   +8 more
core   +5 more sources

Pharmacological and immunological effects of praziquantel against Schistosoma japonicum: a scoping review of experimental studies

Infectious Diseases of Poverty, 2018
BackgroundChemotherapy for schistosomiasis has been around for 100 years. During the past century, great efforts have been made to develop new antischistosomal drugs from antimonials to nonantimonials, and some of these have been used extensively in ...
S. Xiao, Jun Sun, Ming-gang Chen
semanticscholar   +1 more source

Australian guidelines for equine internal parasite management

Australian Veterinary Journal, Volume 103, Issue 4, Page 151-158, April 2025.
Over the past few decades, the emergence of resistance amongst intestinal parasites of horses to all available anthelmintic classes has emphasised the need for a paradigm shift in parasite control approaches within the Australian equine industry. Findings of a recent Australia‐wide research project have provided new insights into intestinal parasites ...
A Beasley, G Abbas, K Hughes, C El‐Hage, C Jacobson, J Bauquier, E Wilkes, P Carrigan, L Cudmore, J Hurley, I Beveridge, M Nielsen, A Jabbar   +12 more
wiley   +1 more source

Identification of training needs in schistosomiasis research to build capacity for schistosomiasis control in Uganda

Tropical Medicine &International Health, Volume 30, Issue 4, Page 314-321, April 2025.
Abstract Background Schistosomiasis is the leading cause of fatal upper gastrointestinal bleeding among adults in East Africa. The prevalence among school‐aged children in villages along the Albert–Nile shoreline in North‐Western Uganda is estimated at 85%.
Damalie Nakanjako, Moses Egesa, Helen Byakwaga, Casim Umba Tolo, Anatol Maranda Byaruhanga, Prudence Beinamaryo, Grace Banturaki, Lydia Nakiyingi, Ponsiano Ocama, Moses R. Kamya, Alison M. Elliott   +10 more
wiley   +1 more source