Results 81 to 90 of about 19,502 (213)

Single‐Cell and Spatial Transcriptomics Unveil Key Regulators Governing Cell Differentiation for Schistosoma japonicum Sexual Development

Advanced Science, Volume 13, Issue 53, 24 September 2026.
Using single‐cell and spatial transcriptomics, we identified key regulators that govern cell differentiation involved in parasite development and egg laying in Schistosoma japonicum. This comprehensive study establishes a foundational resource for understanding schistosome biology, deciphers the regulatory programs underlying cell differentiation and ...
Zhigang Lu, Xiaoxu Wang, Shun Li, Xuxin Li, Pengfei Du, Yameng Zheng, Lu Liu, Yanyan Zhang, Omri Wurtzel, Guofeng Cheng   +9 more
wiley   +1 more source

A Rapid Appraisal of Factors Influencing Praziquantel Treatment Compliance in Two Communities Endemic for Schistosomiasis in Côte d’Ivoire

Tropical Medicine and Infectious Disease, 2018
Over the past decade, a significant reduction in the prevalence of schistosomiasis has been achieved, partially explained by the large-scale administration of praziquantel.
Jean T. Coulibaly, Mamadou Ouattara, Beatrice Barda, Jürg Utzinger, Eliézer K. N’Goran, Jennifer Keiser   +5 more
doaj   +1 more source

Unusual Spinal Epidural and Paraspinal Venous Engorgement Secondary to Hepatosplenic Schistosomiasis: A Rare Cause of Severe Low Back Pain

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Severe low back pain from spinal epidural and paraspinal venous engorgement secondary to hepatosplenic schistosomiasis is rare. MRI revealed dilated epidural veins and neural foraminal narrowing. The patient was managed conservatively with analgesia and carvedilol for portal hypertension and subsequently experienced complete resolution of back
Endalew Dessie Birara, Yonas Damtew Bejiga, Rediet Girmaye, Elias Getahun Bayu, Hosea Manyazewal Anberber, Alefe Aklewok Tadesse, Habtamu Ferede Kidanu, Ragasa Getachew Bayisa, Tamirat Godebo Woyimo   +8 more
wiley   +1 more source

Praziquantel-induced tegumental damage in vitro is diminished in schistosomes derived from praziquantel-resistant infections

, 2001
The aggressive use of praziquantel to combat schistosomiasis in Egpyt raises concern about the possible emergence of resistance. Eggs from Egyptian patients with praziquantel-resistant infections (not cured by 3 doses of praziquantel) have been used to ...
J.L. BENNETT, T.A. DAY, S. BOTROS, M. ISMAIL, S. WILLIAM, A. FARGHALLY   +5 more
core   +1 more source

Treatment of hepatic and pulmonary hydatidosis with albendazole and praziquantel

Helminthologia, 2023
Conservative treatment of human hydatidosis (cystic echinococcosis) with albendazole has improved significantly the prognosis of the disease. But its therapeutic effectiveness is 30 – 70 %. There is some evidence that the effectiveness of albendazole can
Popova G., Vuchev D., Anichina K.
doaj   +1 more source

Determining treatment needs at different spatial scales using geostatistical model-based risk estimates of schistosomiasis [PDF]

, 2012
BACKGROUND: After many years of neglect, schistosomiasis control is going to scale. The strategy of choice is preventive chemotherapy, that is the repeated large-scale administration of praziquantel (a safe and highly efficacious drug) to at-risk ...
Utzinger Jürg, Vounatsou Penelope, Schur, N., Vounatsou, P., Utzinger, J., Schur Nadine, Jürg Utzinger, Penelope Vounatsou, Nadine Schur, Schur N, Utzinger J, Vounatsou P   +11 more
core   +2 more sources

Proliferative Sparganosis Due to Spirometra mansoni in a Dog: A Detailed Diagnostic Picture

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Innumerable small oval cystic structures were identified in the peritoneal cavity of a young dog presenting with abdominal distension and weight gain. A combination of diagnostics confirmed these structures as Spirometra mansoni plerocercoids and established a diagnosis of proliferative sparganosis.
Stephanie Middlemast, Nicholas Lim, Charles G. Gauci, Abdul Jabbar   +3 more
wiley   +1 more source

Praziquantel synthesis [PDF]

, 1999
This paper deals mainly with the synthesis of praziquantel, a powerful anti-helminthic used against schistosomiasis, an endemic disease which infest millions of people around the world.Instituto de Química ...
Novaes, Maria Rita Carvalho Garbi, Araújo, Hugo Clemente de, Souza, João Pedro de   +2 more
core   +1 more source

Effects of Different Living Environments on Intestinal Flora in Patients With Schistosoma Japonicum‐Induced Liver Fibrosis

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Different living environments have a significant impact on the gut microbiota of patients with Schistosoma japonicum. ABSTRACT Schistosomiasis japonica is a parasitic disease leading to liver cirrhosis. China's “fishermen going ashore” policy divides patients with schistosomiasis liver fibrosis into two groups: those near the infected waters and those ...
Xiaofei Fan, Chen Zhou, Pengpeng Zhang, Yingzi Ming   +3 more
wiley   +1 more source

3D Liver Fibrosis Models in Lab: A Novel Modality for Drug Screening

Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
ABSTRACT Liver fibrosis is the common consequence of liver injury caused by a variety of chronic liver disorders. This condition leads to the development of more severe complications, particularly cirrhosis and hepatocellular carcinoma. Despite abundant studies, the fundamental cell and molecular mechanisms of liver fibrosis are still unknown.
Hani Keshavarz Alikhani, Fatemeh Majidi, Mahsa Ghasemzad, Anastasia Shpichka, Anastasia Nestorova, Zahra Hendi, Elham Rismani, Daria Kuznetsova, Peter Timashev, Massoud Vosough, Abbas Piryaei   +10 more
wiley   +1 more source