Results 91 to 100 of about 26,897 (178)

Baiting not-owned dogs against Echinococcus granulosus: innovative tools for integrated control

open access: yesParasitology
Cystic echinococcosis (CE), caused by the larval stage of the cestode Echinococcus granulosus, is one of the most widespread zoonoses in Mediterranean countries. Baiting not-owned dogs with praziquantel (PZQ), due to their key role in the maintaining the
Elena Ciccone   +15 more
doaj   +1 more source

Effect of Praziquantel on Preventing Delayed Infection of Schistosoma japonicum in Buffaloes and Goats

open access: yesMicroorganisms
Schistosomiasis, caused by Schistosoma japonicum, continues to pose a major public health threat in East Asia, with an estimated 71 million people at risk of infection. Domestic animals, especially buffaloes and goats, serve as important reservoir hosts,
Xiang Gui   +11 more
doaj   +1 more source

A new approach to assessing the efficacy of anthelmintic agents in vitro

open access: yesБюллетень сибирской медицины
Aim. To develop a new method to determine the viability of Opisthorchis felineus in vitro using the MTS reagent and to evaluate its applicability for analyzing the efficacy of anthelmintic agents in the treatment of opisthorchiasis.Materials and methods.
E. A. Perina   +7 more
doaj   +1 more source

Schistosomiasis Chemotherapy, Chemoprevention, and Vaccines: History, Progress, and Priorities

open access: yesImmunity, Inflammation and Disease
Background Schistosomiasis is a major human disease of public health importance. Freshwater snails serving as intermediary hosts and human interaction with surface water tainted by feces or urine are both necessary components of the transmission cycle ...
Alaa Oqalaa E. Alibrahim   +6 more
doaj   +1 more source

Cucurbita pepo Seed Oil Induces Microsatellite Instability and Tegumental Damage to Schistosoma mansoni Immature and Adult Worms In vitro

open access: yesInfection and Drug Resistance, 2020
Amany Ibrahim Ammar, 1 Amira Fathy Afifi, 1 Abdallah Essa, 2, 3 Asmaa Galal-Khallaf, 4 Mostafa Mohamed Mokhtar, 5 Somaia Shehab-Eldeen, 2, 3 Amany Ahmed Rady 1 1Department of Medical Parasitology, Faculty of Medicine, Menoufia University, Shebin El Kom,
Ammar AI   +6 more
doaj  

A novel sustained-release agent based on disulfide-induced recombinant collagen hydrogels for the prevention and treatment of Schistosoma infections

open access: yesMicrobiology Spectrum
Schistosomiasis is commonly managed using the praziquantel, but it is only effective against adult worms and duration of action is short. Liver fibrosis will worsen if eggs are still present after stopping treatment.
Jie Wang   +12 more
doaj   +1 more source

Interactions of mefloquine with praziquantel in the Schistosoma mansoni mouse model and in vitro [PDF]

open access: yes, 2017
Objectives Mefloquine has interesting antischistosomal properties, hence it might be an attractive partner drug for combination treatment with praziquantel.
Keiser, Jennifer   +2 more
core  

Praziquantel and factor H recruitment differentially affect the susceptibility of Schistosoma mansoni to complement-mediated damage

open access: yesFrontiers in Immunology
BackgroundSchistosomes are highly efficient evaders of human immunity, as evident by their ability to survive in human blood for years. How they protect themselves against the constant attack by a key element of innate immunity, the complement system ...
Anna E. van Beek   +14 more
doaj   +1 more source

Spontaneous Pneumothorax Secondary to Pulmonary Paragonimiasis: A Case Report Highlighting Diagnostic Delay in Eastern Nepal

open access: yesRespirology Case Reports
Paragonimiasis, or oriental lung fluke, a zoonotic disease acquired by consuming raw or undercooked crustaceans such as crabs or snails, can mimic tuberculosis in endemic regions.
Arun Kumar Mahato   +5 more
doaj   +1 more source

The little we know about the pharmacokinetics and pharmacodynamics of praziquantel (racemate and R-enantiomer) [PDF]

open access: yes, 2017
Praziquantel has been the mainstay of schistosomiasis control since 1984 and widely distributed since 2006 through ‘preventive chemotherapy' programmes to school-aged children or at-risk populations.
Delgado-Romero, Petra   +2 more
core  

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