Results 41 to 50 of about 30,204 (224)

The study of base and surface-active substances influence on biopharmaceutical characteristics of suppository with praziquantel

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2016
Acne dermatoses (rosacea, perioral dermatitis, seborrheic dermatitis etc.) are one of the most actual problems in dermatology. Praziquantel is an antiparasitic medication effective towards trematodes, cestodes.
D. M. Romanina, V. V. Gladishev, G. P. Lisyanska   +2 more
doaj   +1 more source

Circulating antigen tests and urine reagent strips for diagnosis of active schistosomiasis in endemic areas [PDF]

, 2015
Background: Point-of-care (POC) tests for diagnosing schistosomiasis include tests based on circulating antigen detection and urine reagent strip tests.
Bossuyt, P.M.M., Gopalakrishna, G., Lamberton, P., Leeflang, M.M.G., Ochodo, E.A., Polman, K., Reitsma, J.B., Spek, B., van Lieshout, L.   +8 more
core   +3 more sources

Low Praziquantel Treatment Coverage for Schistosoma mansoni in Mayuge District, Uganda, Due to the Absence of Treatment Opportunities, Rather Than Systematic Non-Compliance

Tropical Medicine and Infectious Disease, 2018
The World Health Organization (WHO) recommends praziquantel mass drug administration (MDA) to control schistosomiasis in endemic regions. We aimed to quantify recent and lifetime praziquantel coverage, and reasons for non-treatment, at an individual ...
Moses Adriko, Christina L. Faust, Lauren V. Carruthers, Arinaitwe Moses, Edridah M. Tukahebwa, Poppy H. L. Lamberton   +5 more
doaj   +1 more source

Praziquantel and risk of visual disorders: Case series assessment.

PLoS Neglected Tropical Diseases, 2020
IntroductionPraziquantel has been in use by helminthiasis and schistosomiasis control programs for about 30 years. Although deemed to be safe with regard to its adverse drug reaction profile in reference to the product information of Biltricide, the ...
Merhawi Debesai, Mulugeta Russom
doaj   +1 more source

Study of influence of the surface-active substances concentration on releasing of praziquantel from the rectal suppository

Фармацевтичний журнал, 2018
Acne dermatosis (rosacea, perioral dermatitis, seborrheic dermatitis etc.) are one of the most actual problem in dermatology. Praziquantel is an antiparasitic medication effective towards trematodes, cestodes.
D. M. Romanina, I. I. Berdey, V. V. Gladishev, G. P. Lisyanska   +3 more
doaj   +1 more source

Alternatives to Praziquantel for the Prevention and Control of Schistosomiasis.

ACS Infectious Diseases, 2020
Schistosomiasis, a neglected tropical disease provoked by infection with parasitic blood flukes of the genus Schistosoma, affects almost 240 million people worldwide, and more than 700 million people live in endemic areas.
T. Spangenberg
semanticscholar   +1 more source

Does the presence of praziquantel-related adverse events affect the health community's perception toward the mass chemopreventive program in the highest prevalence area of Schistosomiasis in Indonesia? Study in Dodolo village, Napu Valley, Central Sulawesi

Gaceta Sanitaria, 2021
Objective: This study was to determine the relationship between a praziquantel-related adverse event with the health community perception to chemopreventive of Schistosomiasis in Dodolo village, Napu Valley, Central Sulawesi.
Ayu Sekarani Damana Putri, T. Vera Diana, Rahma Daris, Fitri Afriana, Serli Hatul Hidayat   +4 more
doaj   +1 more source

Transcriptional responses of in vivo praziquantel exposure in schistosomes identifies a functional role for calcium signalling pathway member CamKII. [PDF]

PLoS Pathogens, 2013
Treatment for clinical schistosomiasis has relied centrally on the broad spectrum anthelmintic praziquantel; however, there is limited information on its mode of action or the molecular response of the parasite.
Hong You, Donald P McManus, Wei Hu, Michael J Smout, Paul J Brindley, Geoffrey N Gobert   +5 more
doaj   +1 more source

Drug metabolism and pharmacokinetics of praziquantel: A review of variable drug exposure during schistosomiasis treatment in human hosts and experimental models

PLoS Neglected Tropical Diseases, 2020
Schistosomiasis control is heavily reliant on the drug praziquantel (PZQ), which is used as preventive chemotherapy as part of national helminth control strategies. Given the heavy reliance on PZQ for mass drug administration, there has been considerable
Grace Zdesenko, F. Mutapi
semanticscholar   +1 more source

Efficacy and safety of praziquantel, tribendimidine and mebendazole in patients with co-infection of Clonorchis sinensis and other helminths. [PDF]

PLoS Neglected Tropical Diseases, 2014
BackgroundBoth tribendimidine and mebendazole are broad-spectrum drugs for anti-intestinal nematodes. We aim to assess the efficacy and safety of tribendimidine and mebendazole in patients with co-infection of Clonorchis sinensis and other helminths ...
Li-Li Xu, Bin Jiang, Ji-Hui Duan, Shi-Feng Zhuang, Yong-Chun Liu, Shi-Qiao Zhu, Li-Ping Zhang, Hao-Bing Zhang, Shu-Hua Xiao, Xiao-Nong Zhou   +9 more
doaj   +1 more source