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Schistosomiasis is a neglected tropical disease caused by blood-dwelling flukes of the genus Schistosoma. While the disease may affect as many as 249 million people, treatment largely relies on a single drug, praziquantel.
Ibrahim N. Mwangi+6 more
doaj +1 more source
Development of a field diagnostic tool for Schistosoma mansoni Praziquantel resistant markers in selected endemic communities [PDF]
Schistosomiasis is a neglected tropical disease that affects more than 200 million people and 45% of infections have been shown to occur in school-aged children. A large percentage of the disease burden lies in Africa. In 2012, the WHO outlined a roadmap
Maame Ekua Acquah+3 more
doaj +3 more sources
In Vitro Cestocidal Activity of Thymol on Mesocestoides corti Tetrathyridia and Adult Worms [PDF]
Nothing is known about the possible effect of thymol or other compounds of essential oils against the adult worms of cestodes. The aim of the present work was to determine in vitro cestodicidal activity of thymol against Mesocestoides corti adult worms ...
Elissondo, María Celina+1 more
core +1 more source
The immune-dependence of chemotherapy in experimental schistosomiasis
Experimental evidence indicates that immune effector mechanisms can enhance the activity of schistosomicidal drugs. Praziquantel, oxamniquine, hycanthone and antimony were less effective against Schistosoma mansoni infections in mice immunosuppressed by ...
M. J. Doenhoff
doaj +1 more source
Resisting control of neglected tropical diseases: dilemmas in the mass treatment of schistosomiasis and soil-transmitted helminths in north-west Uganda [PDF]
A strong case has recently been made by academics and policymakers to develop national programmes for the integrated control of Africa’s ‘neglected tropical diseases’.
Allen, Tim+2 more
core +1 more source
Thioxanthone: A Benchmark Photocatalyst for Organic Synthesis
Thioxanthone is a highly versatile and effective organocatalyst for photochemical applications, with its low‐toxicity, metal‐free structure driving growing interest in sustainable photocatalysis. Building on our previous 2021 review, this update covers advances from 2021–2025 in thioxanthone‐based synthetic organic photochemistry – excluding ...
Vera P. Demertzidou+2 more
wiley +1 more source
BackgroundDespite the reported success in reducing morbidity, praziquantel alone is insufficient for the control and elimination of schistosomiasis, partly due to its poor efficacy against the juvenile worms. Artemisinin derivatives are effective against
Rajabu Hussein Mnkugwe+4 more
doaj +1 more source
“Rapid-Impact Interventions”: How a Policy of Integrated Control for Africa's Neglected Tropical Diseases Could Benefit the Poor [PDF]
Controlling seven tropical infections in Africa would cost just 40 cents per person per year, and would permanently benefit hundreds of millions of ...
Alan Fenwick+14 more
core +4 more sources
Abstract We reported for the first time a confirmed case of equine fasciolosis in the Community of Madrid (Spain). Here, we described the clinical presentation, diagnostic approach and treatment of the affected horse, as well as the seroprevalence of Fasciola hepatica in the equestrian centre where it was detected.
Carolina R. Sanz+3 more
wiley +1 more source
Over the past decade, a significant reduction in the prevalence of schistosomiasis has been achieved, partially explained by the large-scale administration of praziquantel.
Jean T. Coulibaly+5 more
doaj +1 more source