Results 41 to 50 of about 29,845 (261)

Praziquantel decreases fecundity in Schistosoma mansoni adult worms that survive treatment: evidence from a laboratory life-history trade-offs selection study

open access: yesInfectious Diseases of Poverty, 2017
Background Mass drug administration of praziquantel is the World Health Organization’s endorsed control strategy for schistosomiasis. A decade of annual treatments across sub-Saharan Africa has resulted in significant reductions of infection prevalence ...
Poppy H.L. Lamberton   +2 more
doaj   +1 more source

Are we ready for Taenia solium cysticercosis elimination in sub-Saharan Africa? [PDF]

open access: yes, 2016
The World Health Organization announced in November 2014 at the fourth international meeting on 'the control of neglected zoonotic diseases - from advocacy to action', that intervention tools for eliminating Taenia solium taeniosis/cysticercosis (TSTC ...
Braae, Uffe Christian   +4 more
core   +3 more sources

Efficacy of Praziquantel for the Treatment of Human Schistosomiasis in Ethiopia: A Systematic Review and Meta-Analysis

open access: yesJournal of Tropical Medicine, 2021
Background. Schistosomiasis is one of the neglected tropical diseases causing a serious human health problem in Ethiopia. Praziquantel is the only drug that has been used for the treatment of human schistosomiasis in the country.
Tamirat Hailegebriel   +2 more
doaj   +1 more source

Sensitivity and specificity of a urine circulating anodic antigen test for the diagnosis of Schistosoma haematobium in low endemic settings [PDF]

open access: yes, 2015
Elimination of schistosomiasis as a public health problem and interruption of transmission in selected areas are key goals of the World Health Organization for 2025.
Ali, Said M.   +10 more
core   +3 more sources

Safety of topical administration of fluralaner plus moxidectin concurrently with praziquantel in cats

open access: yesParasites & Vectors, 2018
Background Fluralaner provides efficacy against feline ectoparasites following topical administration. Moxidectin is routinely used to treat gastrointestinal nematode infections and prevent heartworm disease caused by Dirofilaria immitis. Praziquantel is
Feli M. Walther   +2 more
doaj   +1 more source

Praziquantel sensitivity of Kenyan Schistosoma mansoni isolates and the generation of a laboratory strain with reduced susceptibility to the drug

open access: yesInternational Journal for Parasitology: Drugs and Drug Resistance, 2014
Schistosomiasis is a neglected tropical disease caused by blood-dwelling flukes of the genus Schistosoma. While the disease may affect as many as 249 million people, treatment largely relies on a single drug, praziquantel.
Ibrahim N. Mwangi   +6 more
doaj   +1 more source

Opportunities and challenges for modelling epidemiological and evolutionary dynamics in a multihost, multiparasite system: Zoonotic hybrid schistosomiasis in West Africa [PDF]

open access: yes, 2017
Multihost multiparasite systems are evolutionarily and ecologically dynamic, which presents substantial trans‐disciplinary challenges for elucidating their epidemiology and designing appropriate control.
Borlase, A, Rudge, J W, Webster, J P
core   +3 more sources

Development of a field diagnostic tool for Schistosoma mansoni Praziquantel resistant markers in selected endemic communities [PDF]

open access: yesResearch Ideas and Outcomes
Schistosomiasis is a neglected tropical disease that affects more than 200 million people and 45% of infections have been shown to occur in school-aged children. A large percentage of the disease burden lies in Africa. In 2012, the WHO outlined a roadmap
Maame Ekua Acquah   +3 more
doaj   +3 more sources

Reduced efficacy of praziquantel against Schistosoma mansoniis associated with multiple rounds of mass drug administration [PDF]

open access: yes, 2016
Background: Mass drug administration (MDA) with praziquantel is the cornerstone of schistosomiasis control in sub-Saharan Africa. The effectiveness of this strategy is dependent on the continued high efficacy of praziquantel; however, drug efficacy is ...
Cotton, James A.   +6 more
core   +4 more sources

The immune-dependence of chemotherapy in experimental schistosomiasis

open access: yesMemorias do Instituto Oswaldo Cruz, 1989
Experimental evidence indicates that immune effector mechanisms can enhance the activity of schistosomicidal drugs. Praziquantel, oxamniquine, hycanthone and antimony were less effective against Schistosoma mansoni infections in mice immunosuppressed by ...
M. J. Doenhoff
doaj   +1 more source

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