Results 21 to 30 of about 23,001 (237)

Praziquantel and risk of visual disorders: Case series assessment.

PLoS Neglected Tropical Diseases, 2020
IntroductionPraziquantel has been in use by helminthiasis and schistosomiasis control programs for about 30 years. Although deemed to be safe with regard to its adverse drug reaction profile in reference to the product information of Biltricide, the ...
Merhawi Debesai, Mulugeta Russom
doaj   +1 more source

Evaluation of the antiparasitic efficacy of praziquantel against Prohemistomum vivax (Cyathocotylidae) metacercariae in naturally infected African catfish (Clarias gariepinus). [PDF]

Sci Rep
Abdelsalam M, Abdelkhalek S, Korany RMS, Ibrahim MA, Abdel-Moneam DA, Warda M, Shadidizaji A, Attia MM.   +7 more
europepmc   +3 more sources

Praziquantel efficacy and post-treatment reinfection and incidence of Schistosoma mansoni among school-aged children in Northern Uganda: a 24-week cohort study in a high transmission focus. [PDF]

BMC Infect Dis
Byagamy JP, Opiro R, Nyafwono M, Angwech H, Malinga GM, Echodu R, Odongo-Aginya EI.   +6 more
europepmc   +4 more sources

Study of influence of the surface-active substances concentration on releasing of praziquantel from the rectal suppository

Фармацевтичний журнал, 2018
Acne dermatosis (rosacea, perioral dermatitis, seborrheic dermatitis etc.) are one of the most actual problem in dermatology. Praziquantel is an antiparasitic medication effective towards trematodes, cestodes.
D. M. Romanina, I. I. Berdey, V. V. Gladishev, G. P. Lisyanska   +3 more
doaj   +1 more source

Resolution of Praziquantel

PLoS Neglected Tropical Diseases, 2011
Praziquantel remains the drug of choice for the worldwide treatment and control of schistosomiasis. The drug is synthesized and administered as a racemate. Use of the pure active enantiomer would be desirable since the inactive enantiomer is associated with side effects and is responsible for the extremely bitter taste of the pill.We have identified ...
Michael Woelfle, Jean-Paul Seerden, Jesse de Gooijer, Kees Pouwer, Piero Olliaro, Matthew H Todd   +5 more
openaire   +4 more sources

Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on intensity of infection and antibody responses to schistosome antigens: results of a randomised, placebo-controlled trial. [PDF]

, 2009
BACKGROUND: Praziquantel treatment of schistosomiasis during pregnancy was only recommended in 2002; hence the effects of treatment during pregnancy are not fully known. We have therefore evaluated the effects on infection intensity and the immunological
Emojong Nicholas O, Dunne, David W., Mawa, Patrice A, Birgitte J Vennervald, Jones Frances M, Jones, Frances M., Duong, Trinh, Patrice A Mawa, Emojong, Nicholas O., Vennervald, Birgitte J, Mawa Patrice A, Frances M Jones, Alison M Elliott, Trinh Duong, Mpairwe Harriet, Elliott, Alison M, Robert Tweyongyere, Mawa, Patrice A., Mpairwe, Harriet, Emojong, Nicholas O, Dunne, David W, Katunguka-Rwakishaya Eli, Elliott Alison M, Tweyongyere, Robert, David W Dunne, Katunguka-Rwakishaya, Eli, Dunne David W, Elliott, Alison M., Duong Trinh, Vennervald Birgitte J, Nicholas O Emojong, Eli Katunguka-Rwakishaya, Tweyongyere Robert, Jones, Frances M, Harriet Mpairwe   +34 more
core   +1 more source

Toward measuring Schistosoma response to praziquantel treatment with appropriate descriptors of egg excretion [PDF]

, 2015
The control of schistosomiasis emphasizes preventive chemotherapy with praziquantel, which aims at decreasing infection intensity and thus morbidity in individuals, as well as transmission in communities.
Xiao-Nong Zhou (92570), Jennifer Keiser, Utzinger, Jürg, Michel Vaillant, King, Charles H., Jean T Coulibaly, Piero L. Olliaro (217564), José Carlos Sousa-Figueiredo (173724), Stefanie Knopp, Katarina Stete (213207), Olliaro, Piero L, Eliézer K. N’Goran (417750), Jean T. Coulibaly (108845), Jennifer Keiser (39606), Xiao-Nong Zhou, Garba, Amadou, Zhou, Xiao-Nong, Aly Landouré, Aly Landouré (264317), Olliaro, Piero L., Amadou Garba (125686), Landouré, Aly, Jürg Utzinger (39609), Stefanie Knopp (108848), Michel Vaillant (39101), Diawara, Aïssatou, Scherrer, Alexandra U, Amadou Garba, Coulibaly, Jean Tenena, Charles H. King (78462), Vaillant, Michel, Piero L Olliaro, Coulibaly, Jean T., Aïssatou Diawara, Scherrer, Alexandra U., King, Charles H, Sousa-Figueiredo, José Carlos, Katarina Stete, Charles H King, Alexandra U Scherrer, N’Goran, Eliézer K., Stete, Katarina, José Carlos Sousa-Figueiredo, Jürg Utzinger, Giovanna Raso, Giovanna Raso (51489), Alexandra U. Scherrer (214775), Raso, Giovanna, Coulibaly, Jean T, Aïssatou Diawara (5654983), Eliézer K N'Goran, Keiser, Jennifer, N'Goran, Eliézer K., Knopp, Stefanie, N'Goran, Eliézer K   +54 more
core   +2 more sources

New approaches to measuring anthelminthic drug efficacy : parasitological responses of childhood schistosome infections to treatment with praziquantel [PDF]

, 2015
By 2020, the global health community aims to control and eliminate human helminthiases, including schistosomiasis in selected African countries, principally by preventive chemotherapy (PCT) through mass drug administration (MDA) of anthelminthics ...
Scherrer, A U, Raso, G, Utzinger, Jürg, Alexandra U. Scherrer, King, Charles H., Coulibaly, Jean T., Walker, Martin, Basanez, MG, Jean T. Coulibaly, Basáñez, M-G, King, CH, Martin Walker, Walker, M, Scherrer, Alexandra U., Sousa-Figueiredo, José Carlos, Katarina Stete, Mabud, Tarub S., Mabud, T, Stete, Katarina, Basáñez, Maria-Gloria, Coulibaly, J T, José Carlos Sousa-Figueiredo, Jürg Utzinger, Maria-Gloria Basáñez, Utzinger, J, Giovanna Raso, Scherrer, AU, Raso, Giovanna, Olliaro, Piero L., Stothard, JR, Stothard, J R, Sousa-Figueiredo, J C, Olliaro, PL, Coulibaly, JT, Sousa-Figueiredo, JC, Stothard, J. Russell, Charles H. King, King, C H, J. Russell Stothard, Tarub S. Mabud, Piero L. Olliaro, Olliaro, P L, Stete, K   +42 more
core   +1 more source

Transcriptional responses of in vivo praziquantel exposure in schistosomes identifies a functional role for calcium signalling pathway member CamKII. [PDF]

PLoS Pathogens, 2013
Treatment for clinical schistosomiasis has relied centrally on the broad spectrum anthelmintic praziquantel; however, there is limited information on its mode of action or the molecular response of the parasite.
Hong You, Donald P McManus, Wei Hu, Michael J Smout, Paul J Brindley, Geoffrey N Gobert   +5 more
doaj   +1 more source

Praziquantel: its use in control of schistosomiasis in sub-Saharan Africa and current research needs [PDF]

, 2009
Treatment with praziquantel (PZQ) has become virtually the sole basis of schistosomiasis control in sub-Saharan Africa and elsewhere, and the drug is reviewed here in the context of the increasing rate that it is being used for this purpose. Attention is
Doenhoff, M.J., Southgate, V., Botros, S., Pica-Mattocia, L., Hagan, P., Coles, G., Tchuem, T.C.H.U., Mbaye, A., Engels, D., Cioli, D.   +9 more
core   +1 more source