Results 21 to 30 of about 19,502 (213)

Solid dispersions with hydrogenated castor oil increase solubility, dissolution rate and intestinal absorption of praziquantel

Brazilian Journal of Pharmaceutical Sciences, 2010
The solubility behavior of drugs remains one of the most challenging aspects in formulation development. Solid Dispersion (SD) has tremendous potential for improving drug solubility.
Marco Vinicius Chaud, Pollyanna Tamascia, Andréa Cristina de Lima, Maria Ondina Paganelli, Maria Palmira Daflon Gremião, Osvaldo de Freitas   +5 more
doaj   +1 more source

Praziquantel

Reactions Weekly, 2006
europepmc   +4 more sources

Co-crystals of Praziquantel: Discovery by Network-Based Link Prediction [PDF]

, 2021
In this study, co-crystals for Praziquantel (PZQ), an anthelmintic drug used to treat schistosomiasis, are predicted with network-based link prediction.
Elias, Vlieg, Paul, Tinnemans, Valérie, Dupray, Jan-Joris, Devogelaer, Hugo, Meekes, Maxime D., Charpentier, Joop H., ter Horst, Arnoud, Tijink, Gérard, Coquerel, Karen, Johnston, Rene, de Gelder   +10 more
core   +2 more sources

The study of base and surface-active substances influence on biopharmaceutical characteristics of suppository with praziquantel

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2016
Acne dermatoses (rosacea, perioral dermatitis, seborrheic dermatitis etc.) are one of the most actual problems in dermatology. Praziquantel is an antiparasitic medication effective towards trematodes, cestodes.
D. M. Romanina, V. V. Gladishev, G. P. Lisyanska   +2 more
doaj   +1 more source

Single oral fixed-dose praziquantel-miltefosine nanocombination for effective control of experimental schistosomiasis mansoni

Parasites & Vectors, 2020
Background The control of schistosomiasis has been centered to date on a single drug, praziquantel, with shortcomings including treatment failure, reinfection, and emergence of drug resistance. Drug repurposing, combination therapy or nanotechnology were
Maha M. Eissa, Mervat Z. El-Azzouni, Labiba K. El-Khordagui, Amany Abdel Bary, Riham M. El-Moslemany, Sara A. Abdel Salam   +5 more
doaj   +1 more source

Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on intensity of infection and antibody responses to schistosome antigens: results of a randomised, placebo-controlled trial. [PDF]

, 2009
BACKGROUND: Praziquantel treatment of schistosomiasis during pregnancy was only recommended in 2002; hence the effects of treatment during pregnancy are not fully known. We have therefore evaluated the effects on infection intensity and the immunological
Emojong Nicholas O, Dunne, David W., Mawa, Patrice A, Birgitte J Vennervald, Jones Frances M, Jones, Frances M., Duong, Trinh, Patrice A Mawa, Emojong, Nicholas O., Vennervald, Birgitte J, Mawa Patrice A, Frances M Jones, Alison M Elliott, Trinh Duong, Mpairwe Harriet, Elliott, Alison M, Robert Tweyongyere, Mawa, Patrice A., Mpairwe, Harriet, Emojong, Nicholas O, Dunne, David W, Katunguka-Rwakishaya Eli, Elliott Alison M, Tweyongyere, Robert, David W Dunne, Katunguka-Rwakishaya, Eli, Dunne David W, Elliott, Alison M., Duong Trinh, Vennervald Birgitte J, Nicholas O Emojong, Eli Katunguka-Rwakishaya, Tweyongyere Robert, Jones, Frances M, Harriet Mpairwe   +34 more
core   +1 more source

IMMUNOLOGICAL AND HEMATOLOGICAL CHANGES AFTER PRAZIQUANTEL TREATMENT IN DEN INDUCED HEPATIC NEOPLASIA IN RATS [PDF]

Assiut Veterinary Medical Journal, 1993
Praziquantel, the commonly used anti--schistosomal drug, was investigated for hepatic carcinogenesis promoting potential using Diethylnitrosamine (DEN) - induced hepatic neoplasia in rats as a model in our study. Fity rats were given a daily dose of 5 mg/
M.T. SHATA, M. TAHA, A. SH. SEDDEK
doaj   +1 more source

Efficacy and safety of praziquantel in preschool-aged children in an area co-endemic for Schistosoma mansoni and S. haematobium [PDF]

, 2012
BACKGROUND: In sub-Saharan Africa the recommended strategy to control schistosomiasis is preventive chemotherapy. Emphasis is placed on school-aged children, but in high endemicity areas, preschool-aged children are also at risk, and hence might need ...
N'Gbesso, Y. K., N'Goran, E. K., Coulibaly, J. T., Knopp, S., Jennifer Keiser, Eliézer K. N'Goran (108853), Keiser, J., Utzinger, J., Jürg Utzinger (39609), Jean T Coulibaly, Yve K N'gbesso, Stefanie Knopp (108848), Stefanie Knopp, Yve K. N'Gbesso (113126), Eliézer K N'Goran, Jean T. Coulibaly (108845), Jennifer Keiser (39606), Jürg Utzinger, N'gbesso YK, N'Goran Eliézer K., Keiser J, Knopp S, Utzinger J, N'Goran EK, Utzinger Jürg, Coulibaly Jean T., Keiser Jennifer, N'Gbesso Yve K., Knopp Stefanie, Coulibaly JT   +29 more
core   +1 more source

Low Praziquantel Treatment Coverage for Schistosoma mansoni in Mayuge District, Uganda, Due to the Absence of Treatment Opportunities, Rather Than Systematic Non-Compliance

Tropical Medicine and Infectious Disease, 2018
The World Health Organization (WHO) recommends praziquantel mass drug administration (MDA) to control schistosomiasis in endemic regions. We aimed to quantify recent and lifetime praziquantel coverage, and reasons for non-treatment, at an individual ...
Moses Adriko, Christina L. Faust, Lauren V. Carruthers, Arinaitwe Moses, Edridah M. Tukahebwa, Poppy H. L. Lamberton   +5 more
doaj   +1 more source

Praziquantel and risk of visual disorders: Case series assessment.

PLoS Neglected Tropical Diseases, 2020
IntroductionPraziquantel has been in use by helminthiasis and schistosomiasis control programs for about 30 years. Although deemed to be safe with regard to its adverse drug reaction profile in reference to the product information of Biltricide, the ...
Merhawi Debesai, Mulugeta Russom
doaj   +1 more source