Results 11 to 20 of about 12,135 (168)

Paragonimiasis Following Ingestion of Frozen Freshwater Crab: Two Case Reports. [PDF]

Respirol Case Rep
Paragonimiasis is a zoonotic trematode infection acquired through ingestion of freshwater crustaceans or raw game meat. Here, we report two patients (a couple) who developed paragonimiasis after consuming previously frozen freshwater crabs together at the same restaurant in Tokyo.
Yamamura A, Sekiya M, Usui Y, Sakamoto S, Watanabe K, Fukuda K, Kurose Y, Tochigi N, Kokubo M, Maruyama H, Kishi K.   +10 more
europepmc   +2 more sources

Praziquantel and risk of visual disorders: Case series assessment.

PLoS Neglected Tropical Diseases, 2020
IntroductionPraziquantel has been in use by helminthiasis and schistosomiasis control programs for about 30 years. Although deemed to be safe with regard to its adverse drug reaction profile in reference to the product information of Biltricide, the ...
Merhawi Debesai, Mulugeta Russom
doaj   +1 more source

Efficacy and Safety of Moxidectin, Synriam, Synriam-Praziquantel versus Praziquantel against Schistosoma haematobium and S. mansoni Infections: A Randomized, Exploratory Phase 2 Trial. [PDF]

PLoS Neglected Tropical Diseases, 2016
BACKGROUND:Schistosomiasis affects millions of people, yet treatment options are limited. The antimalarial Synriam (piperaquine 150 mg/arterolane 750 mg) and the anthelminthic moxidectin revealed promising antischistosomal properties in preclinical or ...
Beatrice Barda, Jean T Coulibaly, Maxim Puchkov, Jörg Huwyler, Jan Hattendorf, Jennifer Keiser   +5 more
doaj   +1 more source

Study of influence of the surface-active substances concentration on releasing of praziquantel from the rectal suppository

Фармацевтичний журнал, 2018
Acne dermatosis (rosacea, perioral dermatitis, seborrheic dermatitis etc.) are one of the most actual problem in dermatology. Praziquantel is an antiparasitic medication effective towards trematodes, cestodes.
D. M. Romanina, I. I. Berdey, V. V. Gladishev, G. P. Lisyanska   +3 more
doaj   +1 more source

Overcoming Cognitive Bias: A Case of Disseminated Neurocysticercosis in a Muslim Woman With Remote Pork Consumption. [PDF]

Clin Case Rep
ABSTRACT Religious prohibitions against pork do not exclude individuals residing in endemic regions from contracting neurocysticercosis. Obtaining a detailed lifetime exposure history, including prior religious and dietary practices, is essential to overcome cognitive bias and prevent diagnostic delays.
Nnang JYB, Takoutsing B, Dongmo A, Tsilla JA, Mvuchiim B, Numfor R, Randall MFN, Aka E, Esene I.   +8 more
europepmc   +2 more sources

Praziquantel, mefloquine-praziquantel, and mefloquine-artesunate-praziquantel against Schistosoma haematobium: a randomized, exploratory, open-label trial.

PLoS Neglected Tropical Diseases, 2014
BackgroundTreatment and morbidity control of schistosomiasis relies on a single drug, praziquantel. Hence, there is a pressing need to develop additional therapeutics against schistosomiasis.
Jennifer Keiser, Kigbafori D Silué, Lukas K Adiossan, Nicaise A N'Guessan, N'Chou Monsan, Jürg Utzinger, Eliézer K N'Goran   +6 more
doaj   +1 more source

Resolution of Praziquantel

PLoS Neglected Tropical Diseases, 2011
Praziquantel remains the drug of choice for the worldwide treatment and control of schistosomiasis. The drug is synthesized and administered as a racemate. Use of the pure active enantiomer would be desirable since the inactive enantiomer is associated with side effects and is responsible for the extremely bitter taste of the pill.We have identified ...
Michael Woelfle, Jean-Paul Seerden, Jesse de Gooijer, Kees Pouwer, Piero Olliaro, Matthew H Todd   +5 more
openaire   +4 more sources

Does the presence of praziquantel-related adverse events affect the health community's perception toward the mass chemopreventive program in the highest prevalence area of Schistosomiasis in Indonesia? Study in Dodolo village, Napu Valley, Central Sulawesi

Gaceta Sanitaria, 2021
Objective: This study was to determine the relationship between a praziquantel-related adverse event with the health community perception to chemopreventive of Schistosomiasis in Dodolo village, Napu Valley, Central Sulawesi.
Ayu Sekarani Damana Putri, T. Vera Diana, Rahma Daris, Fitri Afriana, Serli Hatul Hidayat   +4 more
doaj   +1 more source

Transcriptional responses of in vivo praziquantel exposure in schistosomes identifies a functional role for calcium signalling pathway member CamKII. [PDF]

PLoS Pathogens, 2013
Treatment for clinical schistosomiasis has relied centrally on the broad spectrum anthelmintic praziquantel; however, there is limited information on its mode of action or the molecular response of the parasite.
Hong You, Donald P McManus, Wei Hu, Michael J Smout, Paul J Brindley, Geoffrey N Gobert   +5 more
doaj   +1 more source

Efficacy of praziquantel and artemisinin derivatives for the treatment and prevention of human schistosomiasis: a systematic review and meta-analysis

Parasites & Vectors, 2011
Background Praziquantel has been used as first-line drug for chemotherapy of schistosomiasis since 1984. Besides praziquantel, artemether and artesunate have also been used for the control of this infectious disease since late 1990s.
Zhao Qin-Ping, Guo Yi, Dong Hui-Fen, Liu Rong, Jiang Ming-Sen   +4 more
doaj   +1 more source