The effects of subcurative praziquantel treatment on life-history traits and trade-offs in drug-resistant Schistosoma mansoni [PDF]
, 2016 Natural selection acts on all organisms, including parasites, to maximise reproductive fitness. Drug resistance traits are often associated with life-history costs in the absence of treatment.
Viana, Mafalda +4 more
core +14 more sources
Reduced efficacy of praziquantel against Schistosoma mansoniis associated with multiple rounds of mass drug administration [PDF]
, 2016 Background: Mass drug administration (MDA) with praziquantel is the cornerstone of schistosomiasis control in sub-Saharan Africa. The effectiveness of this strategy is dependent on the continued high efficacy of praziquantel; however, drug efficacy is ...
Cotton, James A. +6 more
core +5 more sources
Фармацевтичний журнал, 2018 Acne dermatosis (rosacea, perioral dermatitis, seborrheic dermatitis etc.) are one of the most actual problem in dermatology. Praziquantel is an antiparasitic medication effective towards trematodes, cestodes.
D. M. Romanina +3 more
doaj +1 more source
Praziquantel and risk of visual disorders: Case series assessment.
PLoS Neglected Tropical Diseases, 2020 IntroductionPraziquantel has been in use by helminthiasis and schistosomiasis control programs for about 30 years. Although deemed to be safe with regard to its adverse drug reaction profile in reference to the product information of Biltricide, the ...
Merhawi Debesai, Mulugeta Russom
doaj +1 more source
PLoS Neglected Tropical Diseases, 2014 BackgroundTreatment and morbidity control of schistosomiasis relies on a single drug, praziquantel. Hence, there is a pressing need to develop additional therapeutics against schistosomiasis.
Jennifer Keiser +6 more
doaj +1 more source
Efficacy and safety of praziquantel, tribendimidine and mebendazole in patients with co-infection of Clonorchis sinensis and other helminths. [PDF]
PLoS Neglected Tropical Diseases, 2014 BackgroundBoth tribendimidine and mebendazole are broad-spectrum drugs for anti-intestinal nematodes. We aim to assess the efficacy and safety of tribendimidine and mebendazole in patients with co-infection of Clonorchis sinensis and other helminths ...
Li-Li Xu +9 more
doaj +1 more source
The effect of anthelmintic treatment during pregnancy on HIV plasma viral load: results from a randomized, double-blind, placebo-controlled trial in Uganda. [PDF]
, 2012 BACKGROUND: To investigate the effect of helminth infections and their treatment during pregnancy on HIV load, we conducted a 2 × 2 factorial randomized controlled trial of albendazole versus placebo and praziquantel versus placebo in pregnant women in ...
Elliott, Alison M +8 more
core +1 more source
Transcriptional responses of in vivo praziquantel exposure in schistosomes identifies a functional role for calcium signalling pathway member CamKII. [PDF]
PLoS Pathogens, 2013 Treatment for clinical schistosomiasis has relied centrally on the broad spectrum anthelmintic praziquantel; however, there is limited information on its mode of action or the molecular response of the parasite.
Hong You +5 more
doaj +1 more source
Gaceta Sanitaria, 2021 Objective: This study was to determine the relationship between a praziquantel-related adverse event with the health community perception to chemopreventive of Schistosomiasis in Dodolo village, Napu Valley, Central Sulawesi.
Ayu Sekarani Damana Putri +4 more
doaj +1 more source
In Vitro Cestocidal Activity of Thymol on Mesocestoides corti Tetrathyridia and Adult Worms [PDF]
, 2014 Nothing is known about the possible effect of thymol or other compounds of essential oils against the adult worms of cestodes. The aim of the present work was to determine in vitro cestodicidal activity of thymol against Mesocestoides corti adult worms ...
Elissondo, María Celina +1 more
core +1 more source