Results 11 to 20 of about 17,340 (213)

Praziquantel, mefloquine-praziquantel, and mefloquine-artesunate-praziquantel against Schistosoma haematobium: a randomized, exploratory, open-label trial. [PDF]

PLoS Neglected Tropical Diseases, 2014
BackgroundTreatment and morbidity control of schistosomiasis relies on a single drug, praziquantel. Hence, there is a pressing need to develop additional therapeutics against schistosomiasis.
Jennifer Keiser, Kigbafori D Silué, Lukas K Adiossan, Nicaise A N'Guessan, N'Chou Monsan, Jürg Utzinger, Eliézer K N'Goran   +6 more
doaj   +2 more sources

Efficacy and Safety of Moxidectin, Synriam, Synriam-Praziquantel versus Praziquantel against Schistosoma haematobium and S. mansoni Infections: A Randomized, Exploratory Phase 2 Trial. [PDF]

PLoS Neglected Tropical Diseases, 2016
BACKGROUND:Schistosomiasis affects millions of people, yet treatment options are limited. The antimalarial Synriam (piperaquine 150 mg/arterolane 750 mg) and the anthelminthic moxidectin revealed promising antischistosomal properties in preclinical or ...
Beatrice Barda, Jean T Coulibaly, Maxim Puchkov, Jörg Huwyler, Jan Hattendorf, Jennifer Keiser   +5 more
doaj   +3 more sources

Praziquantel

Reactions Weekly, 2017
Praziquantel-originally EMBAY 8440-was developed and subsequently marketed by Bayer as Biltricide (McMahon, 1981). It is a pyrazinoisoquinoline derivative, with the full chemical name of 2-cyclo-hexylcarbonyl-1,2,3,6,7,11bhexahydro- 4H-pyrazino[2,1-a ...
Bartley, Paul B.
openaire   +2 more sources

Paragonimiasis Following Ingestion of Frozen Freshwater Crab: Two Case Reports. [PDF]

Respirol Case Rep
Paragonimiasis is a zoonotic trematode infection acquired through ingestion of freshwater crustaceans or raw game meat. Here, we report two patients (a couple) who developed paragonimiasis after consuming previously frozen freshwater crabs together at the same restaurant in Tokyo.
Yamamura A, Sekiya M, Usui Y, Sakamoto S, Watanabe K, Fukuda K, Kurose Y, Tochigi N, Kokubo M, Maruyama H, Kishi K.   +10 more
europepmc   +2 more sources

Overcoming Cognitive Bias: A Case of Disseminated Neurocysticercosis in a Muslim Woman With Remote Pork Consumption. [PDF]

Clin Case Rep
ABSTRACT Religious prohibitions against pork do not exclude individuals residing in endemic regions from contracting neurocysticercosis. Obtaining a detailed lifetime exposure history, including prior religious and dietary practices, is essential to overcome cognitive bias and prevent diagnostic delays.
Nnang JYB, Takoutsing B, Dongmo A, Tsilla JA, Mvuchiim B, Numfor R, Randall MFN, Aka E, Esene I.   +8 more
europepmc   +2 more sources

The Anthelmintic Activity of Praziquantel Analogs Correlates with Structure-Activity Relationships at TRPMPZQ Orthologs. [PDF]

, 2023
The anthelmintic drug praziquantel remains a key clinical therapy for treating various diseases caused by parasitic flatworms. The parasite target of praziquantel has remained undefined despite longstanding usage in the clinic, although a candidate ion ...
Rohr, Claudia M, Sprague, Daniel J, Harris, Jade L, Marchant, Jonathan S, Park, Sang-Kyu, Lundström-Stadelmann, Britta, Maillard, David, Spangenberg, Thomas, Kaethner, Marc   +8 more
core   +1 more source

Efficacy and safety of praziquantel in preschool-aged children in an area co-endemic for Schistosoma mansoni and S. haematobium [PDF]

, 2012
BACKGROUND: In sub-Saharan Africa the recommended strategy to control schistosomiasis is preventive chemotherapy. Emphasis is placed on school-aged children, but in high endemicity areas, preschool-aged children are also at risk, and hence might need ...
N'Gbesso, Y. K., N'Goran, E. K., Coulibaly, J. T., Knopp, S., Jennifer Keiser, Eliézer K. N'Goran (108853), Keiser, J., Utzinger, J., Jürg Utzinger (39609), Jean T Coulibaly, Yve K N'gbesso, Stefanie Knopp (108848), Stefanie Knopp, Yve K. N'Gbesso (113126), Eliézer K N'Goran, Jean T. Coulibaly (108845), Jennifer Keiser (39606), Jürg Utzinger   +17 more
core   +1 more source

Dynamics of Schistosoma haematobium egg output and associated infection parameters following treatment with praziquantel in school-aged children [PDF]

, 2012
BACKGROUND: Praziquantel is the drug of choice in preventive chemotherapy targeting schistosomiasis. Increasing large-scale administration of praziquantel requires monitoring of drug efficacy to detect early signs of development of resistance.
Lohourignon Laurent K, Krauth, Stefanie J., Utzinger, Jürg, Coulibaly, Jean T., Jean T Coulibaly, Katarina Stete, Stefanie Knopp, Utzinger Jürg, N’Goran, Eliézer K., Stete, Katarina, Winfried V Kern, Lohourignon, Laurent K., Ivan Müller, Jürg Utzinger, Hattendorf Jan, Stete Katarina, Stefanie J Krauth, Coulibaly Jean T, Krauth Stefanie J, Müller Ivan, Laurent K Lohourignon, Müller, Ivan, N’Goran Eliézer K, Kern Winfried V, Hattendorf, Jan, N'Goran, Eliézer K., Knopp, Stefanie, Kern, Winfried V., Knopp Stefanie, Eliézer K N’Goran, Jan Hattendorf   +30 more
core   +1 more source

Study of influence of the surface-active substances concentration on releasing of praziquantel from the rectal suppository

Фармацевтичний журнал, 2018
Acne dermatosis (rosacea, perioral dermatitis, seborrheic dermatitis etc.) are one of the most actual problem in dermatology. Praziquantel is an antiparasitic medication effective towards trematodes, cestodes.
D. M. Romanina, I. I. Berdey, V. V. Gladishev, G. P. Lisyanska   +3 more
doaj   +1 more source

Praziquantel and risk of visual disorders: Case series assessment.

PLoS Neglected Tropical Diseases, 2020
IntroductionPraziquantel has been in use by helminthiasis and schistosomiasis control programs for about 30 years. Although deemed to be safe with regard to its adverse drug reaction profile in reference to the product information of Biltricide, the ...
Merhawi Debesai, Mulugeta Russom
doaj   +1 more source