Results 31 to 40 of about 19,502 (213)

Dynamics of Schistosoma haematobium egg output and associated infection parameters following treatment with praziquantel in school-aged children [PDF]

, 2012
BACKGROUND: Praziquantel is the drug of choice in preventive chemotherapy targeting schistosomiasis. Increasing large-scale administration of praziquantel requires monitoring of drug efficacy to detect early signs of development of resistance.
Lohourignon Laurent K, Krauth, Stefanie J., Utzinger, Jürg, Coulibaly, Jean T., Jean T Coulibaly, Katarina Stete, Stefanie Knopp, Utzinger Jürg, N’Goran, Eliézer K., Stete, Katarina, Winfried V Kern, Lohourignon, Laurent K., Ivan Müller, Jürg Utzinger, Hattendorf Jan, Stete Katarina, Stefanie J Krauth, Coulibaly Jean T, Krauth Stefanie J, Müller Ivan, Laurent K Lohourignon, Müller, Ivan, N’Goran Eliézer K, Kern Winfried V, Hattendorf, Jan, N'Goran, Eliézer K., Knopp, Stefanie, Kern, Winfried V., Knopp Stefanie, Eliézer K N’Goran, Jan Hattendorf, N'goran EK, Knopp S, Hattendorf J, Kern WV, Utzinger J, Lohourignon LK, Krauth SJ, Müller I, Stete K, Coulibaly JT   +40 more
core   +1 more source

Resolution of Praziquantel

PLoS Neglected Tropical Diseases, 2011
Praziquantel remains the drug of choice for the worldwide treatment and control of schistosomiasis. The drug is synthesized and administered as a racemate. Use of the pure active enantiomer would be desirable since the inactive enantiomer is associated with side effects and is responsible for the extremely bitter taste of the pill.We have identified ...
Michael Woelfle, Jean-Paul Seerden, Jesse de Gooijer, Kees Pouwer, Piero Olliaro, Matthew H Todd   +5 more
openaire   +4 more sources

Toward measuring Schistosoma response to praziquantel treatment with appropriate descriptors of egg excretion [PDF]

, 2015
The control of schistosomiasis emphasizes preventive chemotherapy with praziquantel, which aims at decreasing infection intensity and thus morbidity in individuals, as well as transmission in communities.
Xiao-Nong Zhou (92570), Jennifer Keiser, Utzinger, Jürg, Michel Vaillant, King, Charles H., Jean T Coulibaly, Piero L. Olliaro (217564), José Carlos Sousa-Figueiredo (173724), Stefanie Knopp, Katarina Stete (213207), Olliaro, Piero L, Eliézer K. N’Goran (417750), Jean T. Coulibaly (108845), Jennifer Keiser (39606), Xiao-Nong Zhou, Garba, Amadou, Zhou, Xiao-Nong, Aly Landouré, Aly Landouré (264317), Olliaro, Piero L., Amadou Garba (125686), Landouré, Aly, Jürg Utzinger (39609), Stefanie Knopp (108848), Michel Vaillant (39101), Diawara, Aïssatou, Scherrer, Alexandra U, Amadou Garba, Coulibaly, Jean Tenena, Charles H. King (78462), Vaillant, Michel, Piero L Olliaro, Coulibaly, Jean T., Aïssatou Diawara, Scherrer, Alexandra U., King, Charles H, Sousa-Figueiredo, José Carlos, Katarina Stete, Charles H King, Alexandra U Scherrer, N’Goran, Eliézer K., Stete, Katarina, José Carlos Sousa-Figueiredo, Jürg Utzinger, Giovanna Raso, Giovanna Raso (51489), Alexandra U. Scherrer (214775), Raso, Giovanna, Coulibaly, Jean T, Aïssatou Diawara (5654983), Eliézer K N'Goran, Keiser, Jennifer, N'Goran, Eliézer K., Knopp, Stefanie, N'Goran, Eliézer K, Knopp S, Garba A, Raso G, King CH, Landouré A, Scherrer AU, Sousa-Figueiredo JC, Coulibaly JT, Stete K, Keiser J, Utzinger J, Olliaro PL, N'Goran EK, Diawara A, Zhou XN, Vaillant M   +70 more
core   +2 more sources

New approaches to measuring anthelminthic drug efficacy : parasitological responses of childhood schistosome infections to treatment with praziquantel [PDF]

, 2015
By 2020, the global health community aims to control and eliminate human helminthiases, including schistosomiasis in selected African countries, principally by preventive chemotherapy (PCT) through mass drug administration (MDA) of anthelminthics ...
Scherrer, A U, Raso, G, Utzinger, Jürg, Alexandra U. Scherrer, King, Charles H., Coulibaly, Jean T., Walker, Martin, Basanez, MG, Jean T. Coulibaly, Basáñez, M-G, King, CH, Martin Walker, Walker, M, Scherrer, Alexandra U., Sousa-Figueiredo, José Carlos, Katarina Stete, Mabud, Tarub S., Mabud, T, Stete, Katarina, Basáñez, Maria-Gloria, Coulibaly, J T, José Carlos Sousa-Figueiredo, Jürg Utzinger, Maria-Gloria Basáñez, Utzinger, J, Giovanna Raso, Scherrer, AU, Raso, Giovanna, Olliaro, Piero L., Stothard, JR, Stothard, J R, Sousa-Figueiredo, J C, Olliaro, PL, Coulibaly, JT, Sousa-Figueiredo, JC, Stothard, J. Russell, Charles H. King, King, C H, J. Russell Stothard, Tarub S. Mabud, Piero L. Olliaro, Olliaro, P L, Stete, K, Mabud TS, Stothard JR, Walker M, Basáñez MG, Raso G, King CH, Scherrer AU, Sousa-Figueiredo JC, Coulibaly JT, Stete K, Utzinger J, Olliaro PL   +54 more
core   +1 more source

Study of influence of the surface-active substances concentration on releasing of praziquantel from the rectal suppository

Фармацевтичний журнал, 2018
Acne dermatosis (rosacea, perioral dermatitis, seborrheic dermatitis etc.) are one of the most actual problem in dermatology. Praziquantel is an antiparasitic medication effective towards trematodes, cestodes.
D. M. Romanina, I. I. Berdey, V. V. Gladishev, G. P. Lisyanska   +3 more
doaj   +1 more source

Efficacy and safety of praziquantel, tribendimidine and mebendazole in patients with co-infection of Clonorchis sinensis and other helminths. [PDF]

PLoS Neglected Tropical Diseases, 2014
BackgroundBoth tribendimidine and mebendazole are broad-spectrum drugs for anti-intestinal nematodes. We aim to assess the efficacy and safety of tribendimidine and mebendazole in patients with co-infection of Clonorchis sinensis and other helminths ...
Li-Li Xu, Bin Jiang, Ji-Hui Duan, Shi-Feng Zhuang, Yong-Chun Liu, Shi-Qiao Zhu, Li-Ping Zhang, Hao-Bing Zhang, Shu-Hua Xiao, Xiao-Nong Zhou   +9 more
doaj   +1 more source

Does the presence of praziquantel-related adverse events affect the health community's perception toward the mass chemopreventive program in the highest prevalence area of Schistosomiasis in Indonesia? Study in Dodolo village, Napu Valley, Central Sulawesi

Gaceta Sanitaria, 2021
Objective: This study was to determine the relationship between a praziquantel-related adverse event with the health community perception to chemopreventive of Schistosomiasis in Dodolo village, Napu Valley, Central Sulawesi.
Ayu Sekarani Damana Putri, T. Vera Diana, Rahma Daris, Fitri Afriana, Serli Hatul Hidayat   +4 more
doaj   +1 more source

Praziquantel: its use in control of schistosomiasis in sub-Saharan Africa and current research needs [PDF]

, 2009
Treatment with praziquantel (PZQ) has become virtually the sole basis of schistosomiasis control in sub-Saharan Africa and elsewhere, and the drug is reviewed here in the context of the increasing rate that it is being used for this purpose. Attention is
Doenhoff, M.J., Southgate, V., Botros, S., Pica-Mattocia, L., Hagan, P., Coles, G., Tchuem, T.C.H.U., Mbaye, A., Engels, D., Cioli, D.   +9 more
core   +1 more source

Efficacy of praziquantel and artemisinin derivatives for the treatment and prevention of human schistosomiasis: a systematic review and meta-analysis

Parasites & Vectors, 2011
Background Praziquantel has been used as first-line drug for chemotherapy of schistosomiasis since 1984. Besides praziquantel, artemether and artesunate have also been used for the control of this infectious disease since late 1990s.
Zhao Qin-Ping, Guo Yi, Dong Hui-Fen, Liu Rong, Jiang Ming-Sen   +4 more
doaj   +1 more source

Integrated analysis of innate, Th1, Th2, Th17, and regulatory cytokines identifies changes in immune polarisation following treatment of human schistosomiasis. [PDF]

, 2012
BACKGROUND:  Schistosomiasis elicits cross-regulatory immune responses, but it is unclear how antihelminthic treatment affects this balance. This study integrates data on 13 cytokines elicited by 3 schistosome to examine how praziquantel treatment alters
Rujeni, N, Nausch, N, Mitchell, KM, Mutapi, Francisca, Appleby, Laura J, Midzi, Nicholas, Rujeni, Nadine, Bourke, Claire D, Mduluza, Takafira, Nausch, Norman, Appleby, LJ, Mduluza, T, Midzi, N, Mutapi, F, Bourke, CD, Mitchell, Kate M   +15 more
core   +1 more source