Results 61 to 70 of about 29,034 (242)
Tratamento da neurocisticercose com praziquantel [PDF]
Arquivos de Neuro-Psiquiatria, 1990 27 pacientes com neurocisticercose foram tratados com praziquantel, utilizado em doses progressivamente crescentes até alcançar 50 mg/kg/dia, por período de 21 dias, associado a dexametasona. Os doentes foram avaliados clínica e laboratorialmente durante o tratamento e, aqueles que completaram um ano de evolução, repetiram os testes imunofluorescência ...
Paulo Andrade de Mello +5 more
openaire +5 more sources
Clinical Case Reports, Volume 13, Issue 8, August 2025.ABSTRACT We report a case of imported Clonorchis sinensis infection under the modality of “visiting friends and relatives.” Clonorchis was not diagnosed initially, and a second stool sample was necessary. It is important that health personnel collect detailed information from the patient and be trained in parasitological diagnosis of imported ...
Paola Cociancic +2 more
wiley +1 more source
MCR Synthesis of Praziquantel Derivatives [PDF]
Chemical Biology & Drug Design, 2012 Schistosomiasis, a high volume neglected tropical disease affecting more than 200 million people worldwide, can only be effectively treated by the tetrahydroisoquinoline drug praziquantel (PZQ). Herein, we describe an efficient approach to access PZQ derivatives by the Ugi 4‐component reaction followed by the Pictet–Spengler reaction in a two‐step, one‐
Eberhardt Herdtweck +4 more
openaire +3 more sources
Pharmaceutics, 2019 Calcium carbonate is an abundant mineral with several advantages to be a successful carrier to improve oral bioavailability of poorly water-soluble drugs, such as praziquantel.
Ana Borrego-Sánchez +6 more
doaj +1 more source
Metabolic profiling of praziquantel enantiomers [PDF]
Biochemical Pharmacology, 2014 Praziquantel (PZQ), prescribed as a racemic mixture, is the most readily available drug to treat schistosomiasis. In the present study, ultra-performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight mass spectrometry (UPLC-ESI-QTOFMS) based metabolomics was employed to decipher the metabolic pathways and ...
Jeffrey R. Idle +8 more
openaire +3 more sources
Opportunities and challenges for modelling epidemiological and evolutionary dynamics in a multihost, multiparasite system: Zoonotic hybrid schistosomiasis in West Africa [PDF]
, 2017 Multihost multiparasite systems are evolutionarily and ecologically dynamic, which presents substantial trans‐disciplinary challenges for elucidating their epidemiology and designing appropriate control.
Borlase, A, Rudge, J W, Webster, J P
core +3 more sources
Efficacy of imidacloprid 10%/moxidectin 1% spot-on formulation (Advocate®) in the prevention and treatment of feline aelurostrongylosis [PDF]
, 2020 Background: In three randomized, controlled laboratory efficacy studies, the efficacy in the prevention of patent infections of a topical combination of imidacloprid 10%/moxidectin 1% (Advocate® spot-on formulation for cats, Bayer Animal Health GmbH ...
Blazejak, Katrin +9 more
core +1 more source
Veterinary Medicine and Science, Volume 11, Issue 4, July 2025.Letrozole increased the total antioxidant capacity and reduced malondialdehyde concentrations in both serum and seminal plasma. Letrozole increased parathormone and alkaline phosphatase levels in the serum. Letrozole decreased serum levels of IGF‐1, calcium, and 1, 25‐dihydroxy vitamin D.
Zahra Dadvand +7 more
wiley +1 more source
Menstrual disorders in rural Gambia.
, 2003 As part of a community-based reproductive morbidity survey in rural Gambia, the prevalence and association of menstrual disorders with sociodemographic characteristics and other reproductive morbidities, and with knowledge, attitudes, and beliefs ...
Coleman, Rosalind +5 more
core +1 more source
Advances in Mechanochemical Methods for One‐Pot Multistep Organic Synthesis
Chemistry – A European Journal, Volume 31, Issue 34, June 17, 2025.This review highlights recent advances in mechanochemical methods for multistep organic synthesis, focusing on sequential one‐pot approaches performed by grinding or ball milling. The presented transformations are discussed in terms of efficiency, applicability, and sustainability, assessing both the challenges and potential of solvent‐free one‐pot ...
Nina Biedermann, Michael Schnürch
wiley +1 more source