Results 81 to 90 of about 37,525 (284)

“Rapid-Impact Interventions”: How a Policy of Integrated Control for Africa's Neglected Tropical Diseases Could Benefit the Poor [PDF]

, 2005
Controlling seven tropical infections in Africa would cost just 40 cents per person per year, and would permanently benefit hundreds of millions of ...
Alan Fenwick, Commission for Africa, David H Molyneux, Peter J Hotez, The Lancet, The Lancet, UNAIDS, UNAIDS, What Works Working Group, What Works Working Group, World Bank, World Health Organization, World Health Organization, World Health Organization and Government of Mexico, World Health Organization, The Stop TB Partnership   +14 more
core   +4 more sources

Tratamento da neurocisticercose com praziquantel [PDF]

Arquivos de Neuro-Psiquiatria, 1990
27 pacientes com neurocisticercose foram tratados com praziquantel, utilizado em doses progressivamente crescentes até alcançar 50 mg/kg/dia, por período de 21 dias, associado a dexametasona. Os doentes foram avaliados clínica e laboratorialmente durante o tratamento e, aqueles que completaram um ano de evolução, repetiram os testes imunofluorescência ...
Paulo Andrade de Mello, Lucy Gomes Vianna, Julia Maria Costa, H. A. O. Souza, H. A. O. Souza, Vanize Macêdo   +5 more
openaire   +5 more sources

Research Progress on Influencing Factors of Gastrointestinal Microbial Diversity in Equine

Veterinary Medicine and Science, Volume 11, Issue 3, May 2025.
The gastrointestinal microbiota of equines is essential for their nutritional digestion and health. Studies have shown that breed, age, intestinal site, nutritional management and diseases have significant effects on the gastrointestinal microbial diversity of equines. Maintaining a balanced gastrointestinal microbiota is critical to equine health, and
Wei Zhang, Rong Guo, Ablat Sulayman, Yujiang Sun, Shuqin Liu   +4 more
wiley   +1 more source

Phenotypic and genotypic monitoring of Schistosoma mansoni in Tanzanian schoolchildren five years into a preventative chemotherapy national control programme [PDF]

, 2017
We conducted combined in vitro PZQ efficacy testing with population genetic analyses of S. mansoni collected from children from two schools in 2010, five years after the introduction of a National Control Programme.
A Fenwick, A Koukounari, AE Lelo, AJ Norton, AW Cheever, CD Criscione, Charlotte M. Gower, CM Gower, CM Gower, DG Colley, Florian Gehre, J Goudet, J Liu, J Wang, J Zwang, Joanne P. Webster, JP Webster, JP Webster, JW Rudge, LL Cavalli-Sforza, LM Barbosa, M Aemero, ML Steinauer, Nicholas J. Lwambo, OR Jones, PH Lamberton, PH Lamberton, PJ Hotez, Poppy H. L. Lamberton, RM Anderson, S William, Sara R. Marques, T Crellen, T de Meeus, T Huyse, WHO, YS Liang, ZN Kamvar   +37 more
core   +3 more sources

MCR Synthesis of Praziquantel Derivatives [PDF]

Chemical Biology & Drug Design, 2012
Schistosomiasis, a high volume neglected tropical disease affecting more than 200 million people worldwide, can only be effectively treated by the tetrahydroisoquinoline drug praziquantel (PZQ). Herein, we describe an efficient approach to access PZQ derivatives by the Ugi 4‐component reaction followed by the Pictet–Spengler reaction in a two‐step, one‐
Eberhardt Herdtweck, Sanaa S. Botros, Haixia Liu, Alexander Dömling, Samia William   +4 more
openaire   +3 more sources

Characteristics of Intestinal Flora in Patients With Schistosoma japonicum Infection Undergoing Splenectomy

Parasite Immunology, Volume 47, Issue 5, May 2025.
ABSTRACT Schistosomiasis japonica is a parasitic disease that seriously endangers human health. Patients with advanced Schistosoma japonicum infection often suffer from cirrhosis and portal hypertension. Splenectomy has been widely used in the treatment of these patients. Previous studies have confirmed that S. japonicum infection is closely related to
Chen Zhou, Pengpeng Zhang, Yingzi Ming
wiley   +1 more source

Investigations on the interplays between Schistosoma mansoni, praziquantel and the gut microbiome

Parasites & Vectors, 2018
BackgroundSchistosomiasis is a neglected tropical disease burdening millions of people. One drug, praziquantel, is currently used for treatment and control.
P. H. Schneeberger, J. Coulibaly, G. Panic, C. Daubenberger, M. Gueuning, J. Frey, J. Keiser   +6 more
semanticscholar   +1 more source

Safety of concurrent treatment of dogs with fluralaner (Bravecto™) and milbemycin oxime - praziquantel

Parasites & Vectors, 2014
Background Fluralaner (Bravecto™; Merck/MSD Animal Health) is a novel systemic ectoparasiticide for dogs providing long-acting flea and tick control after a single oral dose.
Feli M Walther, Petr Fisara, Mark J Allan, Rainer KA Roepke, Martin C Nuernberger   +4 more
doaj   +1 more source

Disseminated Neurocysticercosis With Intraventricular and Cisternal Extension Without Hydrocephalus: A Case Report

Clinical Case Reports, Volume 13, Issue 4, April 2025.
ABSTRACT Neurocysticercosis, a leading cause of acquired epilepsy, can present as disseminated disease with widespread cystic lesions. A 33‐year‐old male with seizures and weakness showed radiologically confirmed neurocysticercosis. Treatment with steroids, antiparasitics, and antiseizure medication led to improvement. Early diagnosis and public health
Bibek Shrestha, Priyesh Shrestha, Bikram Prasad Gajurel, Grishma Kandel, Laxmi Shah   +4 more
wiley   +1 more source

Estimation of changes in the force of infection for intestinal and urogenital schistosomiasis in countries with Schistosomiasis Control Initiative-assisted programmes [PDF]

, 2015
The last decade has seen an expansion of national schistosomiasis control programmes in Africa based on large-scale preventative chemotherapy. In many areas this has resulted in considerable reductions in infection and morbidity levels in treated ...
A Garba, AD Barbour, AD Barbour, AJ Fulford, AJ Fulford, Alan Fenwick, Amadou Garba, AP Plaisier, AP Plaisier, ARC Harris, AW Cheever, B Bolker, B Payet, BL Webster, BL Webster, BL Webster, BR Kirkwood, CH King, CH King, D Engels, D Gurarie, DL Smith, E Michael, E Miguel, EK N'Goran, Elisa Bosqué-Oliva, Fiona M. Fleming, G Webbe, GA Macdonald, GE Box, GF Medley, H Laamrani, H Tanaka, Hairston NG, HC Turner, HC Turner, HP Duerr, I Nåsell, I Nåsell, J Utzinger, J Utzinger, James Mwansa, JH Ouma, Joanne P. Webster, JP Webster, JW Rudge, JW Rudge, L Van Etten, LA Tchuem-Tchuenté, LA Tchuem-Tchuenté, Lynsey Blair, M Booth, M Parker, M Tanner, M-G Basáñez, M-G Basáñez, Maria-Gloria Basáñez, ME Woolhouse, Michael D. French, ML Steinauer, Moussa Sacko, MS Chan, MS Chan, MS Chan, N Katz, Narcis B. Kabatereine, NB Kabatereine, NG Hairston, RM Anderson, RM Anderson, RM Anderson, RM Anderson, RM May, Seydou Toure, SJ de Vlas, SM Blower, Team" RDC, Thomas S. Churcher, Ursuline Nyandindi, WHO   +79 more
core   +3 more sources