Results 91 to 100 of about 6,492 (168)

The effects of brown rice as functional food on Lee Index, adipose tissues and PRDM16 levels in obesity model Rattus norvegicus

Healthcare in Low-resource Settings
Brown rice is a functional food known to improve the Lee Index, influencing PRDM16 levels in obesity conditions. Therefore, this study aims to determine the differences in Lee Index, Brown Adipose Tissue (BAT) weight, White Adipose Tissue (WAT) weight ...
Jeany Pricelia, Putri Dwi Arini, Hazrina Putri Alifiyah, Riri Syabania, Inggita Kusumastuty, Etik Sulistyowati, Laksmi Sasiarini, Achmad Rudijanto, Dian Handayani   +8 more
doaj   +1 more source

Vascular smooth muscle cell PRDM16 regulates circadian variation in blood pressure

The Journal of Clinical Investigation
Disruptions of blood pressure (BP) circadian variation are closely associated with an increased risk of cardiovascular disease. Thus, gaining insights into the molecular mechanisms of BP circadian variation is essential for comprehending BP regulation ...
Zhenguo Wang, Wenjuan Mu, Juan Zhong, Ruiyan Xu, Yaozhong Liu, Guizhen Zhao, Yanhong Guo, Jifeng Zhang, Ida Surakka, Y. Eugene Chen, Lin Chang   +10 more
doaj   +1 more source

PRDM16 controls smooth muscle cell fate in atherosclerosis

Summary Vascular smooth muscle cells (SMCs) normally exist in a contractile state but can undergo fate switching to produce various cell phenotypes in response to pathologic stimuli 1–3 .
Tan, J.M.E., Cheng, Lan, Calhoun, Ryan P, Weller, Angela H, Drareni, Karima, Fong, Skylar, Barbara, Eirlys, Lim, Hee-Woong, Xue, Chenyi, Winter, Hanna, Auguste, Gaëlle, Miller, Clint L, Reilly, Muredach P, Maegdefessel, Lars, Lutgens, Esther, Seale, Patrick   +15 more
openaire   +2 more sources

CPEB2-activated Prdm16 translation promotes brown adipocyte function and prevents obesity

Molecular Metabolism
Objective: Brown adipose tissue (BAT) plays an important role in mammalian thermogenesis through the expression of uncoupling protein 1 (UCP1). Our previous study identified cytoplasmic polyadenylation element binding protein 2 (CPEB2) as a key regulator
Wen-Hsin Lu, Hui-Feng Chen, Pei-Chih King, Chi Peng, Yi-Shuian Huang   +4 more
doaj   +1 more source

Perivascular adipose tissue dysfunction contributes to thoracic aortic aneurysm development

Cardiovascular Diabetology
Background Thoracic aortic aneurysm (TAA) is a life-threatening disease with high morbidity and mortality rates due to fatal complications such as aortic rupture.
Zhenguo Wang, Wenjuan Mu, Ruiyan Xu, Juan Zhong, Wenhao Xiong, Xiangjie Zhao, Xiubin Liang, Yanhong Guo, Jifeng Zhang, Zhi-Sheng Jiang, Bo Yang, Y. Eugene Chen, Lin Chang   +12 more
doaj   +1 more source

PRDM16 is necessary for sensory neuronal development in the Trigeminal Ganglion

Abstract Background Cranial neural crest cells (cNCC) generate craniofacial cartilage, bone, and peripheral neurons and glia, and birth defects arise when the cartilage/neuronal/glial progenitor fail to differentiate.
Fahmida Raha, Qiman Gao, Lomeli C. Shull, Kristin B. Artinger   +3 more
openaire   +3 more sources

PRDM16 Gene [PDF]

, 2020
openaire   +1 more source

PRDM16 wt Allele [PDF]

, 2020
openaire   +1 more source

Overexpression of PRDM16 in the presence and absence of the RUNX1/PRDM16 fusion gene in myeloid leukemias [PDF]

Genes, Chromosomes and Cancer, 2006
Sawcène Hazourli, Pierre Chagnon, Martin Sauvageau, Raouf Fetni, Lambert Busque, Josée Hébert   +5 more
openaire   +1 more source

Marine n‐3 Polyunsaturated Fatty Acids Mitigate Obesity Traits Through PRDM16‐Driven Gene–Nutrient Interaction and Spatiotemporal Scale Browning Process

Food Frontiers
Marine n‐3 polyunsaturated fatty acids (PUFAs) as functional lipids are pivotal in controlling obesity but the mechanism is poorly understood. Herein, we unravel the role of n‐3 PUFAs in mitigating obesity traits through gene–nutrient interactions and ...
Xiaohui Liu, Haoyu Li, Youyou Zheng, Xiaoqian Chen, Xuzhi Wan, Pan Zhuang, Wei Jia, Jianxin Yao, Haoyin Liu, Hongbo Shi, Xunan Lin, Yu Zhang, Jingjing Jiao   +12 more
doaj   +1 more source